Aurora, CONCT04262466Now EnrollingIRB Ready

I cannot determine the primary medical condition from the provided information. The data only lists drug combinations and treatments, but does not specify what medical condition or disease these treatments are targeting. The brief summary appears to be incomplete (showing only "localhost:3000/trial/"), and there are no keywords provided that would indicate the underlying health condition being studied. Clinical Trial in Aurora, CO

Access cutting-edge i cannot determine the primary medical condition from the provided information. the data only lists drug combinations and treatments, but does not specify what medical condition or disease these treatments are targeting. the brief summary appears to be incomplete (showing only "localhost:3000/trial/"), and there are no keywords provided that would indicate the underlying health condition being studied. treatment through this clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by Immunocore Ltd

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Access i cannot determine the primary medical condition from the provided information. the data only lists drug combinations and treatments, but does not specify what medical condition or disease these treatments are targeting. the brief summary appears to be incomplete (showing only "localhost:3000/trial/"), and there are no keywords provided that would indicate the underlying health condition being studied. specialists at no cost

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This study follows strict safety protocols and ethical guidelines

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All study-related i cannot determine the primary medical condition from the provided information. the data only lists drug combinations and treatments, but does not specify what medical condition or disease these treatments are targeting. the brief summary appears to be incomplete (showing only "localhost:3000/trial/"), and there are no keywords provided that would indicate the underlying health condition being studied. treatment provided free

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Check if you qualify for this i cannot determine the primary medical condition from the provided information. the data only lists drug combinations and treatments, but does not specify what medical condition or disease these treatments are targeting. the brief summary appears to be incomplete (showing only "localhost:3000/trial/"), and there are no keywords provided that would indicate the underlying health condition being studied. clinical trial in Aurora, CO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This I cannot determine the primary medical condition from the provided information. The data only lists drug combinations and treatments, but does not specify what medical condition or disease these treatments are targeting. The brief summary appears to be incomplete (showing only "localhost:3000/trial/"), and there are no keywords provided that would indicate the underlying health condition being studied. Study in Aurora

Brenetafusp (IMC-F106C) is an immune-mobilizing monoclonal T cell receptor against cancer (ImmTAC ยฎ) designed for the treatment of cancers positive for the tumor-associated antigen PRAME. This is a first-in-human trial designed to evaluate the safety and efficacy of brenetafusp in adult participants who have the appropriate HLA-A2 tissue marker and whose cancer is positive for PRAME.

Sponsor: Immunocore Ltd

Who Can Participate

Inclusion Criteria

ECOG PS 0 or 1 2. HLA-A\*02:01 positive 3. PRAME positive tumor 4. Relapsed from, refractory to, or intolerant of standard therapies; or, in combination with standard therapies 5. If applicable, must agree to use highly effective contraception

Exclusion Criteria

Symptomatic or untreated central nervous system metastasis 2. Recent bowel obstruction 3. Ongoing ascites or effusion requiring recent drainages 4. Significant immune-mediated adverse event with prior immunotherapy (Participants in checkpoint inhibitor combination treatment) 5. Inadequate washout from prior anticancer therapy 6. Significant ongoing toxicity from prior anticancer treatment 7. Out-of-range laboratory values 8. Clinically significant lung, heart, or autoimmune disease 9. Ongoing requirement for immunosuppressive treatment 10. Prior solid organ or bone marrow transplant 11. Active hepatitis B virus (HBV), hepatitis C virus (HCV), or human immunodeficiency virus (HIV) infection 12. Sign

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT04262466) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

I cannot determine the primary medical condition from the provided information. The data only lists drug combinations and treatments, but does not specify what medical condition or disease these treatments are targeting. The brief summary appears to be incomplete (showing only "localhost:3000/trial/"), and there are no keywords provided that would indicate the underlying health condition being studied. Treatment Options in Aurora, CO

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Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced i cannot determine the primary medical condition from the provided information. the data only lists drug combinations and treatments, but does not specify what medical condition or disease these treatments are targeting. the brief summary appears to be incomplete (showing only "localhost:3000/trial/"), and there are no keywords provided that would indicate the underlying health condition being studied. specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

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