47 Osteogenesis Imperfecta Clinical Trials in San Francisco, CA (2026)

Q: How do I join a clinical trial in San Francisco?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you.

Recruiting Osteogenesis Imperfecta Studies in San Francisco

NCT02418442Recruiting

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

Continuation of the CARRA Registry as described in the protocol will support data collection on patients with pediatric-onset rheumatic diseases. The CARRA Registry will form the basis for future CARR...

San Francisco, CA20,000 participantsDuke University

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NCT01750619Recruiting

Clinical Outcomes of the Endoscopic Resection of Premalignant and Malignant Gastrointestinal Lesions

To evaluate clinical outcome for patients receiving treatment of suspected premalignant and malignant gastrointestinal lesions at Interventional Endoscopy Services. The primary outcome is curative end...

San Francisco, CA8,000 participantsCalifornia Pacific Medical Center Research Institute

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NCT03013998Recruiting

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

This screening and multi-sub-study Phase 1b/2 trial will establish a method for genomic screening followed by assigning and accruing simultaneously to a multi-study "Master Protocol (BAML-16-001-M1)."...

San Francisco, CAPHASE23,000 participantsBeat AML, LLC

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NCT04216732Recruiting

Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management

This study utilizes a multi-institutional registry to describe the natural history of medullary thyroid cancer that has spread from where it first started to nearby tissue, lymph nodes, or distant par...

San Francisco, CA2,030 participantsM.D. Anderson Cancer Center

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NCT04098445Recruiting

TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

Hematopoietic stem cell transplant (HSCT) is an effective but toxic therapy and pulmonary morbidity affects as many as 25% of children receiving transplant. Early pulmonary injury includes diffuse alv...

San Francisco, CA2,000 participantsChildren's Hospital Medical Center, Cincinnati

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NCT06465810Recruiting

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

The MaesTTRo study aims to enroll a global cohort of patients with transthyretin (ATTR) amyloidosis to longitudinally observe the natural course of the disease and describe real-world treatment patter...

San Francisco, CA1,850 participantsAstraZeneca

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NCT07207811Recruiting

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

This study will find out if a new medicine called NNC6019-0001 can help reduce the risk of heart-related death and illness in participants with a condition called transthyretin amyloid cardiomyopathy ...

San Francisco, CAPHASE31,280 participantsNovo Nordisk A/S

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NCT04375033Recruiting

A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

VA-BRAVE will determine whether a 28-day long-acting injectable sub-cutaneous (in the belly area) formulation of buprenorphine at a target dose of 300mg is superior in retaining Veterans in opioid tre...

San Francisco, CAPHASE4952 participantsVA Office of Research and Development

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NCT06629272Recruiting

Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing

The proposed study focuses on testing a novel adapted evidence-based multilevel intervention, Deprescribing Thyroid Hormone In Older Adults (D-THIO), to support thyroid hormone deprescribing (dose de-...

San Francisco, CANA900 participantsUniversity of Michigan

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NCT07223814Recruiting

Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

The current standard of care treatment for adult patients with acute myeloid leukemia (AML) consists of chemotherapy and, if indicated, donor stem cell transplantation. Bleximenib blocks the interact...

San Francisco, CAPHASE3875 participantsStichting Hemato-Oncologie voor Volwassenen Nederland

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NCT07585266Recruiting

A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline)

Gastrointestinal Stromal Tumour (GIST) is a soft tissue tumour that develops in the digestive system, most often in the stomach or small intestine. It is caused by changes in certain proteins that cau...

San Francisco, CAPHASE3800 participantsGlaxoSmithKline

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NCT06323824Recruiting

Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.

The purpose of this clinical trial is to compare the effectiveness of office-based methadone with pharmacy administration and/or dispensing to office-based buprenorphine for the treatment of opioid us...

San Francisco, CAPHASE4600 participantsYale University

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NCT06563895Recruiting

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque- like substance that accumulates in different orga...

San Francisco, CAPHASE3587 participantsEidos Therapeutics, a BridgeBio company

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NCT05865301Recruiting

Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

To use a consistent and standardized platform to retrospectively and prospectively study children and young adults with B cell malignancies receiving Immunotherapy, blinatumomab and/or inotuzumab ozog...

San Francisco, CA500 participantsStanford University

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NCT05208047Recruiting

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

This is a Phase 3, open-label, international, multicenter study of CGT9486 in combination with sunitinib. This is a multi-part study that will enroll approximately 482 patients. Part 1 consists of two...

San Francisco, CAPHASE3482 participantsCogent Biosciences, Inc.

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NCT07420283Recruiting

A Study of Brenipatide in Participants With Opioid Use Disorder

The purpose of this study is to see if brenipatide, when compared to placebo, is safe and effective for participants with opioid use disorder, when used with buprenorphine with or without naloxone. T...

San Francisco, CAPHASE2465 participantsEli Lilly and Company

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NCT07218926Recruiting

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

The purpose of this study is to find out if a new drug, called IDRX-42 (also known as GSK6042981), is effective in treating adults with a type of cancer called Gastrointestinal Stromal Tumors (GIST) w...

San Francisco, CAPHASE3450 participantsGlaxoSmithKline

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NCT06397677Recruiting

Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease

A study to identify patients with Rheumatoid Arthritis - Associated Interstitial Lung Disease (RA-ILD) that are at the highest risk for progression. The goal of the investigators is to recruit a grou...

San Francisco, CA450 participantsUniversity of Colorado, Denver

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NCT06652438Recruiting

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

Treatment of patients with newly diagnosed AML who are not eligible for intensive chemotherapy has remained an area of high unmet medical need. The combination therapy with two medicines, azacitidine ...

San Francisco, CAPHASE3448 participantsStichting Hemato-Oncologie voor Volwassenen Nederland

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NCT05554406Recruiting

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with...

San Francisco, CAPHASE2335 participantsNational Cancer Institute (NCI)

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NCT06872190Recruiting

Using Clinical Decision Support to Provide Social Risk-Informed Care for Opioid Use Disorder in the Emergency Department

The overarching goal of this proposal is to integrate patient social risk information into an existing electronic health record (EHR)-based clinical decision support (CDS) tool (CDSv1) to facilitate e...

San Francisco, CANA300 participantsUniversity of California, San Francisco

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NCT07573150Recruiting

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

This study will evaluate whether quantitative pupillometry measurements can be used to identify children at risk for postoperative opioid-induced respiratory depression (OIRD) following tonsillectomy....

San Francisco, CA300 participantsNeurOptics Inc

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NCT02074839Recruiting

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

The purpose of this Phase I, multicenter study is to evaluate the safety, pharmacokinetics, pharmacodynamics and clinical activity of AG-120 in advanced hematologic malignancies that harbor an IDH1 mu...

San Francisco, CAPHASE1291 participantsInstitut de Recherches Internationales Servier

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NCT06587100Recruiting

Wearable Activity Tracking to Curb Hospitalizations

This study is being done to collect patient generated health data to predict the risk of patients needing emergency department visits or hospitalization before, during. and after receiving radiation t...

San Francisco, CA260 participantsUniversity of California, San Francisco

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NCT06978725Recruiting

A Phase 2 Study of the Safety and Efficacy of Brepocitinib in Adults With Cutaneous Sarcoidosis (BEACON)

This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with cutaneous sarcoidosis....

San Francisco, CAPHASE2168 participantsPriovant Therapeutics, Inc.

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NCT07831317Recruiting

Multi-strain Probiotic Supplement for Digestive Comfort and Well-being in Healthy Women

This study looks at whether a daily probiotic supplement can help improve mild-to-moderate stomach and digestive symptoms, such as gas and bloating, in women who also experience symptoms commonly asso...

San Francisco, CANA160 participantsDaily Nouri

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NCT06143631Recruiting

Prescription of Letrozole for Uterine Myoma

The PLUM Study is a randomized, double-blinded, 2-arm, parallel-group, placebo-controlled trial is designed to compare the efficacy of letrozole versus placebo on leiomyoma-related symptoms and qualit...

San Francisco, CAPHASE4140 participantsUniversity of California, San Francisco

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NCT07753603Recruiting

Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)

The goal of this clinical trial is to evaluate the efficacy, safety, and tolerability of linsitinib in participants with moderate to severe Thyroid Eye Disease (TED)....

San Francisco, CAPHASE3130 participantsSling Therapeutics, Inc.

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NCT05183035Recruiting

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin \[GO\]) improves survival of children/adolescents/young adults wit...

San Francisco, CAPHASE3130 participantsPedAL BCU, LLC

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NCT06118086Recruiting

Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

The goal of this study is to determine the safety and antitumor effects of REM-422, a MYB mRNA degrader, in people with advanced Adenoid Cystic Carcinoma (ACC)...

San Francisco, CAPHASE1125 participantsRemix Therapeutics

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NCT05711667Recruiting

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

This phase III single arm trial determines whether taking prophylactic letermovir will reduce the likelihood of infection with cytomegalovirus (CMV) in children and adolescents after stem cell transpl...

San Francisco, CAPHASE3105 participantsChildren's Oncology Group

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NCT06672146Recruiting

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

This phase II MyeloMATCH treatment trial studies how well ASTX727 and venetoclax plus enasidenib works compared to ASTX727 and venetoclax alone for the treatment of older patients with newly diagnosed...

San Francisco, CAPHASE293 participantsNational Cancer Institute (NCI)

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NCT07081646Recruiting

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

Open-label Phase 1b/2 study with primary objective of this study is to evaluate the safety, tolerability and efficacy of AZD0120 in participants with light chain (AL) amyloidosis....

San Francisco, CAPHASE191 participantsAlexion Pharmaceuticals, Inc.

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NCT07407777Recruiting

Evaluation of Gut-Related Well-Being and Mood Effects of a Daily Nutritional Food Ingredient From the Co-Fermentation of Fungal Mycelium (Pleurotus Pulmonarius) and Microalgae (Chlorella Vulgaris)

The purpose of the study is to evaluate the gut-related well-being and mood effects of a food ingredient obtained from the co-fermentation of oyster mushroom mycelium (Pleurotus pulmonarius), microalg...

San Francisco, CANA80 participantsKoralo GmbH

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NCT06961084Recruiting

Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer

Persons diagnosed with thyroid cancer are often treated initially with a thyroidectomy, which is followed by ablation using Iodine-131, a therapy which has been shown to be effective and safe. Imaging...

San Francisco, CAPHASE262 participantsThomas Hope

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NCT02923011Recruiting

Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas

Osteoid osteomas are painful, benign bone tumors that occur most frequently in young males between ages 10 and 20 years. The goal of the proposed study is based on the premise that MRgFUS is noninferi...

San Francisco, CAPHASE356 participantsMatthew Bucknor

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NCT07421596Recruiting

An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System

This clinical research study is being conducted to evaluate gut and digestive health before and after the use of a dietary supplement system over an eight-week period. Gut and digestive health play a...

San Francisco, CANA50 participantsSF Research Institute, Inc.

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NCT06201416Recruiting

Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis

This study will test the safety and effects of SBT777101 when given as a single dose to subjects with rheumatoid arthritis. It is the first study of this treatment being done in humans. Increasing dos...

San Francisco, CAPHASE148 participantsSonoma Biotherapeutics, Inc.

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NCT07123038Recruiting

A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic

To assess the emergence, type, severity, and potential causality of delayed adverse events following administration of a gene-modified Treg therapeutic....

San Francisco, CA36 participantsSonoma Biotherapeutics, Inc.

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NCT06247787Recruiting

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

This phase I trial tests the safety, side effects, and best dose of imetelstat in combination with fludarabine and cytarabine in treating patients with acute myeloid leukemia (AML), myelodysplastic sy...

San Francisco, CAPHASE136 participantsChildren's Oncology Group

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NCT05024929Recruiting

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

Papillary thyroid cancer (PTC) is a common type of differentiated thyroid cancer (DTC) in children and represents the second most common cancer in adolescent females. Recently targeted drugs that bloc...

San Francisco, CA32 participantsChildren's Hospital of Philadelphia

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NCT04883671Recruiting

Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

The aim of this study is to learn whether the early initiation of a specialized and focused type of radiation called stereotactic body radiation therapy (SBRT) will impact the progression of advanced ...

San Francisco, CANA32 participantsDana-Farber Cancer Institute

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NCT07447076Recruiting

Study of Novel Therapies for Young People With Recurrent/Progressive Atypical Teratoid Rhabdoid Tumor (ATRT)

This is a multi-treatment arm study that will be conducted through the Pacific Pediatric Neuro-oncology Consortium (PNOC).The study will assess the safety and efficacy of novel therapies and combinato...

San Francisco, CAPHASE229 participantsSabine Mueller, MD, PhD

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NCT07054801Recruiting

IA Lidocaine and Methylprednisolone for Headache Associated With Subarachnoid Hemorrhage

Subarachnoid hemorrhage (SAH) is a type of bleeding around the brain that can cause sudden and severe headaches. These headaches can be debilitating and persist for weeks, significantly impacting a pa...

San Francisco, CAPHASE225 participantsDaniel Raper, MBBS

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NCT06458036Recruiting

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioacti...

San Francisco, CAPHASE213 participantsChildren's Hospital of Philadelphia

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NCT05783323Recruiting

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

San Francisco, CAPHASE213 participantsChildren's Hospital of Philadelphia

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NCT06961071Recruiting

Parathyroid Allotransplant for Treatment of Hypoparathyroidism

This study is being done to see if transplanting parathyroid tissue into the forearm will help hypo-parathyroid patients achieve parathyroid hormone (PTH) levels that would help normalize their serum ...

San Francisco, CAPHASE13 participantsPeter Stock

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About Osteogenesis Imperfecta Clinical Trials in San Francisco

Osteogenesis imperfecta is a group of genetic disorders mainly affecting the bones, causing them to break easily, often from little or no apparent cause. It is caused by defects in collagen production. Treatment includes bisphosphonates, physical therapy, and surgical rodding.

There are currently 47 osteogenesis imperfecta clinical trials recruiting participants in San Francisco, CA. These studies are seeking a combined 48,812 participants. Research is being sponsored by Duke University, California Pacific Medical Center Research Institute, Beat AML, LLC and 35 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Osteogenesis Imperfecta Clinical Trials in San Francisco — FAQ

Are there osteogenesis imperfecta clinical trials in San Francisco?

Yes, there are 47 osteogenesis imperfecta clinical trials currently recruiting in San Francisco, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What osteogenesis imperfecta treatments are being tested?

The 47 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for osteogenesis imperfecta.

Data updated October 19, 2026 from ClinicalTrials.gov