11 Type 2 Diabetes Clinical Trials in San Diego, CA (2026)

Q: How do I join a clinical trial in San Diego?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you.

Recruiting Type 2 Diabetes Studies in San Diego

NCT07296484Recruiting

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

CAPTAIN-T2D will take place in two parts. Part 1 (Screening) will evaluate patients with type 2 diabetes and elevated cortisol risk factors for trial eligibility and the presence of elevated cortisol....

San Diego, CAPHASE21,500 participantsSparrow Pharmaceuticals

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NCT07662044Recruiting

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus

The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron alone or in combination with dapagliflozin compared with placebo in adults with type 2 diabetes mellitus...

San Diego, CAPHASE3800 participantsAstraZeneca

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NCT06628453Recruiting

CGM for Management of Type 2 Diabetes in Pregnancy

The goal of this clinical trial is to learn if continuous glucose monitoring works better than self-monitoring of blood glucose (fingersticks) to treat type 2 diabetes in pregnancy. It will also learn...

San Diego, CANA564 participantsUniversity of Alabama at Birmingham

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NCT07415954Recruiting

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

This study is being done to look at the effect and safety of different doses of NNC0662-0419 in people living with type 2 diabetes when compared to placebo or semaglutide. The purpose of this clinical...

San Diego, CAPHASE2270 participantsNovo Nordisk A/S

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NCT05138432Recruiting

More Fresh Fruit and Vegetable Prescription Program for Families With Type 2 Diabetes Mellitus

Rady Children's Hospital San Diego (RCHSD), UCSD Division of Child and Community Health and the Center for Community Health, and Northgate Gonzalez (NG) Markets will collaborate to create a Produce Pr...

San Diego, CANA200 participantsUniversity of California, San Diego

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NCT07285018Recruiting

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain

The purpose of this study is to test the safety and efficacy of study drug LY4065967 for the treatment of diabetic peripheral neuropathic pain (DPNP). This trial is part of the chronic pain master pro...

San Diego, CAPHASE2150 participantsEli Lilly and Company

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NCT07116174Recruiting

A Prospective Clinical Study to Evaluate the Effectiveness and Safety of Xcell Amnio MatrixTM (XAM) in the Management of Chronic Non-healing DFUs

The goal of this clinical trial is to evaluate the clinical outcomes of Diabetic Foot Ulcers (DFUs) treated with a weekly application of Xcell Amnio MatrixTM (XAM) as adjunct to standard of care (SOC)...

San Diego, CANA135 participantsNew Horizon Medical Solutions

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NCT07502508Recruiting

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy

This is a phase 2 randomized, double-blind, placebo-controlled trial assessing the efficacy and safety of icovamenib in participants with Type 2 Diabetes (T2D) not achieving glycemic targets despite O...

San Diego, CAPHASE260 participantsBiomea Fusion Inc.

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NCT05279729Recruiting

Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population

The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and the subsequent benefit of improving type II diabetes outcomes in a low socioe...

San Diego, CANA45 participantsSan Diego State University

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NCT07065721Recruiting

Continuous Glucose Monitoring for Self-Management of Type 2 Diabetes in Young Adults

Type 2 diabetes in increasing common in young adults. Utilizing a mixed-methods, community-based approach, this study offers continuous glucose monitors (CGMs) to young adults with type 2 diabetes for...

San Diego, CANA40 participantsSan Diego State University

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NCT05589155Recruiting

Efficacy of Using Mobile Health Applications for Health

The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and type II diabetes outcomes in type 2 diabetics. This study will involve a 6-mo...

San Diego, CANA30 participantsSan Diego State University

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About Type 2 Diabetes Clinical Trials in San Diego

Type 2 diabetes is a chronic metabolic condition affecting over 37 million Americans, characterized by insulin resistance and progressive loss of beta-cell function. While metformin remains the first-line treatment, the treatment landscape has expanded dramatically with GLP-1 receptor agonists (semaglutide, tirzepatide), SGLT2 inhibitors (empagliflozin, dapagliflozin), and dual GIP/GLP-1 agonists showing both glycemic and cardiovascular benefits. Clinical trials are now exploring triple-hormone agonists, oral GLP-1 formulations, islet cell regeneration therapies, and precision medicine approaches that tailor treatment to individual metabolic profiles. Patients with uncontrolled HbA1c on current medications, those with diabetic complications, or newly diagnosed patients may qualify for enrollment.

There are currently 11 type 2 diabetes clinical trials recruiting participants in San Diego, CA. These studies are seeking a combined 3,794 participants. Research is being sponsored by Sparrow Pharmaceuticals, AstraZeneca, University of Alabama at Birmingham and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Type 2 Diabetes Clinical Trials in San Diego — FAQ

Are there type 2 diabetes clinical trials in San Diego?

Yes, there are 11 type 2 diabetes clinical trials currently recruiting in San Diego, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Diego?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you about next steps.

Are clinical trials in San Diego free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Diego studies also compensate for your time and travel.

What type 2 diabetes treatments are being tested?

The 11 active trials in San Diego are testing new therapies including novel drugs, biologics, and treatment approaches for type 2 diabetes.

Data updated September 7, 2026 from ClinicalTrials.gov