Orange, CONNECTICUT6 Active Studies

Brain Cancer Clinical Trials in Orange, CONNECTICUT

Find 6 actively recruiting brain cancer clinical trials in Orange, CONNECTICUT. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
2,468
Enrolling

Recruiting Brain Cancer Studies in Orange

RecruitingOrange, CONNECTICUTNCT03970447

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/III response adaptive randomization platform trial designed to evaluate multiple...

1,280 participants
Global Coalition for Adaptive Research
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RecruitingOrange, CONNECTICUTNCT05580562

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant diffuse glioma to assess whether treatment with ONC...

450 participants
Chimerix
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RecruitingOrange, CONNECTICUTNCT05566795

DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monotherapy versus standard of care (SoC) chemotherapy in ...

400 participants
Day One Biopharmaceuticals, Inc.
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RecruitingOrange, CONNECTICUTNCT03550391

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to s...

206 participants
Canadian Cancer Trials Group
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RecruitingOrange, CONNECTICUTNCT03862430

A Study of NanO2â„¢ Combined With Radiation and Temozolomide in Patients With Newly Diagnosed GBM

This clinical trial is testing the safety and efficacy of NanO2TM administered via intravenous infusion in combination with standard radiation and chemotherapy. NanO2TM is being developed to increase...

87 participants
NuvOx LLC
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RecruitingOrange, CONNECTICUTNCT06413706

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

The purpose of this study is to measure the benefit of adding abemaciclib to the chemotherapy, temozolomide, for newly diagnosed high-grade glioma following radiotherapy. Your participation could las...

45 participants
Eli Lilly and Company
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About Brain Cancer Clinical Trials in Orange

Brain cancer includes tumors that originate in the brain (primary) or spread from other areas (metastatic). Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Treatment typically combines surgery, radiation, and chemotherapy, with immunotherapy trials underway.

There are currently 6 brain cancer clinical trials recruiting participants in Orange, CONNECTICUT. These studies are seeking a combined 2,468 participants. Research is being sponsored by Global Coalition for Adaptive Research, Chimerix, Day One Biopharmaceuticals, Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Brain Cancer Clinical Trials in Orange — FAQ

Are there brain cancer clinical trials in Orange?

Yes, there are 6 brain cancer clinical trials currently recruiting in Orange, CONNECTICUT. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orange?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.

Are clinical trials in Orange free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.

What brain cancer treatments are being tested?

The 6 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for brain cancer.

Data updated March 2, 2026 from ClinicalTrials.gov