San Diego, CALIFORNIA23 Active Studies

Myalgic Encephalomyelitis Clinical Trials in San Diego, CALIFORNIA

Find 23 actively recruiting myalgic encephalomyelitis clinical trials in San Diego, CALIFORNIA. Connect with local research sites and explore new treatment options.

23
Active Trials
19
Sponsors
4,047
Enrolling

Recruiting Myalgic Encephalomyelitis Studies in San Diego

RecruitingSan Diego, CALIFORNIANCT06976203

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC for cognitive impairment in Alzheimer's Disease...

586 participants
Bristol-Myers Squibb
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RecruitingSan Diego, CALIFORNIANCT06544616

A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease

The purpose of this study is to assess the effect of JNJ-64042056 on cognitive decline, as measured by Preclinical Alzheimer's disease Cognitive Composite 5 (PACC-5) compared with placebo....

498 participants
Janssen Pharmaceutica N.V., Belgium
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RecruitingSan Diego, CALIFORNIANCT06153420

Study of the Research Medicine CIN-103 in Adults with Irritable Bowel Syndrome with Predominant Diarrhea (IBS-D).

The goal of this clinical trial is to evaluate if the study drug, CIN-103, can help reduce the symptoms associated with irritable bowel syndrome with predominant diarrhea (IBS-D) in adult patients. Th...

450 participants
CinPhloro Pharma, LLC
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RecruitingSan Diego, CALIFORNIANCT06233799

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

The primary objective of this study is to evaluate the efficacy of extended release naltrexone plus bupropion XL (XR-NTX/BUP-XL) compared to matched injectable and oral placebo (iPLB/oPLB) in reducing...

360 participants
National Institute on Drug Abuse (NIDA)
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RecruitingSan Diego, CALIFORNIANCT07011745

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC in adult participants with agitation related to Alzheimer's Disease....

352 participants
Bristol-Myers Squibb
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RecruitingSan Diego, CALIFORNIANCT06679855

Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

The goal of this Phase 3, randomized, masked clinical trial is to is to find out whether milrinone, when given to infants after PDA closure, will help the heart work better by supplying oxygen to the ...

316 participants
NICHD Neonatal Research Network
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RecruitingSan Diego, CALIFORNIANCT05960929

InfasurfAeroâ„¢ Versus Sham Treatment in Preterm Newborns With RDS

The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give I...

220 participants
ONY
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RecruitingSan Diego, CALIFORNIANCT06914609

REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

The purpose of this study is to evaluate the efficacy and safety of ION582 in children and adults with Angelman syndrome caused by a deletion or mutation of the UBE3A gene....

210 participants
Ionis Pharmaceuticals, Inc.
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RecruitingSan Diego, CALIFORNIANCT06366464

A Study of Pitolisant in Patients With Prader-Willi Syndrome

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome. The ...

134 participants
Harmony Biosciences Management, Inc.
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RecruitingSan Diego, CALIFORNIANCT04696029

DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

Difluoromethylornithine (DFMO) will be used in an open label, multicenter, study as Maintenance Therapy for Molecular High Risk/Very High Risk and Relapsed/Refractory Medulloblastoma....

118 participants
Giselle Sholler
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RecruitingSan Diego, CALIFORNIANCT06500481

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

This phase III trial compares proton craniospinal irradiation (pCSI) to involved-field radiation therapy (IFRT) for the treatment of breast or non-small cell lung cancer that has spread from where it ...

115 participants
NRG Oncology
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RecruitingSan Diego, CALIFORNIANCT06144645

A Clinical Evaluation of Non-Invasive Vagus Nerve Stimulation for Temper Outbursts in People With PWS

The goal of the VNS4PWS clinical study is to test the efficacy, safety, and acceptability of transcutaneous vagus nerve stimulation (tVNS) treatment in people with PWS....

102 participants
Foundation for Prader-Willi Research
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RecruitingSan Diego, CALIFORNIANCT07002034

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

The purpose of this study is to determine if treatment with a single dose of RE104 for Injection reduces depressive symptoms or depressive symptoms mixed with anxiety symptoms in participants with Adj...

100 participants
Reunion Neuroscience Inc
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RecruitingSan Diego, CALIFORNIANCT07197034

The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) Trial

The goal of this clinical trial is to learn if ARD-101 works to treat hyperphagia-related behavior in patients with Prader-Willi syndrome (PWS) when used in a long term setting. It will also teach us ...

90 participants
Aardvark Therapeutics, Inc.
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RecruitingSan Diego, CALIFORNIANCT05035030

Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome

The purpose of this study is to assess the long-term safety and effectiveness of odevixibat in participants with Alagille syndrome (ALGS). The participants of this study will have ALGS a rare genetic...

70 participants
Albireo, an Ipsen Company
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RecruitingSan Diego, CALIFORNIANCT05127226

HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

The purpose of this study is to evaluate the safety and tolerability of ascending doses of ION582 administered intrathecally in participants with Angelman syndrome....

70 participants
Ionis Pharmaceuticals, Inc.
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RecruitingSan Diego, CALIFORNIANCT05295433

An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705

The primary objective of this study is to evaluate the long-term safety of mRNA-3705 administered to participants with isolated methylmalonic acidemia (MMA) due to methylmalonyl-coenzyme A mutase (MUT...

63 participants
ModernaTX, Inc.
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RecruitingSan Diego, CALIFORNIANCT06912633

Safety of a Single, Intravitreal Injection of 8.8M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)

This study evaluates the safety of a single injection of jCell (famzeretcel) comprising 8.8 million (8.8M) retinal progenitor cells over a six-month study period in a cohort of adult subjects with RP....

60 participants
jCyte, Inc
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RecruitingSan Diego, CALIFORNIANCT06430385

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

The primary purpose of this study is to evaluate the safety and tolerability of ION440....

48 participants
Ionis Pharmaceuticals, Inc.
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RecruitingSan Diego, CALIFORNIANCT05521438

Safety, Tolerability and Efficacy of QRX003 Lotion in Subjects With Netherton Syndrome

This study has been designed to determine the safety, tolerability and efficacy of QRX003 lotion 2%, 4% QAM or 4% BID in subjects with Netherton Syndrome (NS) in comparison to vehicle...

30 participants
Quoin Pharmaceuticals
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RecruitingSan Diego, CALIFORNIANCT07157787

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

The primary objective of this study is to evaluate the efficacy of ALXN1920 compared with placebo in participants with PMN who are at a high risk for disease progression using 24-hour urine protein cr...

30 participants
Alexion Pharmaceuticals, Inc.
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RecruitingSan Diego, CALIFORNIANCT05789056

Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome

To assess the safety, tolerability, and efficacy of QRX003 lotion (4%) when added to standard of care treatment regimen, including systemic therapy in subjects with Netherton syndrome...

20 participants
Quoin Pharmaceuticals
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RecruitingSan Diego, CALIFORNIANCT05494593

A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)

The main aim of this study is to evaluate the ability of a prophylactic immune tolerizing regimen (ITR) to prevent or reduce the development of high titer anti-idursulfase antibodies in treatment-naïv...

5 participants
Takeda
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About Myalgic Encephalomyelitis Clinical Trials in San Diego

Myalgic encephalomyelitis (ME/CFS) is a complex, chronic illness characterized by profound fatigue, post-exertional malaise, cognitive impairment, and sleep dysfunction. It affects millions worldwide and has no definitive diagnostic test or cure. Research is exploring immune, metabolic, and neurological mechanisms.

There are currently 23 myalgic encephalomyelitis clinical trials recruiting participants in San Diego, CALIFORNIA. These studies are seeking a combined 4,047 participants. Research is being sponsored by Bristol-Myers Squibb, Janssen Pharmaceutica N.V., Belgium, CinPhloro Pharma, LLC and 16 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myalgic Encephalomyelitis Clinical Trials in San Diego — FAQ

Are there myalgic encephalomyelitis clinical trials in San Diego?

Yes, there are 23 myalgic encephalomyelitis clinical trials currently recruiting in San Diego, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Diego?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you about next steps.

Are clinical trials in San Diego free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Diego studies also compensate for your time and travel.

What myalgic encephalomyelitis treatments are being tested?

The 23 active trials in San Diego are testing new therapies including novel drugs, biologics, and treatment approaches for myalgic encephalomyelitis.

Data updated March 2, 2026 from ClinicalTrials.gov