31 Essential Tremor Clinical Trials in Pittsburgh, PA (2026)

Q: How do I join a clinical trial in Pittsburgh?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Pittsburgh research site will contact you.

Recruiting Essential Tremor Studies in Pittsburgh

NCT06104969Recruiting

DFC 004 Biomarkers for Active Diabetic Foot Ulcers

This study is a platform study designed to efficiently test multiple biomarkers to identify diabetic foot ulcers (DFUs) with a higher potential for healing versus not healing that ultimately could be ...

Pittsburgh, PA5,000 participantsUniversity of Michigan

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NCT07412002Recruiting

Quality of End-of-Life Care for Children With Cancer

This study examines the role of access to care, patient/family interactions with the healthcare system, and stress in explaining variations in quality of end of life care. The data collected from this...

Pittsburgh, PA2,425 participantsChildren's Oncology Group

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NCT06980025Recruiting

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

This is a phase-III multi-center double-blind randomized clinical trial of 1,800 individuals with a history of prior preterm birth at less than 35 weeks gestation who are randomized to either 162 mg a...

Pittsburgh, PA1,800 participantsThe George Washington University Biostatistics Center

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NCT02890342Recruiting

Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia

Background: People s bodies need to break down food into the chemicals. These chemicals are used for energy and growth. Some people cannot process all chemicals very well. Too much of some chemicals ...

Pittsburgh, PA1,045 participantsNational Human Genome Research Institute (NHGRI)

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NCT02995538Recruiting

Neurogenetics Patient Registry

The objective of this project is to develop a Neurogenetics patient database and bio repository - which includes clinical information regarding history, physical examination, laboratory testing includ...

Pittsburgh, PA1,000 participantsUniversity of Pittsburgh

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NCT05813678Recruiting

A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)

This is a 10-year multi-center, global, observational study to further characterize the safety profile of pegvaliase, including hypersensitivity reactions, long-term safety and tolerability, and the e...

Pittsburgh, PA450 participantsBioMarin Pharmaceutical

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NCT06351631Recruiting

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

The primary purpose of the study is to transition participants into an extension study to collect long-term safety and efficacy data. The study will include participants who are safely tolerating bome...

Pittsburgh, PA400 participantsMerck Sharp & Dohme LLC

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NCT06628128Recruiting

A Long-Term Study of JNT-517 in Participants With Phenylketonuria

The goal of this Phase 3, open-label study is to evaluate the long-term safety of JNT-517 in pediatric and adult participants with Phenylketonuria (PKU) after completion of either Study JNT517-101 (NC...

Pittsburgh, PA240 participantsOtsuka Pharmaceutical Development & Commercialization, Inc.

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NCT07214311Recruiting

Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

The goal of this clinical trial is to evaluate whether the investigational drug PLG0206 can help reduce recurrence of infection in adults who have undergone total knee replacement and are receiving a ...

Pittsburgh, PA240 participantsPeptilogics

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NCT07141706Recruiting

A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

This is a multicenter, open-label, multiple-dose, FIH Phase 1a/1b study. Phase 1a adopts an accelerated titration design and a BOIN design to identify the MTD or MAD of DB-1317; Phase 1b includes up t...

Pittsburgh, PA233 participantsDualityBio Inc.

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NCT06305234Recruiting

A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

This is a 10-year multi-center, prospective, longitudinal, single arm study evaluating immunologic, inflammatory and laboratory parameters associated with long-term Palynziq treatment in subjects with...

Pittsburgh, PA200 participantsBioMarin Pharmaceutical

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NCT06833853Recruiting

A Study for CTC Expression and cfDNA/RNA Assessment in Metastatic Breast Cancer Patients

The purpose of this research is to learn if the CellSearch Circulating Tumor Cells (CTC) test can help doctors in making decisions about treatment and monitoring of breast cancer. The test consists of...

Pittsburgh, PA187 participantsMenarini Silicon Biosystems, INC

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NCT05877430Recruiting

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

Study CJB-101-01 will be conducted at multiple centers in the USA and Republic of Korea as an open-label safety and preliminary efficacy study of CJRB-101 in combination with pembrolizumab in subjects...

Pittsburgh, PA160 participantsCJ Bioscience, Inc.

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NCT07061574Recruiting

A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

This multi-center randomized controlled trial will assess the safety and efficacy of ATG followed by either adalimumab or verapamil in preserving insulin secretion 2 years from randomization in person...

Pittsburgh, PA120 participantsCity of Hope Medical Center

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NCT06455969Recruiting

Adaptions and Resiliency to Multi-Stressor OpeRations

Non-combat-related muscle, tendon and bone injuries are the most common injuries suffered by military personnel, particularly in new recruits. These injuries impact military readiness and are responsi...

Pittsburgh, PA120 participantsBradley Nindl

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NCT07216118Recruiting

Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs

The goal of this clinical trial is to pilot test different strategies to address health related social needs (HRSN) experienced by adolescent and young adult patients with type 2 diabetes and their fa...

Pittsburgh, PA104 participantsUniversity of Pittsburgh

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NCT07423078Recruiting

Window of Opportunity in Preserving Laryngeal Function Trial

This trial will study the safety and tolerability and disease survival rates in adult patients with recurrent/metastatic (R/M) HNSCC when treated with carboplatin or cisplatin, paclitaxel, and toripal...

Pittsburgh, PA87 participantsMatthew Spector

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NCT07142252Recruiting

Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

This Phase 2 study is a 2-arm, multi-center, double-masked (masking of the participant, care provider and investigator), placebo-controlled, 2:1 randomized trial design in new onset T1D participants (...

Pittsburgh, PA66 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT06481592Recruiting

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

The purpose of this study is to investigate the efficacy and safety of the lifileucel regimen in participants with previously treated endometrial cancer....

Pittsburgh, PA60 participantsIovance Biotherapeutics, Inc.

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NCT07140900Recruiting

Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

The main objective of the trial is to evaluate the safety and tolerability of xaluritamig in combination with darolutamide or abiraterone....

Pittsburgh, PA60 participantsAmgen

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NCT04786262Recruiting

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

This study will evaluate the safety, tolerability and efficacy of VX-880 infusion in participants with Type 1 diabetes (T1D) and impaired awareness of hypoglycemia (IAH) and severe hypoglycemia....

Pittsburgh, PA52 participantsVertex Pharmaceuticals Incorporated

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NCT07493512Recruiting

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

The primary objective of this trial is to determine the safety profile of xaluritamig at the proposed regimen in adult participants with metastatic castration-resistant prostate cancer (mCRPC)....

Pittsburgh, PA40 participantsAmgen

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NCT06654037Recruiting

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

This phase I trial tests the safety, side effects, and best dose of abemaciclib in combination with 5-fluorouracil and how well it works in treating patients with colorectal cancer that has spread fro...

Pittsburgh, PA39 participantsNational Cancer Institute (NCI)

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NCT01894802Recruiting

Cortical Recording and Stimulating Array Brain-Machine Interface

The purpose of this research study is to demonstrate the safety and efficacy of using two CRS Arrays (microelectrodes) for long-term recording of brain motor cortex activity and microstimulation of br...

Pittsburgh, PA30 participantsMichael Boninger

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NCT06587165Recruiting

Quantifying New Heart Muscle Cells

Regenerative therapies could provide new ways of treating heart failure. Unlike many organs in the human body, such as the skin and the GI tract, the ability to regenerate heart muscle decreases after...

Pittsburgh, PA30 participantsWeill Medical College of Cornell University

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NCT07050173Recruiting

Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation

The goal of this clinical trial is to test whether the gamma - glutamylcystiene (GGC) oral supplement can reach the brain and subsequently increase antioxidant glutathione (GSH) level in people with r...

Pittsburgh, PA30 participantsPravat Mandal

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NCT07270016Recruiting

Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes

The goal of this study is to pilot test features of a new smartphone app and to gather feedback related to wearing a continuous glucose monitor (CGM) and a Fitbit device, as well as to obtain input on...

Pittsburgh, PA30 participantsUniversity of Pittsburgh

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NCT07121010Recruiting

How Animal and Plant Protein Shakes Change the Body's Nutrient and Health Responses

The goal of this clinical trial is to learn how different protein types affect the body's metabolism and immune system in healthy adults. The main questions it aims to answer are: Does drinking smoot...

Pittsburgh, PA20 participantsUniversity of Pittsburgh

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NCT06052839Recruiting

Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC

The rationale for the new sequence of pulsed dose chemotherapy proposed in this trial is based on the hypotheses that current standard dosing of chemotherapy plus pembrolizumab ultimately suppresses t...

Pittsburgh, PA15 participantsDan Zandberg

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NCT07282847Recruiting

A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late Onset Pompe Disease (PROGRESS-GT LOPD)

This is a single-arm, open-label, dose-escalation study to evaluate the safety, tolerability and efficacy of a single intravenous infusion of AB-1009 in adult participants with late-onset Pompe diseas...

Pittsburgh, PA12 participantsAskBio Inc

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NCT06832410Recruiting

An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

This study will evaluate the efficacy, safety, and tolerability of VX-880 in participants with Type 1 Diabetes (TID) with a kidney transplant....

Pittsburgh, PA10 participantsVertex Pharmaceuticals Incorporated

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About Essential Tremor Clinical Trials in Pittsburgh

Essential tremor is one of the most common movement disorders, causing involuntary shaking, most often in the hands. It is different from Parkinson's disease, though the two can be confused. Treatment includes medications, focused ultrasound, and deep brain stimulation for severe cases.

There are currently 31 essential tremor clinical trials recruiting participants in Pittsburgh, PA. These studies are seeking a combined 14,305 participants. Research is being sponsored by University of Michigan, Children's Oncology Group, The George Washington University Biostatistics Center and 22 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Essential Tremor Clinical Trials in Pittsburgh — FAQ

Are there essential tremor clinical trials in Pittsburgh?

Yes, there are 31 essential tremor clinical trials currently recruiting in Pittsburgh, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Pittsburgh?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Pittsburgh research site will contact you about next steps.

Are clinical trials in Pittsburgh free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Pittsburgh studies also compensate for your time and travel.

What essential tremor treatments are being tested?

The 31 active trials in Pittsburgh are testing new therapies including novel drugs, biologics, and treatment approaches for essential tremor.

Data updated July 13, 2026 from ClinicalTrials.gov