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Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)

Sponsored by Major Extremity Trauma Research Consortium

Quick Self-Assessment

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Current Status

Recruiting

Auto-verified from ClinicalTrials.gov

Verified Feb 27, 2026

Phase

Clinical Trial

Sponsor

Major Extremity Trauma Research Consortium

Enrollment Target

40

Start Date

Jun 2023

๐Ÿ“Š
1 of 40 participants interested
3% interest

Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

The overall objective of this study is to determine the safety of PEG fusion when used with primary repair or reconstruction in patients with an acute upper extremity peripheral nerve injury. PEG is safe and effective for extending the half-life of circulating pharmaceutical products, when used in conjunction with a topical hemostatic agent in surgical wounds, and when used as a colon cleanser for endoscopic surgical procedures.

Who Can Participate

Inclusion Criteria

Ages 18-80 2. Sustained a complete peripheral nerve injury resulting from upper extremity trauma presenting within 48 hours of injury 3. Involves injury or dysfunction to motor and/or sensory function of the axillary, radial, median, ulnar, or musculocutaneous nerve with injury localized between the proximal humerus and the distal flexion crease of the wrist 4. Involves a "mixed" nerve segment (i.e., involves a location of any of the above specified nerves that can be expected to have both sensory and motor axons present).

Exclusion Criteria

Patients beginning surgery within hours after injury. 2. Injury to the brachial plexus nerves 3. Injury to the nerves distal to the distal flexion crease of the wrist 4. Injury that involves a distal extension of the parent nerve that is considered sensory only (superficial radial nerve, lateral antebrachial cutaneous nerve, etc.) or the posterior interosseus or anterior interosseus nerve distal to the midpoint of the

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

๐Ÿ“‹

Study Type

INTERVENTIONAL

๐Ÿ‘ฅ

Target Enrollment

40 participants

๐ŸŽ‚

Age Range

18 Years - 80 Years

โšง

Gender

ALL

๐Ÿข

Sponsor

Major Extremity Trauma Research Consortium

Study Locations

Choose your preferred location or select flexible during enrollment

RECRUITING

Baltimore

Maryland

Location available
View Baltimore location page
RECRUITING

Baltimore

Maryland

Location available
View Baltimore location page
RECRUITING

Camden

New Jersey

Location available
View Camden location page
RECRUITING

Charlotte

North Carolina

Location available
View Charlotte location page
RECRUITING

York

Pennsylvania

Location available
View York location page
RECRUITING

San Antonio

Texas

Location available
View San Antonio location page
RECRUITING

Richmond

Virginia

Location available
View Richmond location page

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

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Looking for Based on the provided information, I cannot determine a primary patient-facing medical condition. The study title mentions "PEG Fusion" which appears to be a treatment technique, and the only condition listed is "DRUG:NTX-001" which is a drug identifier rather than a medical condition. Without additional clinical context or a proper medical indication, there is insufficient information to extract a patient-searchable condition. Treatment in Baltimore?

Join others in Maryland exploring innovative treatment options through clinical research

Based on the provided information, I cannot determine a primary patient-facing medical condition. The study title mentions "PEG Fusion" which appears to be a treatment technique, and the only condition listed is "DRUG:NTX-001" which is a drug identifier rather than a medical condition. Without additional clinical context or a proper medical indication, there is insufficient information to extract a patient-searchable condition. Treatment Options in Baltimore, Maryland

If you're searching for Based on the provided information, I cannot determine a primary patient-facing medical condition. The study title mentions "PEG Fusion" which appears to be a treatment technique, and the only condition listed is "DRUG:NTX-001" which is a drug identifier rather than a medical condition. Without additional clinical context or a proper medical indication, there is insufficient information to extract a patient-searchable condition. treatment in Baltimore, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Baltimore, Baltimore, Bethesda and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Based on the provided information, I cannot determine a primary patient-facing medical condition. The study title mentions "PEG Fusion" which appears to be a treatment technique, and the only condition listed is "DRUG:NTX-001" which is a drug identifier rather than a medical condition. Without additional clinical context or a proper medical indication, there is insufficient information to extract a patient-searchable condition.. All study-related care is provided at no cost to participants.

Local Sites
3 locations in Maryland
Now Enrolling
Up to 40 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Based on the provided information, I cannot determine a primary patient-facing medical condition. The study title mentions "PEG Fusion" which appears to be a treatment technique, and the only condition listed is "DRUG:NTX-001" which is a drug identifier rather than a medical condition. Without additional clinical context or a proper medical indication, there is insufficient information to extract a patient-searchable condition.?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Based on the provided information, I cannot determine a primary patient-facing medical condition. The study title mentions "PEG Fusion" which appears to be a treatment technique, and the only condition listed is "DRUG:NTX-001" which is a drug identifier rather than a medical condition. Without additional clinical context or a proper medical indication, there is insufficient information to extract a patient-searchable condition.

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Based on the provided information, I cannot determine a primary patient-facing medical condition. The study title mentions "PEG Fusion" which appears to be a treatment technique, and the only condition listed is "DRUG:NTX-001" which is a drug identifier rather than a medical condition. Without additional clinical context or a proper medical indication, there is insufficient information to extract a patient-searchable condition. Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT04789044. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.