11 Obesity Clinical Trials in San Diego, CA (2026)

Q: How do I join a clinical trial in San Diego?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you.

Recruiting Obesity Studies in San Diego

NCT07654361Recruiting

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

Study GSBR-1290-12 is a Phase 3 pivotal, multicenter, global, randomized, placebo-controlled, double-blind study to investigate the long-term efficacy, safety, and tolerability of 3 maintenance doses ...

San Diego, CAPHASE33,600 participantsGasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

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NCT07684235Recruiting

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

The primary objective of this trial is to evaluate the long-term efficacy, safety, and tolerability of maridebart cafraglutide in participants with obesity or overweight. Trial 20250197 is an extensio...

San Diego, CAPHASE33,200 participantsAmgen

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NCT07351045Recruiting

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA), at multi...

San Diego, CAPHASE32,000 participantsHoffmann-La Roche

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NCT07392190Recruiting

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo in participants with persistent obesity or overweight, with or without type 2 diabetes, and ...

San Diego, CAPHASE3900 participantsEli Lilly and Company

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NCT07571005Recruiting

AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

This study is being done to look at the efficacy and safety of NNC0487-0111 in participants with excess body weight and obstructive sleep apnoea not treated with positive airway pressure lose weight a...

San Diego, CAPHASE3300 participantsNovo Nordisk A/S

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NCT07575399Recruiting

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

Efficacy, safety and tolerability of switching from GLP-1RA to maridebart cafraglutide in adults with obesity or overweight....

San Diego, CAPHASE3300 participantsAmgen

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NCT06596902Recruiting

Promoting Physical Activity and Fitness Among Underserved Latino Families Living in U.S.-Mexico Border Regions

This study has the goal to increase physical activity and fitness among Latinos in San Diego, California and Mexicali, Baja California (U.S.-Mexico border) since these cities have similar diseases suc...

San Diego, CANA290 participantsSan Diego State University

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NCT07441252Recruiting

A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

The main objective of this trial will be to determine whether maridebart cafraglutide is superior to placebo on reduction in liver fat content and body weight in participants living with obesity or ov...

San Diego, CAPHASE2180 participantsAmgen

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NCT06323070Recruiting

Effects of Watermelon or Low-fat Cookie Consumption on Wellness

The objective of the proposed research is to determine the effects of fresh watermelon consumption on physiological indicators of wellness regarding sexual, skin and gut health in adults....

San Diego, CANA80 participantsSan Diego State University

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NCT06783751Recruiting

Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)

This is a two-site randomized clinical trial aiming to test whether a modified investigational bariatric surgical procedure can improve gastroesophageal reflux disease (GERD) after sleeve gastrectomy....

San Diego, CANA44 participantsUniversity of California, Irvine

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NCT05726942Recruiting

Efficacy of mHealth Applications in Weight Management in a Population Affected by Overweight or Obesity

The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes in patients with overweight and obesity. This study will involve a 6-month long c...

San Diego, CANA30 participantsSan Diego State University

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About Obesity Clinical Trials in San Diego

Obesity is a complex chronic disease involving an excessive amount of body fat that increases the risk of other diseases and health problems. It affects over 650 million adults worldwide. Treatment approaches include lifestyle modifications, medications (GLP-1 agonists), and bariatric surgery.

There are currently 11 obesity clinical trials recruiting participants in San Diego, CA. These studies are seeking a combined 10,924 participants. Research is being sponsored by Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics, Amgen, Hoffmann-La Roche and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Obesity Clinical Trials in San Diego — FAQ

Are there obesity clinical trials in San Diego?

Yes, there are 11 obesity clinical trials currently recruiting in San Diego, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Diego?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you about next steps.

Are clinical trials in San Diego free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Diego studies also compensate for your time and travel.

What obesity treatments are being tested?

The 11 active trials in San Diego are testing new therapies including novel drugs, biologics, and treatment approaches for obesity.

Data updated September 7, 2026 from ClinicalTrials.gov