Philadelphia, PENNSYLVANIA5 Active Studies

Melanoma Clinical Trials in Philadelphia, PENNSYLVANIA

Find 5 actively recruiting melanoma clinical trials in Philadelphia, PENNSYLVANIA. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
813
Enrolling

Recruiting Melanoma Studies in Philadelphia

RecruitingPhiladelphia, PENNSYLVANIANCT03947385

Study of IDE196 in Patients with Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

This is a Phase 1/2, multi-center, open-label basket study designed to evaluate the safety and anti-tumor activity of IDE196 in patients with solid tumors harboring GNAQ or GNA11 (GNAQ/11) mutations o...

341 participants
IDEAYA Biosciences
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RecruitingPhiladelphia, PENNSYLVANIANCT05655312

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

In this first-in human, phase I/IIa study, the safety and efficacy of \[212Pb\]VMT01, an alpha-particle emitting therapeutic agent targeted to melanocortin sub-type 1 receptor (MC1R) is being evaluate...

264 participants
Perspective Therapeutics
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RecruitingPhiladelphia, PENNSYLVANIANCT06624644

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

The goal of this clinical trial is to understand if a new drug called LNS8801 can safely treat patients with melanoma. The primary question to be answered is what is the average length of time during ...

135 participants
Linnaeus Therapeutics, Inc.
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RecruitingPhiladelphia, PENNSYLVANIANCT03646617

Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma

The main purpose of this study is to determine the safety of combining ipilimumab and nivolumab with hypofractionated radiotherapy to a single tumor in patients with metastatic melanoma. Another purpo...

54 participants
Abramson Cancer Center at Penn Medicine
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RecruitingPhiladelphia, PENNSYLVANIANCT06414590

Neoadjuvant Tebentafusp for Uveal Melanoma

This phase II trial tests how well tebentafusp works to shrink tumors prior to primary treatment with surgery or radiation in patients with uveal (eye) melanoma that has spread to nearby tissue or lym...

19 participants
Thomas Jefferson University
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About Melanoma Clinical Trials in Philadelphia

Melanoma is the most serious type of skin cancer, developing from the pigment-producing cells known as melanocytes. While less common than other skin cancers, melanoma is more likely to spread. Immunotherapy and targeted therapy have revolutionized melanoma treatment.

There are currently 5 melanoma clinical trials recruiting participants in Philadelphia, PENNSYLVANIA. These studies are seeking a combined 813 participants. Research is being sponsored by IDEAYA Biosciences, Perspective Therapeutics, Linnaeus Therapeutics, Inc. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Melanoma Clinical Trials in Philadelphia — FAQ

Are there melanoma clinical trials in Philadelphia?

Yes, there are 5 melanoma clinical trials currently recruiting in Philadelphia, PENNSYLVANIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What melanoma treatments are being tested?

The 5 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for melanoma.

Data updated March 2, 2026 from ClinicalTrials.gov