Recruiting Major Depressive Disorder Studies in Orange
About Major Depressive Disorder Clinical Trials in Orange
Major depressive disorder (MDD) is a severe form of depression characterized by persistent sadness, loss of interest, and impaired daily functioning. Treatment-resistant depression (TRD) affects patients who do not respond to standard therapies. Novel treatments like ketamine, psilocybin, and neuromodulation are being studied.
There are currently 7 major depressive disorder clinical trials recruiting participants in Orange, CA. These studies are seeking a combined 2,748 participants. Research is being sponsored by Neurocrine Biosciences, Vanda Pharmaceuticals, Cybin IRL Limited and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.
Major Depressive Disorder Clinical Trials in Orange — FAQ
Are there major depressive disorder clinical trials in Orange?
Yes, there are 7 major depressive disorder clinical trials currently recruiting in Orange, CA. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Orange?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.
Are clinical trials in Orange free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.
What major depressive disorder treatments are being tested?
The 7 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for major depressive disorder.
Data updated October 18, 2026 from ClinicalTrials.gov