14 Spinal Muscular Atrophy Clinical Trials in Rochester, MN (2026)

Q: How do I join a clinical trial in Rochester?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you.

Recruiting Spinal Muscular Atrophy Studies in Rochester

NCT07190248Recruiting

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

Researchers want to learn if the study medicines calderasib and subcutaneous (SC) pembrolizumab can be used to treat non-small cell lung cancer (NSCLC) when given together. Calderasib is a targeted th...

Rochester, MNPHASE3675 participantsMerck Sharp & Dohme LLC

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NCT05091424Recruiting

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

This study will assess the safety, tolerability, pharmaokinetics, and preliminary efficacy of mosunetuzumab (Lunsumio) monotherapy in participants with relapsed or refractory (R/R) chronic lymphocytic...

Rochester, MNPHASE1332 participantsHoffmann-La Roche

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NCT07154290Recruiting

A Study to Investigate Ubamatamab With and Without REGN7075 in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

This study will evaluate two study drugs called ubamatamab and REGN7075, to see if they can help treat advanced or metastatic Non-Small Cell Lung Cancer (NSCLC), and sarilumab, to evaluate to see if i...

Rochester, MNPHASE2300 participantsRegeneron Pharmaceuticals

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NCT06252948Recruiting

Gut Microbiome Studies in Patients With POEMS Syndrome and Other Plasma Cell Disorders

A Study to Evaluate Gut Microbiome with POEMS Syndrome and Other Plasma Cell Disorders...

Rochester, MN240 participantsMayo Clinic

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NCT06139627Recruiting

Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

This clinical trial tests how well a geriatric assessment (GA) with GA-directed treatment recommendations, compared to GA with usual care, works in identifying risk factors, reducing chemotherapy radi...

Rochester, MNNA180 participantsCity of Hope Medical Center

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NCT06122064Recruiting

A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer

This clinical trial compares the use of a shared decision-making communication tool during a clinical encounter to standard care for improving the quality of the shared decision-making process among p...

Rochester, MNNA100 participantsMayo Clinic

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NCT06630806Recruiting

A Study to Investigate the Safety and Efficacy of SAR446523 Injected Subcutaneously in Adult Participants With Relapsed/Refractory Myeloma

This is a first-in-human study of SAR446523 conducted in patients with RRMM. The study consists of two parts: Dose escalation (Part A): In this part, up to several dose levels (DLs) of SAR446523 wil...

Rochester, MNPHASE187 participantsSanofi

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NCT05876923Recruiting

The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients

This clinical trial studies the effect of short-term (acute) and long-term (chronic) exercise on immune characteristics and function (phenotype) of patients with indolent non-Hodgkin lymphoma (NHL) an...

Rochester, MNNA70 participantsMayo Clinic

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NCT04297605Recruiting

Study of Pembrolizumab and Single Agent Chemotherapy as First Line Treatment for Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer With Eastern Cooperative Oncology Group (ECOG) Performance Status of 2

The purpose of this study is to understand if treatment with one chemotherapy medication combined with immune therapy (pembrolizumab) is tolerable and effective for patients with lung cancer and perfo...

Rochester, MNPHASE160 participantsUniversity of Rochester

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NCT06472804Recruiting

Insomnia in Patients With Metastatic Lung Cancer

This study evaluates how common insomnia (difficulties with sleep) is in patients with lung cancer that has spread from where it first started (primary site) to other places in the body....

Rochester, MN60 participantsMayo Clinic

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NCT06918132Recruiting

Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer

This phase II trial tests how well a fixed dose combination (FDC) of cemiplimab and fianlimab before surgery (neoadjuvant) works in treating patients with stage IB-IIIB non-small cell lung cancer (NSC...

Rochester, MNPHASE260 participantsMayo Clinic

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NCT06693336Recruiting

An Adjuvant Study to Evaluate SMS001 (Paclitaxel) in Non-Small Cell Lung Cancer

This study evaluates the use of SMS001 in patients with lung cancer. SMS001 is a new form of drug Paclitaxel. Doctors want to decide an appropriate safe dose for SMS001 administration, and to see how ...

Rochester, MNPHASE242 participantsToLymph Inc.

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NCT06660407Recruiting

Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer

This phase II trial tests the safety and effectiveness of the combination of grid radiation therapy and standard of care (SOC) immunotherapy in treating patients with stage IV non-small lung cancer (N...

Rochester, MNPHASE220 participantsMayo Clinic

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NCT07428044Recruiting

A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung Cancer

The purpose of this study is to find out how many people with HER2-amplified or HER2-mutated non-small cell lung cancer (NSCLC) experience a decrease in tumor viability when they receive trastuzumab d...

Rochester, MNPHASE214 participantsMemorial Sloan Kettering Cancer Center

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About Spinal Muscular Atrophy Clinical Trials in Rochester

Spinal muscular atrophy (SMA) is a genetic neuromuscular disorder that causes loss of motor neurons, leading to progressive muscle weakness and atrophy. It is the leading genetic cause of infant death. Revolutionary gene therapies and SMN-enhancing drugs have transformed treatment.

There are currently 14 spinal muscular atrophy clinical trials recruiting participants in Rochester, MN. These studies are seeking a combined 2,240 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Hoffmann-La Roche, Regeneron Pharmaceuticals and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Spinal Muscular Atrophy Clinical Trials in Rochester — FAQ

Are there spinal muscular atrophy clinical trials in Rochester?

Yes, there are 14 spinal muscular atrophy clinical trials currently recruiting in Rochester, MN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Rochester?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you about next steps.

Are clinical trials in Rochester free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Rochester studies also compensate for your time and travel.

What spinal muscular atrophy treatments are being tested?

The 14 active trials in Rochester are testing new therapies including novel drugs, biologics, and treatment approaches for spinal muscular atrophy.

Data updated August 31, 2026 from ClinicalTrials.gov