4 Depression Clinical Trials in Upland, CA (2026)

Q: How do I join a clinical trial in Upland?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Upland research site will contact you.

Recruiting Depression Studies in Upland

NCT07076407Recruiting

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

X-NOVA3 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy in adult participants ...

Upland, CAPHASE3450 participantsXenon Pharmaceuticals Inc.

View Study Details

NCT06223880Recruiting

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

This is a randomized, double-blind, active-controlled, multi-center study to evaluate the efficacy of AXS-05, compared to bupropion, in preventing the relapse of depressive symptoms in subjects with m...

Upland, CAPHASE4350 participantsAxsome Therapeutics, Inc.

View Study Details

NCT06786624Recruiting

Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

The study will evaluate the efficacy of NBI-1065845 compared with placebo as an adjunctive treatment in participants with MDD on improving symptoms of depression....

Upland, CAPHASE3200 participantsNeurocrine Biosciences

View Study Details

NCT06547489Recruiting

GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder

The goal of this clinical trial is to learn if GATE-251 works to treat depression in adults. It will also learn about the safety of GATE-251. The main questions it aims to answer are: Does GATE-251 r...

Upland, CAPHASE2164 participantsSyndeio Biosciences, Inc

View Study Details

About Depression Clinical Trials in Upland

Depression (major depressive disorder) is a common and serious mood disorder that negatively affects how you feel, think, and handle daily activities. It affects over 280 million people globally. Treatment includes psychotherapy, antidepressant medications, and brain stimulation therapies.

There are currently 4 depression clinical trials recruiting participants in Upland, CA. These studies are seeking a combined 1,164 participants. Research is being sponsored by Xenon Pharmaceuticals Inc., Axsome Therapeutics, Inc., Neurocrine Biosciences and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Depression Clinical Trials in Upland — FAQ

Are there depression clinical trials in Upland?

Yes, there are 4 depression clinical trials currently recruiting in Upland, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Upland?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Upland research site will contact you about next steps.

Are clinical trials in Upland free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Upland studies also compensate for your time and travel.

What depression treatments are being tested?

The 4 active trials in Upland are testing new therapies including novel drugs, biologics, and treatment approaches for depression.

Data updated July 22, 2026 from ClinicalTrials.gov