3 Melanoma Clinical Trials in Orlando, FL (2026)

Q: How do I join a clinical trial in Orlando?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you.

Recruiting Melanoma Studies in Orlando

NCT05727904Recruiting

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

This is a Phase 3, multicenter, open-label, randomized, parallel group, treatment study to assess the efficacy and safety of lifileucel in combination with pembrolizumab compared with pembrolizumab al...

Orlando, FLPHASE3670 participantsIovance Biotherapeutics, Inc.

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NCT05549297Recruiting

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator choice (including cli...

Orlando, FLPHASE3540 participantsImmunocore Ltd

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NCT05361174Recruiting

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced non-small-cell lung cancer (NSCLC)....

Orlando, FLPHASE153 participantsIovance Biotherapeutics, Inc.

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About Melanoma Clinical Trials in Orlando

Melanoma is the most serious type of skin cancer, developing from the pigment-producing cells known as melanocytes. While less common than other skin cancers, melanoma is more likely to spread. Immunotherapy and targeted therapy have revolutionized melanoma treatment.

There are currently 3 melanoma clinical trials recruiting participants in Orlando, FL. These studies are seeking a combined 1,263 participants. Research is being sponsored by Iovance Biotherapeutics, Inc., Immunocore Ltd. Clinical trial participation is free and participants receive study-related medical care at no cost.

Melanoma Clinical Trials in Orlando — FAQ

Are there melanoma clinical trials in Orlando?

Yes, there are 3 melanoma clinical trials currently recruiting in Orlando, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orlando?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you about next steps.

Are clinical trials in Orlando free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orlando studies also compensate for your time and travel.

What melanoma treatments are being tested?

The 3 active trials in Orlando are testing new therapies including novel drugs, biologics, and treatment approaches for melanoma.

Data updated July 17, 2026 from ClinicalTrials.gov