Palo Alto, CA9 Active Studies

Spinal Muscular Atrophy Clinical Trials in Palo Alto, CA

Find 9 actively recruiting spinal muscular atrophy clinical trials in Palo Alto, CA. Connect with local research sites and explore new treatment options.

9
Active Trials
8
Sponsors
1,261
Enrolling

Recruiting Spinal Muscular Atrophy Studies in Palo Alto

NCT06538038Recruiting

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

The goal of the study is to collect data on patients treated outside of a clinical trial (in routine clinical practice) with standard of care osimertinib with or without chemotherapy in Epidermal Grow...

Palo Alto, CA538 participantsPrECOG, LLC.
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NCT06681220Recruiting

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

Randomized phase 2, multicenter, biomarker directed clinical trial with a safety lead-in to assess the efficacy of Stenoparib plus Temozolomide (TMZ) in relapsed Small Cell Lung Cancer patients. Parti...

Palo Alto, CAPHASE1166 participantsVA Office of Research and Development
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NCT04402788Recruiting

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

This phase II/III trial compares the effect of adding radiation therapy to the usual maintenance therapy with atezolizumab versus atezolizumab alone in patients who have already received atezolizumab ...

Palo Alto, CAPHASE2138 participantsNational Cancer Institute (NCI)
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NCT06839469Recruiting

Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

The purpose of this research is (1) to identify disease specific walking-related digital biomarkers of disease severity, and (2) monitor longitudinal changes in natural environments, for extended peri...

Palo Alto, CA106 participantsColumbia University
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NCT05866419Recruiting

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

The primary objective of the clinical investigation is to demonstrate successful clinical use of the ThecaFlex DRx™ System in delivering nusinersen in subjects with spinal muscular atrophy (SMA). All...

Palo Alto, CANA90 participantsAlcyone Therapeutics, Inc
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NCT06116682Recruiting

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a ...

Palo Alto, CAPHASE288 participantsSWOG Cancer Research Network
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NCT04616560Recruiting

Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Newly Diagnosed, Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

This phase I/II trial studies the effects of trastuzumab deruxtecan (DS-8201a) in treating patients with osteosarcoma, Wilms tumor (WT) or desmoplastic small round cell tumor (DSRCT) that is newly dia...

Palo Alto, CAPHASE155 participantsNational Cancer Institute (NCI)
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NCT07047144Recruiting

A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

This double-blind, Phase 2, multiple-dose study will be conducted to evaluate the PK/PD, efficacy, safety, and tolerability of apitegromab in subjects \<2 years old with 5q autosomal recessive SMA who...

Palo Alto, CAPHASE252 participantsScholar Rock, Inc.
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NCT05861999Recruiting

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

This is an open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam administered in pediatric participants with SMA and 2 SMN2 copies who previously rec...

Palo Alto, CAPHASE428 participantsHoffmann-La Roche
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About Spinal Muscular Atrophy Clinical Trials in Palo Alto

Spinal muscular atrophy (SMA) is a genetic neuromuscular disorder that causes loss of motor neurons, leading to progressive muscle weakness and atrophy. It is the leading genetic cause of infant death. Revolutionary gene therapies and SMN-enhancing drugs have transformed treatment.

There are currently 9 spinal muscular atrophy clinical trials recruiting participants in Palo Alto, CA. These studies are seeking a combined 1,261 participants. Research is being sponsored by PrECOG, LLC., VA Office of Research and Development, National Cancer Institute (NCI) and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Spinal Muscular Atrophy Clinical Trials in Palo Alto — FAQ

Are there spinal muscular atrophy clinical trials in Palo Alto?

Yes, there are 9 spinal muscular atrophy clinical trials currently recruiting in Palo Alto, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Palo Alto?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Palo Alto research site will contact you about next steps.

Are clinical trials in Palo Alto free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Palo Alto studies also compensate for your time and travel.

What spinal muscular atrophy treatments are being tested?

The 9 active trials in Palo Alto are testing new therapies including novel drugs, biologics, and treatment approaches for spinal muscular atrophy.

Data updated August 27, 2026 from ClinicalTrials.gov