50 Ankylosing Spondylitis Clinical Trials in Rochester, MI (2026)

Q: How do I join a clinical trial in Rochester?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you.

Recruiting Ankylosing Spondylitis Studies in Rochester

NCT06057181Recruiting

Helix Research Network

The Helix Research Network ("HRN") is a network of academic, public, and/or private healthcare organizations that are committed to advancing medical research and improving human health through large-s...

Rochester, MI2,000,000 participantsHelix, Inc

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NCT07069400Recruiting

An International Observational Study of Adults With Acute Infection

Prospective, longitudinal studies of people with acute infections are essential to understand risk factors, clinical manifestations, pathobiology, and management strategies. Observational studies can ...

Rochester, MI1,500 participantsUniversity of Minnesota

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NCT02530983Recruiting

Mayo Clinic Upper Digestive Disease Survey

The Mayo Clinic Conduit Report Card Questionnaires have been created in order to have a consistent evaluation tools for patients undergoing esophageal reconstruction or treatment or patients that are ...

Rochester, MI1,000 participantsMayo Clinic

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NCT04703244Recruiting

Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer

Breast cancer patients who undergo neoadjuvant systemic therapy and have residual breast cancer identified at the time of surgery exhibit a high (\>50%) risk of future life-threatening recurrences and...

Rochester, MI999 participantsMayo Clinic

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NCT04365855Recruiting

The Olmsted NAFLD Epidemiology Study (TONES)

Researchers are assessing the prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in the population and assembling a well-characterized cohort of adults wit...

Rochester, MI800 participantsMayo Clinic

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NCT05427370Recruiting

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH3C) trial is a prospective, unblinded, international multi-center randomized trial of 754 subjects enrolled in approximately 45 ...

Rochester, MI754 participantsSunnybrook Health Sciences Centre

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NCT07483203Recruiting

A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease

The purpose of this study is to characterize pulmonary hemodynamic profiles, with a focus on PVR subtypes, in patients with left-sided valvular heart disease undergoing aortic or mitral valve interven...

Rochester, MI600 participantsMayo Clinic

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NCT03478761Recruiting

24-Hydroxylase Deficiency and CYP24A1 Mutation Patient Registry

You are being asked to take part in this research registry because you or your family member is suspected to have a 24-hydroxylase deficiency....

Rochester, MI600 participantsMayo Clinic

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NCT04799535Recruiting

Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring

This study evaluates the effectiveness of a breast ultrasound method for the diagnosis of breast cancer. Diagnostic procedures, such as breast ultrasound, may help find and diagnose breast cancer, and...

Rochester, MI550 participantsMayo Clinic

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NCT06469918Recruiting

The Co-Op @ HeartWorks

This protocol is a research study involving human subjects diagnosed with Congenital Heart Defects/Disease (CHD). The Co-Op @ HeartWorks is a cooperative between the research platform at HeartWorks an...

Rochester, MI500 participantsHeartWorks, Inc.

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NCT06188689Recruiting

Evaluation of A Clinical Diagnostic Test for CRDS

Calcium Release Deficiency Syndrome (CRDS) is a novel inherited arrhythmia syndrome secondary to RyR2 loss-of-function that confers a risk of sudden cardiac death. Diagnosis of CRDS presently requires...

Rochester, MI400 participantsPopulation Health Research Institute

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NCT06952543Recruiting

Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease

The purpose of this study is to develop a new noninvasive tool for early diagnosis of Peripheral Arterial Disease (PAD) and use the proposed method for monitoring the disease progression and the respo...

Rochester, MI400 participantsMayo Clinic

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NCT04821154Recruiting

Persona Revision Knee System Outcomes

The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision total knee arthroplasty (TKA) treatment. Thi...

Rochester, MI380 participantsZimmer Biomet

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NCT06410144Recruiting

Chronic Kidney Disease-Education (CKD-EDU)

The investigators are conducting a study to see which program better helps older patients with kidney disease choose their treatment. Investigators are also investigating if either program can reduce ...

Rochester, MI326 participantsUniversity of Rochester

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NCT06349642Recruiting

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

This study is being done to collect tissue samples to test how accurately a tumor response platform, Elephas, can predict clinical response across multiple types of immunotherapies, chemoimmunotherapy...

Rochester, MI324 participantsMayo Clinic

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NCT06533228Recruiting

Helmsley 3.0: Abbreviated MRE

The purpose of our study is to compare an abbreviated magnetic resonance imaging (MRI) of the bowel or magnetic resonance enterography (MRE) protocol to a conventional, standard of care MRE in childre...

Rochester, MI300 participantsChildren's Hospital Medical Center, Cincinnati

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NCT04142697Recruiting

Human Visual and Vestibular Motion Perception Study

The purpose this study is to measure sensitivity to visual and vestibular or balance motion. It is hoped that the results may help researchers better understand how aging and disease affect motion per...

Rochester, MI300 participantsUniversity of Rochester

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NCT05890677Recruiting

The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema

The aim of this study is to test whether lymphatic surgery provides better QoL (assessed with the Lymph-ICF-UL, (Lymphedema Functioning Disability and health questionnaire for upper limb lymphedema)) ...

Rochester, MI280 participantsUniversity Hospital, Basel, Switzerland

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NCT07213791Recruiting

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

This is a study of LY4337713 in participants with certain types of cancer that is advanced or has spread. Participants must have cancer with high levels of a protein called fibroblast activation prote...

Rochester, MI241 participantsEli Lilly and Company

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NCT06691932Recruiting

At-the-Breast vs. Expressed Human Milk: Genesis of Infant Nutrition (BEGIN)

The purpose of this study is to define human milk (HM) as an ecosystem which investigators will then combine into temporal models of milk dynamics to accurately describe HM chronobiology. This study a...

Rochester, MI240 participantsUniversity of Rochester

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NCT06200103Recruiting

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

This phase II trial studies how to improve the usage of Lu 177 vipivotide tetraxetan (177Lu-prostate-specific membrane antigen \[PSMA\]-617) for treating patients with castration-resistant prostate ca...

Rochester, MI236 participantsMayo Clinic

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NCT07060638Recruiting

Integrated Therapies for Alcohol Use in Alcohol-associated Liver Disease (ITAALD) Trial

This is a multicenter, randomized, double-blinded, placebo-controlled trial focused on the treatment of severe alcohol-associated hepatitis (sAH) and alcohol use disorder (AUD). The primary purpose o...

Rochester, MI216 participantsSamer Gawrieh

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NCT07054515Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-3102) in late-infantile and juvenile forms of Niemann...

Rochester, MI147 participantsAzafaros A.G.

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NCT06788886Recruiting

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers). The relations...

Rochester, MI147 participantsMayo Clinic

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NCT07103018Recruiting

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

Study K36-MCRPC-001 is the first in human clinical trial testing KTX-2001 alone and with darolutamide in men with metastatic castration-resistant prostate cancer. The study aims to assess whether the ...

Rochester, MI144 participantsK36 Therapeutics, Inc.

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NCT06879041Recruiting

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

The main purpose of the study is to assess the safety and tolerability of AZD2284, AZD2287, and AZD2275....

Rochester, MI136 participantsAstraZeneca

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NCT07190196Recruiting

A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

This is a Phase 3, parallel group, 2-arm, randomized, double blind, placebo-controlled, 52-week treatment study to assess the efficacy and safety of rilzabrutinib as a treatment for adult patients wit...

Rochester, MI124 participantsSanofi

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NCT06859801Recruiting

A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

The objective of this study is to evaluate real-world outcomes (e.g., pain, patient reported outcomes, skeletal related events, healthcare utilization, etc.) in patients treated with both percutaneous...

Rochester, MI120 participantsSociety of Interventional Oncology

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NCT03181048Recruiting

Clinical Trial of Concomitant Hip Arthroscopy During PAO

The study will assess the outcomes of patients treated with concomitant hip arthroscopy at the time of periacetabular osteotomy (PAO) for patients with hip dysplasia compared with patients treated wit...

Rochester, MI106 participantsMayo Clinic

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NCT07225621Recruiting

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

The purpose of this research is to test an investigational device using ultrasound along with an investigational drug to see if it is useful in treating glioblastoma following standard of care therapy...

Rochester, MI103 participantsAlpheus Medical, Inc.

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NCT06377696Recruiting

Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

This phase III trial evaluates whether patient care can be done remotely for patients having cranial (skull) radiation or who have previously had cranial radiation. In addition, this trial compares st...

Rochester, MI100 participantsMayo Clinic

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NCT06588426Recruiting

Clinical Readiness Skin Punch Biopsy Sample Collections

This is a clinical readiness skin punch biopsy sample collection study. This will allow to reduce manufacturing time when patients are identified as eligible to receive product under separate interven...

Rochester, MI100 participantsHeartWorks, Inc.

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NCT07305818Recruiting

NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease

The purpose of this study is to evaluate how well MER511 is tolerated and what side effects may occur in adults who have Graves' disease. The study drug will be administered either intravenously (into...

Rochester, MI100 participantsMerida Biosciences

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NCT06936566Recruiting

MAGIC Ruxolitinib for aGVHD

This clinical trial will study ruxolitinib-based treatment of acute graft-versus-host-disease (GVHD) that developed following allogeneic hematopoietic cell transplant. Acute GVHD occurs when donor cel...

Rochester, MI98 participantsJohn Levine

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NCT07278570Recruiting

Magnetic Resonance Elastography to Monitor Response to Manual Therapy in Myofascial Pain

The purpose of this research is to develop and test new Magnetic Resonance Imaging (MRI) methods that look at how muscles and tissues under the skin (myofascial tissues) move and respond to pressure. ...

Rochester, MI78 participantsMayo Clinic

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NCT07161544Recruiting

A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)

The purpose of the 039-101 study is to evaluate the safety and tolerability of a single subretinal injection of AAVB-039 in participants with Stargardt disease secondary to a biallelic mutation of the...

Rochester, MI75 participantsAAVantgarde Bio Srl

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NCT07082725Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

Rochester, MI72 participantsAzafaros A.G.

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NCT07087860Recruiting

Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers

This phase II trial compares therapeutic plasma exchange followed by enfortumab vedotin and pembrolizumab to standard of care next-line therapy for the treatment of patients with bladder or upper urin...

Rochester, MI70 participantsMayo Clinic

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NCT06557057Recruiting

Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk

This study assesses the effect of hormone directed treatment for breast cancer on glucose metabolism....

Rochester, MI66 participantsMayo Clinic

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NCT07525141Recruiting

A Study of JNJ-1761981 in Participants With Solid Tumors

The purpose of Part 1 of this study is to determine a safe, tolerable, and feasible recommended total dose of intratumorally administered JNJ-1761981. The purpose of Part 2 of this study is to identif...

Rochester, MI66 participantsJohnson & Johnson Enterprise Innovation Inc.

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NCT04630613Recruiting

NOX4 and Related Biomarkers in ADPKD

To determine the value of NOX4, markers of mitochondria injury and function, and oxidative stress as real-time biomarkers to assess disease severity in patients with early autosomal dominant polycysti...

Rochester, MI60 participantsMayo Clinic

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NCT07456852Recruiting

Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy

This phase I/II trial compares the effect of drugs that causes widening of blood vessels as a result of smooth muscle relaxation (vasodilator therapy) with isosorbide mononitrate, diltiazem or placebo...

Rochester, MI60 participantsMayo Clinic

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NCT06670638Recruiting

Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy

To date, patients with Crohn's Disease (CD) and permanent ileostomies have been excluded from clinical trials for new treatments. To allow this patient population to be included in clinical trials, ou...

Rochester, MI50 participantsAlimentiv Inc.

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NCT05753306Recruiting

Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP Study

This phase II clinical trial tests how well robotic cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) in treating patients with gastric cancer that has spread to the tissue that line...

Rochester, MI40 participantsMayo Clinic

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NCT05734404Recruiting

Longitudinal Study for Central Nervous System Vasculitis

Primary central nervous system vasculitis (CNSV) is a potentially fatal, single-organ vasculitis that often involves a spectrum of neurologic complications, including strokes, cognitive and speech imp...

Rochester, MI40 participantsUniversity of Pennsylvania

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NCT07468136Recruiting

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

This phase I/II trial tests the safety, side effects best dose and effect of retifanlimab with or without difluoromethylornithine (DFMO) for the treatment of high grade gliomas that are growing, sprea...

Rochester, MI33 participantsMayo Clinic

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NCT06306963Recruiting

Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias

The researchers are trying to find out more about Gastric Antral Vascular Ectasia (GAVE). This is a condition that affects the blood vessels in the stomach, leading to their enlargement and possible b...

Rochester, MI30 participantsMayo Clinic

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NCT07089927Recruiting

Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial

This clinical trial tests the feasibility, usability and acceptability of a virtual art therapy assisted re-integration (AVATARS) intervention to improve biopsychosocial outcomes, such as anxiety, dep...

Rochester, MI30 participantsMayo Clinic

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NCT06322602Recruiting

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

This observational trial evaluates the use of Ommaya reservoir placed during a biopsy to collect biomarkers longitudinally in patients with brain tumor. A biomarker is a measurable indicator of the se...

Rochester, MI20 participantsMayo Clinic

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NCT06953245Recruiting

Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing Radiotherapy

This study evaluates patient-reported experiences of radiation dermatitis in patients with breast cancer undergoing radiotherapy....

Rochester, MI20 participantsMayo Clinic

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About Ankylosing Spondylitis Clinical Trials in Rochester

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 50 ankylosing spondylitis clinical trials recruiting participants in Rochester, MI. These studies are seeking a combined 2,013,181 participants. Research is being sponsored by Helix, Inc, University of Minnesota, Mayo Clinic and 21 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Rochester — FAQ

Are there ankylosing spondylitis clinical trials in Rochester?

Yes, there are 50 ankylosing spondylitis clinical trials currently recruiting in Rochester, MI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Rochester?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you about next steps.

Are clinical trials in Rochester free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Rochester studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 50 active trials in Rochester are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated July 13, 2026 from ClinicalTrials.gov