San Francisco, CALIFORNIA6 Active Studies

Head and Neck Cancer Clinical Trials in San Francisco, CALIFORNIA

Find 6 actively recruiting head and neck cancer clinical trials in San Francisco, CALIFORNIA. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
2,415
Enrolling

Recruiting Head and Neck Cancer Studies in San Francisco

RecruitingSan Francisco, CALIFORNIANCT06129864

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

The main purpose of this study is to assess the efficacy and safety of volrustomig compared to observation in participants with unresected locally advanced head and neck squamous cell carcinoma (LA-HN...

1,145 participants
AstraZeneca
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RecruitingSan Francisco, CALIFORNIANCT04892173

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

This is a global, open-label, randomized, 2-arm, Investigator's choice Phase 3 (Pivotal Stage) study to investigate the efficacy and safety of JNJ-90301900 (NBTXR3) / radiation therapy (RT)±cetuximab ...

500 participants
Johnson & Johnson Enterprise Innovation Inc.
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RecruitingSan Francisco, CALIFORNIANCT06496178

A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients

This is a phase 3 open-label, randomized, controlled, multicenter study to compare petosemtamab vs investigator's choice monotherapy in HNSCC patients for the second- and third-line treatment of incur...

500 participants
Merus N.V.
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RecruitingSan Francisco, CALIFORNIANCT03480971

Treatment of Radiation and Cisplatin Induced Toxicities with Tempol

A 10 week trial to assess the ability of Tempol to prevent and/or reduce toxicities associated with cisplatin and radiation treatment in head and neck cancer patients. Over the course of the 10 week t...

120 participants
Matrix Biomed, Inc.
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RecruitingSan Francisco, CALIFORNIANCT06457503

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

This study aims to investigate toripalimab with chemotherapy in participants with nasopharyngeal cancer....

100 participants
Coherus Oncology, Inc.
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RecruitingSan Francisco, CALIFORNIANCT06064097

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

This phase II trial tests effects of nivolumab in combination with chemotherapy drugs prior to radiation therapy patients with nasopharyngeal carcinoma (NPC). Immunotherapy with monoclonal antibodies,...

50 participants
National Cancer Institute (NCI)
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About Head and Neck Cancer Clinical Trials in San Francisco

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 6 head and neck cancer clinical trials recruiting participants in San Francisco, CALIFORNIA. These studies are seeking a combined 2,415 participants. Research is being sponsored by AstraZeneca, Johnson & Johnson Enterprise Innovation Inc., Merus N.V. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in San Francisco — FAQ

Are there head and neck cancer clinical trials in San Francisco?

Yes, there are 6 head and neck cancer clinical trials currently recruiting in San Francisco, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 6 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated March 2, 2026 from ClinicalTrials.gov