16 Breast Cancer Clinical Trials in Scottsdale, AZ (2026)

Q: How do I join a clinical trial in Scottsdale?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Scottsdale research site will contact you.

Recruiting Breast Cancer Studies in Scottsdale

NCT01042379Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

The purpose of this study is to further advance the ability to practice personalized medicine by learning which new drug agents are most effective with which types of breast cancer tumors and by learn...

Scottsdale, AZPHASE25,000 participantsQuantumLeap Healthcare Collaborative

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NCT06492616Recruiting

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

The primary goal of this study is to evaluate the effectiveness of elacestrant versus standard endocrine therapy in participants with node-positive, Estrogen Receptor-positive (ER+), Human Epidermal G...

Scottsdale, AZPHASE34,220 participantsStemline Therapeutics, Inc.

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NCT04475640Recruiting

Cancer Genetic Testing in Ethnic Populations

This clinical trial examines the integration of cancer genetic testing in various ethnic populations. Studying individuals and families at risk of cancer may help identify cancer genes and other perso...

Scottsdale, AZNA1,800 participantsMayo Clinic

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NCT07214532Recruiting

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

The purpose of this study is to evaluate the efficacy and safety of ctDNA-guided initiation of CDK4/6 inhibitor therapy using the Signatera™ Designed on Genome test (referred to as "Signatera Genome")...

Scottsdale, AZNA725 participantsNatera, Inc.

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NCT05696626Recruiting

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

The goal of this clinical trial is to assess the efficacy, safety and tolerability of the combination of lasofoxifene and abemaciclib compared to fulvestrant and abemaciclib for the treatment of pre- ...

Scottsdale, AZPHASE3600 participantsSermonix Pharmaceuticals Inc.

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NCT06377852Recruiting

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

The purpose of this study is to generate evidence on an alternative dosing strategy for CDK4/6 inhibitors to help more patients with Metastatic Breast Cancer (MBC) (age ≥ 65 years) tolerate side effec...

Scottsdale, AZPHASE3500 participantsAmerican Society of Clinical Oncology

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NCT07062965Recruiting

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

The purpose of this study is to learn about the safety and effects of the study medicine PF-07248144 when given along with fulvestrant for the possible treatment of HR-positive, HER2-negative advanced...

Scottsdale, AZPHASE3400 participantsPfizer

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NCT05896189Recruiting

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

This Phase III trial will examine the efficacy of computerized cognitive training methods on perceived cognitive impairment in breast cancer survivors....

Scottsdale, AZNA386 participantsNRG Oncology

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NCT04606446Recruiting

Study of PF-07248144 in Advanced or Metastatic Solid Tumors

This is an open-label, multi center study to evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of PF-07248144 and early signs of clinical efficacy of PF-07248144 as a sin...

Scottsdale, AZPHASE2320 participantsPfizer

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NCT05856773Recruiting

Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy

The purpose of this research study is to learn more about the effects of using proton radiation therapy delivered over a shorter course of treatment (3 weeks) compared with a longer, standard course o...

Scottsdale, AZPHASE3276 participantsProton Collaborative Group

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NCT01766297Recruiting

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

The purpose of this research study is to compare the effects (good and bad) on women and their cancer using proton radiation therapy. This study is being done to see if proton radiation therapy will ...

Scottsdale, AZPHASE2132 participantsProton Collaborative Group

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NCT06635980Recruiting

Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

This phase II trial studies how well hypofractionated radiotherapy before (preoperative) or after (postoperative) breast surgery works in treating patients with different types of non-metastatic (has ...

Scottsdale, AZPHASE2120 participantsMayo Clinic

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NCT05557877Recruiting

Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

This phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) women planning to have a breast biopsy. Chronic inflammation may increase the ris...

Scottsdale, AZPHASE260 participantsMayo Clinic

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NCT06055881Recruiting

Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic Therapy

This study assesses if metastasis-directed radiation therapy (Stereotactic body radiation therapy - SBRT) can delay a change in systemic therapy, and if circulating tumor cells in the bloodstream can ...

Scottsdale, AZNA45 participantsMayo Clinic

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NCT06450873Recruiting

Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery

This phase II trial tests how well turkey tail mushroom (TTM) works in treating post-menopausal women with HER2-negative, estrogen receptor (ER)-positive breast cancer undergoing surgery. TTM is a com...

Scottsdale, AZPHASE240 participantsMayo Clinic

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NCT06525766Recruiting

Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer

This phase II trial evaluates the effect of capecitabine on tumor response using imaging and tumor markers to adjust dose (adaptive therapy) in patients with estrogen receptor (ER) positive, HER2 nega...

Scottsdale, AZPHASE235 participantsMayo Clinic

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About Breast Cancer Clinical Trials in Scottsdale

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 16 breast cancer clinical trials recruiting participants in Scottsdale, AZ. These studies are seeking a combined 14,659 participants. Research is being sponsored by QuantumLeap Healthcare Collaborative, Stemline Therapeutics, Inc., Mayo Clinic and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Scottsdale — FAQ

Are there breast cancer clinical trials in Scottsdale?

Yes, there are 16 breast cancer clinical trials currently recruiting in Scottsdale, AZ. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Scottsdale?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Scottsdale research site will contact you about next steps.

Are clinical trials in Scottsdale free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Scottsdale studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 16 active trials in Scottsdale are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated July 19, 2026 from ClinicalTrials.gov