Recruiting Sickle Cell Disease Studies in St Louis
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
This study is designed to estimate the efficacy and toxicity of familial HLA mismatched bone marrow transplants in patients with non-malignant disease who are less than 21 years of age and could benef...
Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease
This study is a first-in-human, single-arm, open-label Phase I/II study of nula-cel in approximately 15 participants, diagnosed with severe Sickle Cell Disease. The primary objective is to evaluate sa...
BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease
This is an open-label, single-arm, multicenter, Phase 1/2 study evaluating the safety and efficacy of the administration of autologous base edited CD34+ HSPCs (BEAM-101) in patients with severe SCD...
About Sickle Cell Disease Clinical Trials in St Louis
Sickle cell disease is a group of inherited blood disorders where abnormal hemoglobin causes red blood cells to become rigid and sickle-shaped. It causes pain crises, organ damage, and shortened life expectancy. Treatment includes hydroxyurea, blood transfusions, and gene therapy.
There are currently 3 sickle cell disease clinical trials recruiting participants in St Louis, MISSOURI. These studies are seeking a combined 59 participants. Research is being sponsored by Washington University School of Medicine, Kamau Therapeutics, Beam Therapeutics Inc.. Clinical trial participation is free and participants receive study-related medical care at no cost.
Sickle Cell Disease Clinical Trials in St Louis — FAQ
Are there sickle cell disease clinical trials in St Louis?
Yes, there are 3 sickle cell disease clinical trials currently recruiting in St Louis, MISSOURI. Browse the studies on this page to find one that fits.
How do I join a clinical trial in St Louis?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.
Are clinical trials in St Louis free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.
What sickle cell disease treatments are being tested?
The 3 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for sickle cell disease.
Data updated March 2, 2026 from ClinicalTrials.gov