8 Ovarian Cancer Clinical Trials in Orlando, FL (2026)

Q: How do I join a clinical trial in Orlando?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you.

Recruiting Ovarian Cancer Studies in Orlando

NCT07318558Recruiting

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

Researchers are looking for new ways to treat ovarian cancer (OC). Current treatment for OC may start with surgery to remove as much of the cancer as possible. After surgery, people may receive chemot...

Orlando, FLPHASE3900 participantsMerck Sharp & Dohme LLC

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NCT06819007Recruiting

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

This clinical trial is designed to evaluate the efficacy and safety of T-DXd in combination with bevacizumab versus bevacizumab monotherapy as first-line maintenance therapy, in participants with huma...

Orlando, FLPHASE3582 participantsDaiichi Sankyo

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NCT06915025Recruiting

Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

This is a randomized, adaptive, open label, multicenter trial to evaluate the safety and efficacy of intraperitoneal (IP) IMNN-001 plus chemotherapy compared to chemotherapy alone....

Orlando, FLPHASE3500 participantsImunon

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NCT07059845Recruiting

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

Ovarian cancer is a lethal disease with an estimated 310,000 new cases and 200,000 deaths experienced worldwide in 2020. The purpose of this study is to assess the adverse events and change in disease...

Orlando, FLPHASE2400 participantsAbbVie

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NCT06072781Recruiting

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (ICT) in subjects with recurrent LGSOC who have progr...

Orlando, FLPHASE3270 participantsVerastem, Inc.

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NCT06787612Recruiting

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

This study is researching an experimental drug called ubamatamab, also referred to as "study drug". The study is focused on patients who have advanced ovarian cancer. The aim of the study is to see h...

Orlando, FLPHASE2220 participantsRegeneron Pharmaceuticals

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NCT05281471Recruiting

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active...

Orlando, FLPHASE3186 participantsGenelux Corporation

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NCT05512208Recruiting

A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib

The purpose of this research is to test the effectiveness and safety of the study drugs (VS-6766 and defactinib), and see what effects (good and bad) these drugs have on the patients with endometrioid...

Orlando, FLPHASE255 participantsUniversity of Oklahoma

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About Ovarian Cancer Clinical Trials in Orlando

Ovarian cancer originates in the ovaries or fallopian tubes and is often called a "silent killer" due to subtle early symptoms. It is the fifth leading cause of cancer death among women. Treatment typically involves surgery and chemotherapy, with newer targeted therapies showing promise.

There are currently 8 ovarian cancer clinical trials recruiting participants in Orlando, FL. These studies are seeking a combined 3,113 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Daiichi Sankyo, Imunon and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ovarian Cancer Clinical Trials in Orlando — FAQ

Are there ovarian cancer clinical trials in Orlando?

Yes, there are 8 ovarian cancer clinical trials currently recruiting in Orlando, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orlando?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you about next steps.

Are clinical trials in Orlando free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orlando studies also compensate for your time and travel.

What ovarian cancer treatments are being tested?

The 8 active trials in Orlando are testing new therapies including novel drugs, biologics, and treatment approaches for ovarian cancer.

Data updated July 17, 2026 from ClinicalTrials.gov