39 Pulmonary Embolism Clinical Trials in Rochester, MI (2026)

Q: How do I join a clinical trial in Rochester?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you.

Recruiting Pulmonary Embolism Studies in Rochester

NCT04774159Recruiting

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

The Low dose ColchicinE in pAtients with peripheral Artery DiseasE to address residual vascular Risk (LEADER-PAD) trial will evaluate if anti-inflammatory therapy with colchicine will reduce vascular ...

Rochester, MI6,150 participantsPopulation Health Research Institute

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NCT05935605Recruiting

Pulmonary Hypertension in Left Heart Disease

The goal is to compare patients with and without varying severity of pulmonary vascular disease based upon hemodynamic signatures, echocardiographic measures, and lung ultrasound, in tandem with expir...

Rochester, MI3,000 participantsMayo Clinic

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NCT06676904Recruiting

Neonatal Platelet Transfusion Threshold Trial

The objective of the NeoPlaTT trial is to test whether, among extremely preterm infants born at 23 0/7 to 26 6/7 weeks' gestation, a lower platelet transfusion threshold, compared to a higher threshol...

Rochester, MI2,433 participantsNICHD Neonatal Research Network

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NCT00588562Recruiting

Rare Kidney Stone Consortium Patient Registry

The purpose of this study is to collect medical information from a large number of patients in many areas of the world with primary hyperoxaluria (PH), Dent disease, Cystinuria and APRT deficiency. Th...

Rochester, MI730 participantsMayo Clinic

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NCT07472491Recruiting

A Phase 2/3 Study on the Efficacy and Safety of Mangaciclanol for Contrast-Enhanced MRI of CNS or Body in Adult Patients

This is an operationally combined Phase 2/3 study, which will be conducted and evaluated in 2 distinct parts: * Phase 2: Prospective, adaptive, multicenter, non-randomized, single-blind, dose-finding...

Rochester, MI640 participantsGE Healthcare

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NCT07146516Recruiting

Retinal Detachment Prevention (Laser Prophylaxis) in Stickler Syndrome (SS)

The goal of this clinical trial is to prospectively document to what extent the OSC/SS prophylactic laser retinopexy procedure works to prevent retinal detachment in SS in children and adults. Resear...

Rochester, MI500 participantsHelen Keller Eye Research Foundation

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NCT06952543Recruiting

Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease

The purpose of this study is to develop a new noninvasive tool for early diagnosis of Peripheral Arterial Disease (PAD) and use the proposed method for monitoring the disease progression and the respo...

Rochester, MI400 participantsMayo Clinic

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NCT02780297Recruiting

Prospective Research Rare Kidney Stones (ProRKS)

The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and aden...

Rochester, MI220 participantsMayo Clinic

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NCT06638463Recruiting

My Health Coach App RCT

The goal of this clinical trial is to learn if the My Health Coach app helps adults with fetal alcohol spectrum disorders (FASD). The main questions it aims to answer are: Does the My Health Coach ap...

Rochester, MI200 participantsUniversity of Rochester

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NCT02305654Recruiting

International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)

This is an international phase III trial, with a Bayesian design, incorporating two sequential randomisations. It efficiently examines a series of questions that routinely arise in the sequencing of t...

Rochester, MI200 participantsInstitute of Cancer Research, United Kingdom

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NCT06614322Recruiting

SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy.

The goal of this clinical trial is to determine whether quantitative sensory testing (QST) can be used to classify participants into pain sub-groups and predict who will respond best to certain pain t...

Rochester, MI190 participantsUniversity of Rochester

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NCT07006142Recruiting

Effect of Prolonged Fasting Time on Gastric Residual Volume in Patients Taking GLP1 Receptor Agonists

The aim of this study is to determine whether a modified fasting protocol can reduce the potential risk of aspiration for patients currently prescribed GLP1-RAs....

Rochester, MI150 participantsMayo Clinic

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NCT04592445Recruiting

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

The purpose of this clinical study is to evaluate the safety and early effectiveness of a catheter-based procedure that treats a nerve called the right greater splanchnic nerve. The study includes peo...

Rochester, MI150 participantsAxon Therapies, Inc.

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NCT05334368Recruiting

Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial

This is a 52-week, randomized, placebo-controlled, double-blind, parallel group, multicenter study of depemokimab in adults with uncontrolled HES receiving standard of care (SoC) therapy. The study w...

Rochester, MI123 participantsGlaxoSmithKline

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NCT06751082Recruiting

Real World Observational Study of Sotatercept for Pulmonary Hypertension

The purpose of this study seeks to describe the real world initial experience with sotatercept in the treatment of pulmonary hypertension....

Rochester, MI120 participantsMayo Clinic

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NCT05481879Recruiting

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

The primary purpose of the study is to evaluate the safety and tolerability of multiple intravenous (IV) doses of DYNE-101 administered to participants with Myotonic Dystrophy Type 1 (DM1). The study...

Rochester, MI116 participantsDyne Therapeutics

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NCT07630389Recruiting

Remote Assessments and Genetic Determinants of Congenital and Childhood Myotonic Dystrophy

Myotonic dystrophy type 1 (DM1) can affect people in many different ways, even in the same family. The symptoms that children experience can be different and more severe than adults. Prior studies in ...

Rochester, MI100 participantsUniversity of Rochester

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NCT06695247Recruiting

A Study of Mobility Outcomes in Post-Pulmonary Embolic Disease

The purpose of this study is to develop a unique structure and delivery of home-based exercise through multidisciplinary expertise of cardiovascular medicine specialists and cardiac physiologists usin...

Rochester, MI100 participantsMayo Clinic

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NCT06784492Recruiting

Incorporating Healthy Living Strategies to Aid in Recovery After Acute Pulmonary Embolism

The purpose of the ERAsE-PE study is to determine whether two different healthy living strategies (along with anticoagulation) might aid in recovery after a patient is hospitalized for pulmonary embol...

Rochester, MI100 participantsUniversity of Rochester

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NCT07137286Recruiting

A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

The purpose of this study is to identify whether individuals following a ketogenic diet who experience extreme LDL-C elevation, termed "hyper-responders", have identifiable genetic variations in genes...

Rochester, MI100 participantsMayo Clinic

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NCT05551793Recruiting

Regeneron AA Multicenter (Dupilumab)

This is a prospective, randomized, double blind, placebo-controlled clinical trial. The study will take place at 4 sites. This trial will enroll a total of 68 patients with moderate to severe AA (affe...

Rochester, MI76 participantsEmma Guttman

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NCT06721013Recruiting

A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia

The purpose of the phase 1 part of this study is to evaluate how well pirtobrutinib is tolerated and what side effects may occur. The phase 2 part of the study will further investigate efficacy and sa...

Rochester, MI68 participantsEli Lilly and Company

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NCT07005050Recruiting

Renal Pelvic Denervation Pilot Trial

The RPD Pilot trial will evaluate the safety and effectiveness of Verve Medical's RPDTM renal denervation system for hypertensive patients with uncontrolled blood pressure despite use of two medicatio...

Rochester, MI60 participantsVerve Medical, Inc

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NCT06797193Recruiting

Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension

This clinical trial tests the how well an ultrasound with subharmonic imaging and the subharmonic aided pressure estimation (SHAPE) technique works in identifying portal hypertension (PH). An ultrasou...

Rochester, MI60 participantsMayo Clinic

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NCT07016009Recruiting

Thrive Person-Centered Planning Program for Young Adults With Fetal Alcohol Spectrum Disorders

This study evaluates the Thrive person centered planning program for young adults with fetal alcohol spectrum disorders. Participants are randomized to either an immediate start or delayed start group...

Rochester, MI60 participantsUniversity of Rochester

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NCT05163288Recruiting

A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

A pivotal, randomized, double-blind, placebo controlled, multi-center therapeutic study for patients age 4 and older with a confirmed diagnosis of Niemann Pick disease type C (NPC). The objective of t...

Rochester, MI53 participantsIntraBio Inc

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NCT06836232Recruiting

An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis

This is a study to understand if taking VTX2735 is safe and effective in participants diagnosed with Recurrent Pericarditis (RP). Approximately 30 patients will take VTX2735. The study consists of a ...

Rochester, MI50 participantsZomagen Biosciences Ltd.

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NCT06482814Recruiting

Sleep Restriction and Parental History of Hypertension

The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individual...

Rochester, MI44 participantsMayo Clinic

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NCT05836259Recruiting

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

This is a first-in-human, non-randomized, open-label study designed to evaluate the safety, tolerability, and pharmacodynamics (PD) of TN-201 in adult patients with symptomatic hypertrophic cardiomyop...

Rochester, MI30 participantsTenaya Therapeutics

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NCT04555161Recruiting

Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

This prospective study is a multi-center early feasibility study assessing the safety and performance of the Aria CV Pulmonary Hypertension System in patients with pulmonary hypertension and right hea...

Rochester, MI30 participantsAria CV, Inc

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NCT06104618Recruiting

Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous Cell Carcinoma of the Penis

This phase II trial tests how well enfortumab vedotin works for treating patients with squamous cell carcinoma of the penis that has spread to other places in the body (metastatic) or cannot be remove...

Rochester, MI28 participantsMayo Clinic

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NCT04580420Recruiting

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

The aim of this study is to evaluate DCR-PHXC in participants with PH1 and severe renal impairment, with or without dialysis....

Rochester, MI28 participantsDicerna Pharmaceuticals, Inc., a Novo Nordisk company

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NCT06839235Recruiting

Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)

The goal of the redePHine study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ABO-101 in participants with primary hyperoxaluria type 1 (PH1). The trial will consi...

Rochester, MI23 participantsArbor Biotechnologies

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NCT06508463Recruiting

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

This phase I trial studies the best dose and side effects of recombinant vesicular stomatitis virus (VSV) carrying the human (h) sodium iodide symporter (NIS) and Interferon (IFN) beta (β) genes (VSV-...

Rochester, MI21 participantsMayo Clinic

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NCT05933161Recruiting

A Study of Glycemic Control in Left Ventricular Assist

The study is being conducted to understand if the hemoglobin A1c, a measurement of control of blood sugars over a 3-month time, is valid in patients with Left Ventricular Assist Devices (LVADs) in pla...

Rochester, MI20 participantsMayo Clinic

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NCT07174349Recruiting

Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

The purpose of this research is to see if the use of tamsulosin can decrease both the incidence and duration of urinary retention, as well as hospital length of stay following spine surgery....

Rochester, MI20 participantsMayo Clinic

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NCT06668493Recruiting

Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to Renal Pelvis

The primary purpose of this trial is to evaluate the safety \& tolerability of Nadofaragene Firadenovec in subjects with LG-UTUC. To help with this evaluation, a safety lead-in period will be conducte...

Rochester, MI20 participantsFerring Pharmaceuticals

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NCT06881992Recruiting

A Phase 3 Study of Ersodetug in Patients With Tumor-Associated Hyperinsulinism

The objectives of this study are to evaluate the glycemic efficacy, safety, and tolerability of ersodetug for treatment of hypoglycemia in patients with Tumor-Associated Hyperinsulinism (tHI)....

Rochester, MI16 participantsRezolute

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NCT07054944Recruiting

Tumor-Lymph Node Mapping

The purpose of this study is to assess the feasibility and safety of ICG-guided intraoperative lymphography for detecting sentinel lymph nodes (SLN) in pediatric patients with solid tumors who require...

Rochester, MI10 participantsUniversity of Rochester

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About Pulmonary Embolism Clinical Trials in Rochester

Pulmonary embolism (PE) is a blockage of an artery in the lungs, usually caused by blood clots that travel from the deep veins of the legs. It can be life-threatening and requires immediate medical attention. Treatment includes anticoagulants and in severe cases, thrombolytic therapy.

There are currently 39 pulmonary embolism clinical trials recruiting participants in Rochester, MI. These studies are seeking a combined 16,439 participants. Research is being sponsored by Population Health Research Institute, Mayo Clinic, NICHD Neonatal Research Network and 18 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Embolism Clinical Trials in Rochester — FAQ

Are there pulmonary embolism clinical trials in Rochester?

Yes, there are 39 pulmonary embolism clinical trials currently recruiting in Rochester, MI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Rochester?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you about next steps.

Are clinical trials in Rochester free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Rochester studies also compensate for your time and travel.

What pulmonary embolism treatments are being tested?

The 39 active trials in Rochester are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary embolism.

Data updated July 13, 2026 from ClinicalTrials.gov