Phoenix, AZ7 Active Studies

Melanoma Clinical Trials in Phoenix, AZ

Find 7 actively recruiting melanoma clinical trials in Phoenix, AZ. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
1,930
Enrolling

Recruiting Melanoma Studies in Phoenix

RecruitingPhoenix, AZNCT05549297

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator choice (including cli...

540 participants
Immunocore Ltd
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RecruitingPhoenix, AZNCT06346067

A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)

Stage 1: To select the optimal dose of naporafenib + trametinib to be studied in Stage 2. Stage 2: To compare progression free survival (PFS) and overall survival (OS) for patients with NRAS-mutant (...

470 participants
Erasca, Inc.
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RecruitingPhoenix, AZNCT06585410

Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

This study will test a study drug called cemiplimab to see if it can help treat early-stage cutaneous squamous cell carcinoma (CSCC), a type of skin cancer. Cemiplimab works by helping the immune syst...

369 participants
Regeneron Pharmaceuticals
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RecruitingPhoenix, AZNCT03567889

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients

The trial aims to evaluate the efficacy of Daromun neoadjuvant treatment followed by surgery and adjuvant therapy to improve in a statistically significant manner the recurrence-free survival (RFS) of...

186 participants
Philogen S.p.A.
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RecruitingPhoenix, AZNCT05136196

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

This phase II trial studies the good and bad effects of the combination of drugs called cabozantinib and nivolumab in treating patients with melanoma or squamous cell head and neck cancer that may hav...

150 participants
National Cancer Institute (NCI)
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RecruitingPhoenix, AZNCT04462406

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

This phase II trial investigates how well biomarkers on PET/CT imaging drive early discontinuation of anti-PD-1 therapy in patients with stage IIIB-IV melanoma that cannot be removed by surgery (unres...

150 participants
ECOG-ACRIN Cancer Research Group
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RecruitingPhoenix, AZNCT04349436

A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients With Advanced Cutaneous Malignancies

This Phase 1B/2 study is a multicenter, open-label, study of RP1 to investigate the (a) objective response rate, in addition to (b) safety and tolerability of RP1 for the treatment of advanced cutaneo...

65 participants
Replimune Inc.
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About Melanoma Clinical Trials in Phoenix

Melanoma is the most serious type of skin cancer, developing from the pigment-producing cells known as melanocytes. While less common than other skin cancers, melanoma is more likely to spread. Immunotherapy and targeted therapy have revolutionized melanoma treatment.

There are currently 7 melanoma clinical trials recruiting participants in Phoenix, AZ. These studies are seeking a combined 1,930 participants. Research is being sponsored by Immunocore Ltd, Erasca, Inc., Regeneron Pharmaceuticals and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Melanoma Clinical Trials in Phoenix — FAQ

Are there melanoma clinical trials in Phoenix?

Yes, there are 7 melanoma clinical trials currently recruiting in Phoenix, AZ. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Phoenix?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Phoenix research site will contact you about next steps.

Are clinical trials in Phoenix free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Phoenix studies also compensate for your time and travel.

What melanoma treatments are being tested?

The 7 active trials in Phoenix are testing new therapies including novel drugs, biologics, and treatment approaches for melanoma.

Data updated March 2, 2026 from ClinicalTrials.gov