Omaha, NEBRASKA8 Active Studies

Lung Cancer Clinical Trials in Omaha, NEBRASKA

Find 8 actively recruiting lung cancer clinical trials in Omaha, NEBRASKA. Connect with local research sites and explore new treatment options.

8
Active Trials
6
Sponsors
1,823
Enrolling

Recruiting Lung Cancer Studies in Omaha

RecruitingOmaha, NEBRASKANCT06074588

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

The purpose of this study is to evaluate sacituzumab tirumotecan versus chemotherapy (docetaxel or pemetrexed) for the treatment of previously-treated non-small cell lung cancer (NSCLC) with exon 19de...

556 participants
Merck Sharp & Dohme LLC
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RecruitingOmaha, NEBRASKANCT04165070

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) with or without chemotherapy in combination with vibostolimab (MK-7684), boserolimab (MK-5890), MK-4830, MK-04...

450 participants
Merck Sharp & Dohme LLC
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RecruitingOmaha, NEBRASKANCT04317534

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

A randomized trial of adjuvant Pembrolizumab following surgical resection versus observation following surgical resection in patients with stage I non-small cell lung cancer (NSCLC) with primary tumor...

244 participants
Greg Durm, MD
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RecruitingOmaha, NEBRASKANCT05798663

Atezolizumab Immunotherapy With or Without Tiragolumab for Patients With Unresectable Stage III NSCLC

This is a phase II trial of neoadjuvant and adjuvant atezolizumab with or without tiragolumab in conjunction with chemoradiotherapy for unresectable stage III NSCLC....

178 participants
Alliance Foundation Trials, LLC.
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RecruitingOmaha, NEBRASKANCT06173505

Study of Vudalimab or Pembrolizumab in Combination With Chemotherapy as First-line Treatment in Patients With Advanced NSCLC

The purpose of this study is to identify the recommended dose of vudalimab to be used in combination with chemotherapy (Part 1) and to evaluate the efficacy and safety of vudalimab plus standard of ca...

168 participants
Xencor, Inc.
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RecruitingOmaha, NEBRASKANCT04938817

Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)

This study is a rolling arm study of investigational agents as monotherapy or in combination with pembrolizumab in participants with anti-programmed cell death 1 (PD-1)/ programmed cell death ligand 1...

110 participants
Merck Sharp & Dohme LLC
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RecruitingOmaha, NEBRASKANCT05860296

Testing Experimental Anti-cancer Drug SLC-391 with an Approved Immunotherapy Drug, Pembrolizumab, for Advanced Lung Cancers

SLC-391 is a novel, potent and specific small molecule inhibitor of receptor tyrosine kinase AXL with desirable potency and pharmaceutical properties. The study is being done to evaluate the safety a...

92 participants
SignalChem Lifesciences Corporation
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RecruitingOmaha, NEBRASKANCT06275360

Repositioning Immunotherapy in VetArans With Lung Cancer

This study is a multicenter Phase II single arm trial to assess the safety and efficacy of chemotherapy and immunotherapy followed by radiotherapy in patients with unresectable Stage III NSCLC....

25 participants
VA Office of Research and Development
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About Lung Cancer Clinical Trials in Omaha

Lung cancer is the leading cause of cancer death worldwide, starting in the cells of the lungs. The two main types are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Treatments include surgery, chemotherapy, radiation, immunotherapy, and targeted drugs.

There are currently 8 lung cancer clinical trials recruiting participants in Omaha, NEBRASKA. These studies are seeking a combined 1,823 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Greg Durm, MD, Alliance Foundation Trials, LLC. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lung Cancer Clinical Trials in Omaha — FAQ

Are there lung cancer clinical trials in Omaha?

Yes, there are 8 lung cancer clinical trials currently recruiting in Omaha, NEBRASKA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Omaha?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Omaha research site will contact you about next steps.

Are clinical trials in Omaha free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Omaha studies also compensate for your time and travel.

What lung cancer treatments are being tested?

The 8 active trials in Omaha are testing new therapies including novel drugs, biologics, and treatment approaches for lung cancer.

Data updated March 2, 2026 from ClinicalTrials.gov