Rochester, NY4 Active Studies

Head and Neck Cancer Clinical Trials in Rochester, NY

Find 4 actively recruiting head and neck cancer clinical trials in Rochester, NY. Connect with local research sites and explore new treatment options.

4
Active Trials
3
Sponsors
1,069
Enrolling

Recruiting Head and Neck Cancer Studies in Rochester

RecruitingRochester, NYNCT06790966

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

This is a global, multi-center, Phase 3 study that is randomized 2:1, controlled, and open label to evaluate PDS0101 (Versamune + HPVMix) in combination with pembrolizumab vs. pembrolizumab monotherap...

351 participants
PDS Biotechnology Corp.
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RecruitingRochester, NYNCT05541016

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

This phase II trial examines the use of blood-based biomarkers is to help inform decision making for treatment and radiation therapy for patients with human papillomavirus (HPV) positive oropharyngeal...

320 participants
Mayo Clinic
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RecruitingRochester, NYNCT04915183

Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

Background: Cisplatin is used to treat head and neck cancer. People who take this drug are at risk for hearing loss. Atorvastatin is a drug used to treat high cholesterol. It might reduce the risk of...

224 participants
National Institute on Deafness and Other Communication Disorders (NIDCD)
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RecruitingRochester, NYNCT05075980

Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study

This clinical trial studies how well intensity modulated proton therapy (IMPT) or intensity modulated X-ray (radiation) therapy (IMRT) works after surgery in treating patients with head and neck cance...

174 participants
Mayo Clinic
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About Head and Neck Cancer Clinical Trials in Rochester

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 4 head and neck cancer clinical trials recruiting participants in Rochester, NY. These studies are seeking a combined 1,069 participants. Research is being sponsored by PDS Biotechnology Corp., Mayo Clinic, National Institute on Deafness and Other Communication Disorders (NIDCD). Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Rochester — FAQ

Are there head and neck cancer clinical trials in Rochester?

Yes, there are 4 head and neck cancer clinical trials currently recruiting in Rochester, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Rochester?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you about next steps.

Are clinical trials in Rochester free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Rochester studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 4 active trials in Rochester are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated March 2, 2026 from ClinicalTrials.gov