5 Pancreatic Cancer Clinical Trials in St Louis, MO (2026)

Q: How do I join a clinical trial in St Louis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you.

Recruiting Pancreatic Cancer Studies in St Louis

NCT07644559Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic Cancer...

St Louis, MOPHASE2180 participantsVerastem, Inc.

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NCT05764720Recruiting

Stereotactic Adaptive Radiation Therapy of Borderline Resectable Pancreatic Cancer an Individualized Approach

This trial is a single-arm, prospective, multi-center clinical trial designed to demonstrate that stereotactic adaptive radiotherapy using an ablatively dosed (50Gy,5fx) for treatment of borderline-re...

St Louis, MONA134 participantsVarian, a Siemens Healthineers Company

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NCT07450859Recruiting

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

This is a Phase 2 study for nuzefatide pevedotin (BT5528) in adults with a specific type of pancreatic cancer called metastatic pancreatic ductal adenocarcinoma (PDAC) that has spread and worsened aft...

St Louis, MOPHASE239 participantsBicycleTx Limited

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NCT07126158Recruiting

Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma

Advanced pancreatic cancer patients receiving treatment of adaptive stereotactic body radiotherapy (SBRT) with concurrent and adjuvant defactinib plus avutometinib will have increased progression-free...

St Louis, MOPHASE236 participantsWashington University School of Medicine

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NCT06141031Recruiting

Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma

The survival rate for patients with pancreatic cancer remains at a dismal 10% or less at 5 years, and although trials integrating stereotactic body radiation therapy (SBRT) alone have shown improvemen...

St Louis, MOPHASE118 participantsWashington University School of Medicine

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About Pancreatic Cancer Clinical Trials in St Louis

Pancreatic cancer begins in the tissues of the pancreas and is often diagnosed at an advanced stage. It is one of the most challenging cancers to treat. Clinical trials are actively investigating new approaches including immunotherapy and combination regimens.

There are currently 5 pancreatic cancer clinical trials recruiting participants in St Louis, MO. These studies are seeking a combined 407 participants. Research is being sponsored by Verastem, Inc., Varian, a Siemens Healthineers Company, BicycleTx Limited and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pancreatic Cancer Clinical Trials in St Louis — FAQ

Are there pancreatic cancer clinical trials in St Louis?

Yes, there are 5 pancreatic cancer clinical trials currently recruiting in St Louis, MO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in St Louis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.

Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.

What pancreatic cancer treatments are being tested?

The 5 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for pancreatic cancer.

Data updated July 18, 2026 from ClinicalTrials.gov