11 Pancreatic Cancer Clinical Trials in Rochester, MN (2026)

Q: How do I join a clinical trial in Rochester?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you.

Recruiting Pancreatic Cancer Studies in Rochester

NCT06271291Recruiting

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

This study evaluates individuals without pancreatic cancer, but who have been determined to be at higher-than-average lifetime risk of developing pancreatic cancer to help detect pancreatic cancer or ...

Rochester, MN30,000 participantsMayo Clinic

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NCT06151223Recruiting

A Prospective Registry for Patients at High-Risk for Pancreatic Cancer

This study aims to facilitate discovery and validation of tests for early detection in subjects at high risk for pancreatic ductal adenocarcinoma (PDAC) and to facilitate the use of state-of-the-art m...

Rochester, MN5,000 participantsMayo Clinic

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NCT03460769Recruiting

Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)

The Coordinating and Data Management Center (CDMC) at MD Anderson Cancer will be responsible for the coordination and data management for the Evaluation of a mixed meal test for Diagnosis and characte...

Rochester, MN775 participantsM.D. Anderson Cancer Center

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NCT05254171Recruiting

Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

The study is a randomized, double-blind, placebo-controlled, multicenter study of standard treatment with nab-paclitaxel and gemcitabine with or without SBP-101 in subjects previously untreated for me...

Rochester, MNPHASE2600 participantsPanbela Therapeutics, Inc.

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NCT07217717Recruiting

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of \[¹⁸F\]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically co...

Rochester, MNPHASE3200 participantsSOFIE

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NCT06922591Recruiting

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

TNG462-C102 is a Phase 1/2, open-label, multicenter study designed to determine the safety, tolerability, PK, PD, and preliminary antineoplastic activity of oral TNG462 in combination with RMC-6236 or...

Rochester, MNPHASE1183 participantsTango Therapeutics, Inc.

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NCT07644559Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic Cancer...

Rochester, MNPHASE2180 participantsVerastem, Inc.

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NCT05518903Recruiting

Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal Adenocarcinoma

This phase II trial tests whether 68Ga-FAPI-46 positron emission tomography (PET)/computed tomography (CT) scan works to image cancer-associated fibroblasts (CAFs) in patients with pancreatic ductal a...

Rochester, MNPHASE2130 participantsMayo Clinic

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NCT07226856Recruiting

BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma

This phase II trial tests the safety, side effects and best dose of BMS-986340 in combination with nivolumab, gemcitabine, and nab-paclitaxel and how well it works in treating patients with pancreatic...

Rochester, MNPHASE243 participantsMayo Clinic

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NCT04858009Recruiting

Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis

This phase II trial studies the effects of hyperthermic intraperitoneal chemotherapy (HIPEC) in treating patients with pancreatic cancer that has spread to the internal abdominal area (peritoneal meta...

Rochester, MNPHASE240 participantsMayo Clinic

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NCT07450859Recruiting

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

This is a Phase 2 study for nuzefatide pevedotin (BT5528) in adults with a specific type of pancreatic cancer called metastatic pancreatic ductal adenocarcinoma (PDAC) that has spread and worsened aft...

Rochester, MNPHASE239 participantsBicycleTx Limited

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About Pancreatic Cancer Clinical Trials in Rochester

Pancreatic cancer begins in the tissues of the pancreas and is often diagnosed at an advanced stage. It is one of the most challenging cancers to treat. Clinical trials are actively investigating new approaches including immunotherapy and combination regimens.

There are currently 11 pancreatic cancer clinical trials recruiting participants in Rochester, MN. These studies are seeking a combined 37,190 participants. Research is being sponsored by Mayo Clinic, M.D. Anderson Cancer Center, Panbela Therapeutics, Inc. and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pancreatic Cancer Clinical Trials in Rochester — FAQ

Are there pancreatic cancer clinical trials in Rochester?

Yes, there are 11 pancreatic cancer clinical trials currently recruiting in Rochester, MN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Rochester?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you about next steps.

Are clinical trials in Rochester free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Rochester studies also compensate for your time and travel.

What pancreatic cancer treatments are being tested?

The 11 active trials in Rochester are testing new therapies including novel drugs, biologics, and treatment approaches for pancreatic cancer.

Data updated September 1, 2026 from ClinicalTrials.gov