10 Epilepsy Clinical Trials in Rochester, MI (2026)

Q: How do I join a clinical trial in Rochester?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you.

Recruiting Epilepsy Studies in Rochester

NCT02824822Recruiting

Genetic Markers of Cardiovascular Disease in Epilepsy

Epilepsy is a common condition which affects over 3 million people in the US. Patients with uncontrolled epilepsy have a lifetime risk of sudden unexpected death (SUDEP) of 35%, which is greatest in t...

Rochester, MI600 participantsMayo Clinic

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NCT07110454Recruiting

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

The purpose of this research is to address the challenges of correctly monitoring, managing, and diagnosing epilepsy in participants whose seizures are not well captured by standard electroencephalogr...

Rochester, MI210 participantsEpiminder America, Inc.

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NCT06934356Recruiting

Subcortical Arousal in Perceptual Awareness

The study consists of prospective enrollment of healthy participants and patients with epilepsy, as well as analysis of an existing data set. Healthy participants will be studied with fMRI, eye metric...

Rochester, MI202 participantsYale University

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NCT07219407Recruiting

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

This is a clinical research study for an investigational drug called RAP-219 in patients with Refractory Focal Epilepsy. This study is being conducted to determine RAP-219 Long- term safety and open-l...

Rochester, MI30 participantsRapport Therapeutics Inc.

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NCT05673915Recruiting

Study of Transcranial Direct Current Stimulation to Treat Epilepsy

The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic sei...

Rochester, MI30 participantsMayo Clinic

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NCT06617845Recruiting

Optimizing Brain Stimulation Parameters

A primary purpose of this study is to better understand what stimulation parameters work best for patients. For example, for Deep Brain Stimulation (DBS) of the Anterior Nucleus of the Thalamus (ANT),...

Rochester, MI30 participantsMayo Clinic

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NCT07227857Recruiting

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

Study CL1-230815-001 (KANDLE) is a Phase Ib/II, First In Human, multicentre, open-label, multiple ascending dose study to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD...

Rochester, MI20 participantsInstitut de Recherches Internationales Servier

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NCT07012148Recruiting

Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and Wearables

The purpose of this study is to evaluate the safety and feasibility of using seizure forecasts based on subscalp EEG....

Rochester, MI12 participantsMayo Clinic

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NCT05608408Recruiting

PRIME: PReservIng Memory in Epilepsy

In this study, participants will receive unilateral Deep Brain Stimulation (DBS) for treatment of epilepsy, with network-based stimulation targets specifically defined using a stereo-electro-encephalo...

Rochester, MI8 participantsNitin Tandon

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NCT06700356Recruiting

Thalamus Seizure Detection With a Deep Brain Stimulator System

The purpose of this study is to determine the feasibility of chronic ambulatory thalamus seizure detection. The sensitivity, specificity, and false alarm rate of thalamus seizure detection will be cal...

Rochester, MI5 participantsMayo Clinic

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About Epilepsy Clinical Trials in Rochester

Epilepsy is a neurological disorder characterized by recurrent, unprovoked seizures caused by abnormal electrical activity in the brain. It affects about 50 million people worldwide. Treatment includes antiseizure medications, surgery, and neurostimulation devices.

There are currently 10 epilepsy clinical trials recruiting participants in Rochester, MI. These studies are seeking a combined 1,147 participants. Research is being sponsored by Mayo Clinic, Epiminder America, Inc., Yale University and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Epilepsy Clinical Trials in Rochester — FAQ

Are there epilepsy clinical trials in Rochester?

Yes, there are 10 epilepsy clinical trials currently recruiting in Rochester, MI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Rochester?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you about next steps.

Are clinical trials in Rochester free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Rochester studies also compensate for your time and travel.

What epilepsy treatments are being tested?

The 10 active trials in Rochester are testing new therapies including novel drugs, biologics, and treatment approaches for epilepsy.

Data updated July 13, 2026 from ClinicalTrials.gov