Orange, CA6 Active Studies

Lupus Clinical Trials in Orange, CA

Find 6 actively recruiting lupus clinical trials in Orange, CA. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
1,866
Enrolling

Recruiting Lupus Studies in Orange

RecruitingOrange, CANCT04961567

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with systemic lupus erythematosus (SLE). The study will focus on participants who have active...

540 participants
Biogen
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RecruitingOrange, CANCT06015737

A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

This study aims to evaluate the efficacy and safety of subcutaneous (SC) anifrolumab versus placebo in adult participants with cutaneous lupus erythematosus (CLE)....

460 participants
AstraZeneca
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RecruitingOrange, CANCT05126277

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

This trial will evaluate efficacy, safety, and tolerability of subcutaneous (s.c.) ianalumab given every 4 weeks (q4w) or every 12 weeks (q12w) compared to placebo, in combination with SoC, in adult p...

420 participants
Novartis Pharmaceuticals
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RecruitingOrange, CANCT05138133

Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis

The purpose of this study is to evaluate the efficacy and safety of IV antifrolumab in adult patients with Active Proliferative Lupus Nephritis...

360 participants
AstraZeneca
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RecruitingOrange, CANCT05201469

VIBRANT: VIB4920 for Active Lupus Nephritis

This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in parti...

74 participants
National Institute of Allergy and Infectious Diseases (NIAID)
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RecruitingOrange, CANCT06121297

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus...

12 participants
Cabaletta Bio
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About Lupus Clinical Trials in Orange

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, brain, and other organs. It is more common in women and often involves periods of flares and remission. Treatment includes antimalarials, immunosuppressants, and biologics.

There are currently 6 lupus clinical trials recruiting participants in Orange, CA. These studies are seeking a combined 1,866 participants. Research is being sponsored by Biogen, AstraZeneca, Novartis Pharmaceuticals and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lupus Clinical Trials in Orange — FAQ

Are there lupus clinical trials in Orange?

Yes, there are 6 lupus clinical trials currently recruiting in Orange, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orange?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.

Are clinical trials in Orange free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.

What lupus treatments are being tested?

The 6 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for lupus.

Data updated March 2, 2026 from ClinicalTrials.gov