Rochester, MN6 Active Studies

Amyloidosis Clinical Trials in Rochester, MN

Find 6 actively recruiting amyloidosis clinical trials in Rochester, MN. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
553
Enrolling

Recruiting Amyloidosis Studies in Rochester

RecruitingRochester, MNNCT06788535

Research With I-124 EVuzamitide to Elucidate Cardiac AmyLoidosis

The purpose of this Phase 3, open label, single dose imaging study is to evaluate the efficacy and safety of I-124 evuzamitide (radioactive dye) for diagnosing Cardiac Amyloidosis in participants with...

200 participants
Sharmila Dorbala
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RecruitingRochester, MNNCT05898646

Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial

This phase II trial compares shorter-duration versus longer-duration maintenance therapy with daratumumab for improving survival in patients who have received initial treatment with daratumumab for li...

96 participants
Mayo Clinic
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RecruitingRochester, MNNCT07081646

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

Open-label Phase 1b/2 study with primary objective of this study is to evaluate the safety, tolerability and efficacy of AZD0120 in participants with light chain (AL) amyloidosis....

91 participants
Alexion Pharmaceuticals, Inc.
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RecruitingRochester, MNNCT06158854

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion

Immunoglobulin light chain (AL) amyloidosis is the most common form of systemic amyloidosis. AL amyloidosis has many root causes and is characterized by the overproduction of AL that are secreted by c...

76 participants
AbbVie
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RecruitingRochester, MNNCT05451771

Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis

The purpose of this study is assess safety, safest dose, and effectiveness of venetoclax in combination with dexamethasone in participants with t(11;14) positive relapsed (comes back) or refractory (d...

53 participants
Rajshekhar Chakraborty, MD
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RecruitingRochester, MNNCT05145816

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

The goal of this study is to test the safety of drug, Belantamab Mafodotin, and see what effects (good and bad) it has on people who take it and amyloidosis, and to determine the most effective dose o...

37 participants
University of Texas Southwestern Medical Center
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About Amyloidosis Clinical Trials in Rochester

Amyloidosis is a group of diseases in which abnormal proteins (amyloids) build up in organs and tissues, impairing their function. Types include AL, AA, and ATTR amyloidosis. Treatment depends on the type and may include chemotherapy, organ transplant, or targeted therapies.

There are currently 6 amyloidosis clinical trials recruiting participants in Rochester, MN. These studies are seeking a combined 553 participants. Research is being sponsored by Sharmila Dorbala, Mayo Clinic, Alexion Pharmaceuticals, Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Amyloidosis Clinical Trials in Rochester — FAQ

Are there amyloidosis clinical trials in Rochester?

Yes, there are 6 amyloidosis clinical trials currently recruiting in Rochester, MN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Rochester?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you about next steps.

Are clinical trials in Rochester free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Rochester studies also compensate for your time and travel.

What amyloidosis treatments are being tested?

The 6 active trials in Rochester are testing new therapies including novel drugs, biologics, and treatment approaches for amyloidosis.

Data updated March 2, 2026 from ClinicalTrials.gov