12 COPD Clinical Trials in Philadelphia, PA (2026)

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Recruiting COPD Studies in Philadelphia

NCT06933758Recruiting

Temple Health Chest Initiative (THCI 2.0)

Chronic obstructive pulmonary disease is highly prevalent globally, with considerable morbidity and mortality associated. In the US, it is the 4th leading cause of death, as well as contributing to si...

Philadelphia, PA1,000 participantsTemple University

View Study Details

NCT06600126Recruiting

Supporting Evidence-based Responses to Emotional Needs in Emphysema

The goal of this clinical trial is to understand how a Coping Skills Training program can reduce depression and anxiety in people with chronic obstructive pulmonary disease (COPD), particularly those ...

Philadelphia, PANA750 participantsUniversity of Pennsylvania

View Study Details

NCT07684820Recruiting

To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment

This is a Phase 2 study of the efficacy, safety, tolerability and pharmacokinetics of two doses of EXPD-101 in participants with COPD. Study participants will be randomized to receive either study dru...

Philadelphia, PAPHASE2600 participantsExpedition Therapeutics, Inc

View Study Details

NCT07118306Recruiting

COPD Exacerbation Follow Up

The goal of this study is to evaluate the impact of implementing an AI-enabled clinical workflow tool (Viz COPD) on respiratory specialist follow up and clinical outcomes after an acute exacerbation....

Philadelphia, PA485 participantsViz.ai, Inc.

View Study Details

NCT06572384Recruiting

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

Interstitial lung disease (ILD) is a lung condition resulting in inflammation and stiffening of the lung, often associated with connective tissue diseases (CTDs). ILD causes reduction in lung volume, ...

Philadelphia, PAPHASE3440 participantsGlaxoSmithKline

View Study Details

NCT06974981Recruiting

Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry

The COPD in LCS Registry will identify and characterize individuals who have functional or radiographic evidence of COPD and are receiving lung cancer screening. Clinical information will be obtained ...

Philadelphia, PA420 participantsSidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

View Study Details

NCT07227376Recruiting

Data Collection Using Eko Digital Devices in a Clinical Setting

The purpose of this research is to prospectively train and validate an artificial intelligence machine learning (ML) algorithm to detect the presence of adventitious lung sounds in adults. Clinicians ...

Philadelphia, PA250 participantsEko Devices, Inc.

View Study Details

NCT07051707Recruiting

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

The dNerva Lung Denervation System is one-time treatment intended to improve breathing in Chronic Obstructive Pulmonary Disease (COPD) patients on standard medical care. The purpose of this study is t...

Philadelphia, PANA200 participantsNuvaira, Inc.

View Study Details

NCT06035120Recruiting

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

This is a prospective, open-label, multi-center, single-arm study planned to enroll 200 subjects with heterogeneous emphysema and collateral ventilation (CV) in the target lobe. Subjects will undergo ...

Philadelphia, PANA200 participantsPulmonx Corporation

View Study Details

NCT04302272Recruiting

STRIVE Post-Market Registry Study

This is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe emphysema in a post-m...

Philadelphia, PA150 participantsOlympus Corporation of the Americas

View Study Details

NCT07151768Recruiting

Prospective Validation of the Novel PVD-B65 Risk Score in Patients With Chronic Lung Disease and Pulmonary Hypertension

Prospective observational study to determine if the PVD-B65 risk score for one-year mortality in patients with chronic lung disease and pulmonary hypertension (CLD-PH) can accurately risk stratify the...

Philadelphia, PA100 participantsTemple University

View Study Details

NCT07222410Recruiting

Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

The trial aims to evaluate whether the Airvo 3 device in OptiO2 mode can maintain patients' SpO2 levels within the target range better than manual oxygen titration in hospitalized COPD patients with h...

Philadelphia, PANA70 participantsFisher and Paykel Healthcare

View Study Details

About COPD Clinical Trials in Philadelphia

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that makes breathing difficult, primarily caused by smoking. It includes emphysema and chronic bronchitis. Treatment involves bronchodilators, inhaled steroids, pulmonary rehabilitation, and oxygen therapy.

There are currently 12 copd clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 4,665 participants. Research is being sponsored by Temple University, University of Pennsylvania, Expedition Therapeutics, Inc and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

COPD Clinical Trials in Philadelphia — FAQ

Are there copd clinical trials in Philadelphia?

Yes, there are 12 copd clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What copd treatments are being tested?

The 12 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for copd.

Data updated July 17, 2026 from ClinicalTrials.gov