San Diego, CALIFORNIA8 Active Studies

Ulcerative Colitis Clinical Trials in San Diego, CALIFORNIA

Find 8 actively recruiting ulcerative colitis clinical trials in San Diego, CALIFORNIA. Connect with local research sites and explore new treatment options.

8
Active Trials
7
Sponsors
2,671
Enrolling

Recruiting Ulcerative Colitis Studies in San Diego

RecruitingSan Diego, CALIFORNIANCT03519945

A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

This study is designed to evaluate the long-term efficacy and safety of mirikizumab in participants with moderately to severely active ulcerative colitis (UC). The study will last up to 3 years. Parti...

1,063 participants
Eli Lilly and Company
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RecruitingSan Diego, CALIFORNIANCT06880744

A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine).This study will evaluate how safe and ef...

530 participants
AbbVie
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RecruitingSan Diego, CALIFORNIANCT06589986

A Study to Assess the Efficacy and Safety of Afimkibart (Also Known as RO7790121) for Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

This Phase III, multicenter, double-blind, placebo-controlled, treat-through study will evaluate the efficacy and safety of Afimkibart (RO7790121) compared with placebo in participants with moderately...

400 participants
Hoffmann-La Roche
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RecruitingSan Diego, CALIFORNIANCT05442567

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

The study is an extension of two parent studies (MLN0002-3024 \[NCT04779307\] and MLN0002-3025 \[NCT04779320\]). Participants must have participated in one of the previous studies. The purpose of this...

240 participants
Takeda
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RecruitingSan Diego, CALIFORNIANCT06290934

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

The goal of this study is to learn if GS-1427 is effective in treating participants with moderate to severe ulcerative colitis. The study will compare participants in different treatment groups treate...

228 participants
Gilead Sciences
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RecruitingSan Diego, CALIFORNIANCT05011149

Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCT

Background: Among preterm infants, those born at a gestational age less than 26 weeks are considered the most vulnerable with a high risk of short- and long-term health problems that include chronic l...

100 participants
IWK Health Centre
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RecruitingSan Diego, CALIFORNIANCT05784246

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis

The main purpose of this study is to investigate efficacy, pharmacokinetics and safety of the drug in pediatric participants with moderately to severely active ulcerative colitis (UC)....

60 participants
Eli Lilly and Company
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RecruitingSan Diego, CALIFORNIANCT06109441

Efficacy/Safety of ALTB-268 in Subjects w/Moderately to Severely Active UC Refractory to Biologics

ALTB-268-201 is a Phase 2a, multicenter, single arm, multiple-dose, open-label study evaluating the efficacy and safety of ALTB-268 in subjects with moderately to severely active UC. The study consist...

50 participants
AltruBio Inc.
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About Ulcerative Colitis Clinical Trials in San Diego

Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the innermost lining of the colon and rectum. It typically presents with bloody diarrhea, abdominal pain, and urgency. Treatment includes aminosalicylates, corticosteroids, immunosuppressants, and biologics.

There are currently 8 ulcerative colitis clinical trials recruiting participants in San Diego, CALIFORNIA. These studies are seeking a combined 2,671 participants. Research is being sponsored by Eli Lilly and Company, AbbVie, Hoffmann-La Roche and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ulcerative Colitis Clinical Trials in San Diego — FAQ

Are there ulcerative colitis clinical trials in San Diego?

Yes, there are 8 ulcerative colitis clinical trials currently recruiting in San Diego, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Diego?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you about next steps.

Are clinical trials in San Diego free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Diego studies also compensate for your time and travel.

What ulcerative colitis treatments are being tested?

The 8 active trials in San Diego are testing new therapies including novel drugs, biologics, and treatment approaches for ulcerative colitis.

Data updated March 2, 2026 from ClinicalTrials.gov