73 Active Studies

ADHD Clinical Trials Near You

Find 73 actively recruiting adhd research studies near you. Connect with study sites, check eligibility, and explore new treatment options.

73
Active Trials
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15,786
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Recruiting Studies

RecruitingNCT06225596

Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

This is a global, multicenter, randomized, open-label study, with an adaptive design. The main objective of the study is to measure the efficacy and safety of BT8009 (zelenectide pevedotin) as monothe...

10 locations(Little Rock, Fullerton, Orange)
956 participants
BicycleTx Limited
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RecruitingNCT05538663

Intravesical BCG vs GEMDOCE in NMIBC

The study hypothesis is that BCG naïve non-muscle invasive bladder cancer (NMIBC) patients treated with intravesical Gemcitabine + Docetaxel (GEMDOCE) will result in a non-inferior event-free survival...

10 locations(Birmingham, Fairbanks, Gilbert)
870 participants
ECOG-ACRIN Cancer Research Group
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RecruitingNCT06876649

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

The master protocol study J2N-MC-JZNY provides a framework to enable the evaluation of the long-term safety and efficacy of pirtobrutinib after completion of clinical studies evaluating pirtobrutinib....

10 locations(Miami, Sarasota, Atlanta)
787 participants
Eli Lilly and Company
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RecruitingNCT02138734

A Study of Intravesical BCG in Combination With ALT-803 in Patients With Non-Muscle Invasive Bladder Cancer

This is a Phase Ib/IIb, randomized, two-cohort, open-label, multicenter study of intravesical N-803 plus BCG versus BCG alone, in BCG naïve patients with high-grade NMIBC....

10 locations(Birmingham, Anchorage, Little Rock)
596 participants
ImmunityBio, Inc.
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RecruitingNCT06319820

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

The main purpose of this study is to compare the disease-free survival between participants receiving treatment with TAR-210 versus investigator's choice of intravesical chemotherapy for treatment of ...

10 locations(Little Rock, Los Alamitos, Los Angeles)
560 participants
Janssen Research & Development, LLC
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RecruitingNCT06703476

A Study of Surgical Techniques During Cystectomy

The purpose of this study is to look at two standard surgical techniques used during a radical cystectomy and see whether they influence outcomes such as length of stay in the hospital and infections ...

7 locations(Basking Ridge, Middletown, Montvale)
530 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNCT05916339

AWARE: Management of ADHD in Autism Spectrum Disorder

This study is a pragmatic clinical trial examining the comparative effectiveness of two stimulant medications (methylphenidate and amphetamine) in the treatment of ADHD in children and adolescents wit...

10 locations(Irvine, Los Angeles, Portland)
500 participants
Daniel Coury
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RecruitingNCT03781752

Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD

The study team will determine the association between d,l-methylphenidate (MPH) therapeutic outcomes in ADHD patients and genetic variants of CES1 and reveal key associations between CES1 genotypes an...

4 locations(Gainesville, New York, Cincinnati)
500 participants
Icahn School of Medicine at Mount Sinai
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RecruitingNCT06510374

Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer

A phase 3b, Randomized, Controlled Trial of Nadofaragene Firadenovec vs. Observation in Participants with Intermediate Risk Non-Muscle Invasive Bladder Cancer (IR NMIBC)...

10 locations(Mobile, Mobile, Fresno)
454 participants
Ferring Pharmaceuticals
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RecruitingNCT06032559

Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment

This hybrid implementation-effectiveness trial will evaluate Mindfulness-Oriented Recovery Enhancement (MORE) for patients with opioid use disorder receiving methadone treatment (MT). The investigator...

2 locations(New Brunswick, Salt Lake City)
450 participants
Rutgers, The State University of New Jersey
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RecruitingNCT06033599

Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement

The purpose of this study is to 1) examine barriers and facilitators to implementation of MI and MORE for polysubstance use and evaluate strategies for optimizing training, fidelity, and clinic uptake...

2 locations(New Brunswick, Salt Lake City)
420 participants
Rutgers, The State University of New Jersey
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RecruitingNCT05911295

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

This study will enroll participants with urothelial cancer (UC). UC can include cancer of the bladder, kidney, or the tubes that carry pee through the body (ureter, urethra). This study will try to fi...

10 locations(Gilbert, Gilbert, Alhambra)
400 participants
Seagen, a wholly owned subsidiary of Pfizer
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RecruitingNCT04879329

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

This study is being done to see if a drug called disitamab vedotin, alone or with pembrolizumab, works to treat HER2 expressing urothelial cancer. It will also test how safe the drug is for participan...

10 locations(Gilbert, Gilbert, Anaheim)
372 participants
Seagen, a wholly owned subsidiary of Pfizer
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RecruitingNCT06534983

A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (MIUC)

The main purpose of the study is to evaluate the efficacy of adjuvant treatment with autogene cevumeran plus nivolumab compared with nivolumab in participants with high risk MIUC. In this study parti...

10 locations(Springdale, Duarte, Riverside)
362 participants
Hoffmann-La Roche
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RecruitingNCT04752722

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

This study will evaluate the safety and efficacy of intravesical administration of EG-70 in the bladder and its effect on bladder tumors in patients with NMIBC. This study study consists of two phase...

10 locations(Birmingham, Scottsdale, Tucson)
350 participants
enGene, Inc.
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RecruitingNCT07000084

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

This phase III trial compares the effect of adding gemcitabine to intravesical Bacillus Calmette Guerin (BCG) versus intravesical BCG alone in patients with non-muscle invasive bladder cancer that has...

10 locations(Birmingham, Gilbert, Gainesville)
330 participants
Alliance for Clinical Trials in Oncology
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RecruitingNCT04561362

Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies

This study is a Phase I/II, multicenter, first-in-human, open-label dose-escalation study of BT8009 given as a single agent and in combination with pembrolizumab in participants with advanced solid tu...

10 locations(Denver, Ocala, Orlando)
329 participants
BicycleTx Limited
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RecruitingNCT06567743

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

This is a Phase 2, Multi-Arm, Multi-Cohort, Open-Label Study to Evaluate the Safety and Efficacy of Cretostimogene Grenadenorepvec in Participants with High-Risk Non-Muscle-Invasive Bladder Cancer....

10 locations(Phoenix, Tucson, Little Rock)
325 participants
CG Oncology, Inc.
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RecruitingNCT05544552

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of TYRA-300 in cancers with FGFR3 activating gene alterations, including lo...

10 locations(Ocala, Boston, Worcester)
310 participants
Tyra Biosciences, Inc
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RecruitingNCT06833073

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

Researchers are looking for new ways to treat people with high-risk non-muscle invasive bladder cancer (HR NMIBC). NMIBC is cancer in the tissue that lines the inside of the bladder but has not spread...

10 locations(Bakersfield, Los Alamitos, Los Angeles)
308 participants
Merck Sharp & Dohme LLC
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RecruitingNCT06973577

P3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety

Primary: To evaluate the efficacy of CTN in adults ages with ADHD and comorbid anxiety (AISRS) Key Secondary: To assess the efficacy of CTN in adults ages with ADHD and comorbid anxiety...

10 locations(Dothan, Little Rock, Rogers)
308 participants
Otsuka Pharmaceutical Development & Commercialization, Inc.
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RecruitingNCT04781140

Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

This study will evaluate the efficacy and safety of SPN-812 (viloxazine extended release) in children 4 to 5 years of age with ADHD....

10 locations(Saraland, Fayetteville, Little Rock)
286 participants
Supernus Pharmaceuticals, Inc.
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RecruitingNCT03609216

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

This phase II trial studies how well gemcitabine hydrochloride and cisplatin work in treating participants with invasive bladder urothelial cancer. Drugs used in chemotherapy, such as gemcitabine hydr...

10 locations(Fairbanks, Goodyear, Phoenix)
271 participants
Alliance for Clinical Trials in Oncology
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RecruitingNCT05316155

Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

The purpose of the study in Part 1 (dose escalation) and in Part 2 (dose expansion) is to determine the recommended Phase 2 dose(s) (RP2D\[s\]) and evaluate preliminary clinical efficacy. Part 3 (dose...

10 locations(Birmingham, Los Angeles, Lone Tree)
262 participants
Janssen Research & Development, LLC
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RecruitingNCT06211764

A Study of TAR-200 Versus Intravesical Chemotherapy in Participants With Recurrent High-Risk Non-Muscle-Invasive Bladder Cancer (HR-NMIBC) After Bacillus Calmette-Guérin (BCG)

The purpose of this study is to compare disease free survival (DFS) in participants with recurrence of papillary-only high-risk non-muscle-invasive bladder cancer (HR-NMIBC) within 1 year of last dose...

10 locations(Little Rock, Los Alamitos, Los Angeles)
250 participants
Janssen Research & Development, LLC
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RecruitingNCT06545955

A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

The pivotal phase 3 trial (rAd-IFN-CS 003) evaluating the efficacy of nadofaragene firadenovec showed that 55 (53.4%) of 103 subjects with CIS ± high-grade Ta/T1 achieved a complete response (CR) at 3...

10 locations(Los Angeles, Los Angeles, Orange)
250 participants
Ferring Pharmaceuticals
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RecruitingNCT06305767

A Clinical Study of Intismeran Autogene (V940) Treatment and Pembrolizumab in People With Bladder Cancer (V940-005/INTerpath-005)

Researchers are looking for new ways to treat people with high-risk muscle-invasive urothelial carcinoma (MIUC). Urothelial carcinoma is a type of bladder cancer that begins in cells that line the ins...

10 locations(Los Angeles, Orlando, Chicago)
230 participants
Merck Sharp & Dohme LLC
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RecruitingNCT05033028

Smartphones for Opiate Addiction Recovery

Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use du...

2 locations(Piscataway, New York)
225 participants
NYU Langone Health
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RecruitingNCT04421248

Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurobehavioral disorder in childhood. Children with ADHD struggle in school due to problems with attention and high leve...

2 locations(Baltimore, Cincinnati)
214 participants
Donald Gilbert, MD, MS, FAAN, FAAP
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RecruitingNCT06525571

Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection

Comparing white-light cystoscopy (WLC) and blue-light cystoscopy (BLC) in TURBT for high risk (HR) non-muscle invasive bladder cancer (NMIBC) patients is crucial to determine the most effective method...

2 locations(Washington D.C., Baltimore)
200 participants
Johns Hopkins University
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RecruitingNCT06051890

Assessing Optimal XRB Initiation Points in Jail

This application describes a 3-year, randomized controlled trial. Eligible, consenting adults (N=200) with existing sublingual buprenorphine (SLB) prescriptions who enter Middlesex County House of Cor...

4 locations(Boston, Springfield, New Brunswick)
200 participants
NYU Langone Health
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RecruitingNCT06431256

Efficacy, Safety & Pharmacokinetic (PK) Study of HLD200 in Children Aged 4-5 Years with ADHD

This study will evaluate the efficacy, safety and pharmacokinetics of HLD200 (20 mg and 40 mg) in children aged 4 to 5 years with ADHD....

10 locations(Dothan, Anaheim, Jacksonville)
168 participants
Ironshore Pharmaceuticals and Development, Inc
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RecruitingNCT04375813

Trial of Encapsulated Rapamycin (eRapa) for Bladder Cancer Prevention

eRapa (encapsulated rapamycin) will be investigated for secondary prevention in patients with diagnosed non-muscle invasive bladder cancer (NMIBC) through a phase II double-blind randomized controlled...

2 locations(Dallas, San Antonio)
166 participants
Robert Svatek
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RecruitingNCT06215144

Study to Evaluate NRCT-101SR in Pediatric Subjects with ADHD

To evaluate the efficacy and safety of NRCT-101SR compared to placebo in subjects 13-17 years of age with ADHD...

10 locations(Anaheim, Lakeland, Maitland)
160 participants
Neurocentria, Inc.
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RecruitingNCT06971614

A Study of T3011 in Patients With BCG-Unresponsive NMIBC or BCG-Exposed, Chemotherapy-Unresponsive NMIBC

This is a Phase II clinical study to evaluate the efficacy and safety of intravesical T3011 injection in participants with BCG-unresponsive high-risk NMIBC or BCG-exposed, chemotherapy-unresponsive in...

2 locations(Queen Creek, Tampa)
160 participants
ImmVira Pharma Co. Ltd
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RecruitingNCT06770582

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

This phase II trial compares the use of pembrolizumab and radiation therapy to chemotherapy with cisplatin, gemcitabine, 5-fluorouracil or mitomycin-C and radiation therapy for the treatment of non-mu...

10 locations(Bakersfield, Los Angeles, Los Angeles)
160 participants
National Cancer Institute (NCI)
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RecruitingNCT03375307

Testing Olaparib in Patients With Advanced or Metastatic (Cancer That Has Spread) Bladder Cancer and Other Genitourinary Tumors With DNA-Repair Genetic Changes

This phase II trial studies how well olaparib works in treating patients with bladder cancer and other genitourinary tumors with deoxyribonucleic acid (DNA)-repair defects that has spread to other pla...

10 locations(Encinitas, Irvine, La Jolla)
150 participants
National Cancer Institute (NCI)
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RecruitingNCT05589181

High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)

This project, involving two distinct clinical trials, tests whether induction to a higher than currently recommended buprenorphine (BUP) induction dose is safe and can improve the proportion of patien...

7 locations(Sylmar, Minneapolis, St Louis)
140 participants
Rutgers, The State University of New Jersey
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RecruitingNCT06055439

A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy

The goal of this clinical trial is to evaluate CHM-2101, an autologous CDH17 CAR T-cell therapy for the treatment of advanced gastrointestinal (GI) cancers that are relapsed or refractory to at least ...

4 locations(Atlanta, Chicago, Philadelphia)
135 participants
Chimeric Therapeutics
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RecruitingNCT05951179

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

TARA-002-101-Ph2 is an open-label study to investigate the safety and anti-tumor activity of intravesical instillation of TARA-002 in adults 18 years of age or older with high-grade CIS NMIBC (± Ta/T1...

10 locations(Phoenix, Los Angeles, Orange)
127 participants
Protara Therapeutics
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RecruitingNCT03945162

Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients

This is a phase II, open-label, single-arm, multi-center Study conducted in Canada and the United States. Patients with NMIBC CIS (with or without resected papillary disease (Ta, T1)) that are conside...

10 locations(Chicago, Bala, Myrtle Beach)
125 participants
Theralase® Technologies Inc.
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RecruitingNCT06496750

Ketamine for Methamphetamine Use Disorder

This study aims to determine whether treatment response with IV ketamine is superior to treatment response with IV midazolam in adults with moderate to severe MUD. The study design is a 12-week rando...

4 locations(Albuquerque, New York, Greenville)
120 participants
University of Texas Southwestern Medical Center
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RecruitingNCT07061964

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

This phase II trial tests the effect of giving pembrolizumab in combination with radiation therapy after chemotherapy in preventing surgery to remove the bladder in patients with muscle invasive bladd...

5 locations(Decatur, Decatur, Effingham)
111 participants
National Cancer Institute (NCI)
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RecruitingNCT04219280

Evaluating Treatment of ADHD in Children with Down Syndrome

Children with Down syndrome (DS) have a 3-5 time greater prevalence of Attention Deficit Hyperactivity Disorder (ADHD) than typically developing (TD) children. Despite this higher risk of ADHD, rates ...

4 locations(Sacramento, Boston, Cincinnati)
100 participants
Children's Hospital Medical Center, Cincinnati
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RecruitingNCT06483334

A Study of Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04)

This study is a substudy being conducted under one pembrolizumab umbrella master study KEYMAKER-U04. The substudy will consist of 2 parts. Part 1 will evaluate the safety and preliminary efficacy of s...

10 locations(San Francisco, Chicago, Indianapolis)
98 participants
Merck Sharp & Dohme LLC
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RecruitingNCT06331299

A Phase 3 Study of UGN-103 for Treatment of Patients With Low-grade Intermediate-risk Non-muscle Invasive Bladder Cancer

This Phase 3, single-arm, multicenter study will evaluate the efficacy and safety of UGN-103, a novel formulation of UGN-102, instilled in the urinary bladder of patients with low-grade non-muscle inv...

10 locations(San Diego, Powder Springs, Indianapolis)
92 participants
UroGen Pharma Ltd.
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RecruitingNCT06995677

Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

Phase 2 Study of TYRA-300 in FGFR3 Altered Low Grade, Intermediate Risk NMIBC...

3 locations(San Diego, Myrtle Beach, Nashville)
90 participants
Tyra Biosciences, Inc
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RecruitingNCT05491525

A Study of Vibegron in Pediatric Participants 2 Years to Less Than (<) 18 Years of Age With NDO and on CIC

The purpose of this study is to evaluate the safety, efficacy, and PK of vibegron in pediatric participants with NDO who are regularly using CIC...

6 locations(Orange, Jacksonville, Wichita)
85 participants
Urovant Sciences GmbH
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RecruitingNCT05710848

A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

This is a first-in-human (FIH), Phase 1/2a, multi center, open-label, single treatment, dose escalation and expansion study designed to determine the safety and tolerability of STM-416 in patients wit...

10 locations(Tucson, Gainesville, Boston)
75 participants
SURGE Therapeutics
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RecruitingNCT05932680

Limited-duration Teclistamab

This is a single-arm, non-inferiority study in which patients who have achieved a very good partial response (VGPR) or better, according to International Myeloma Working Group (IMWG) response criteria...

4 locations(Iowa City, New York, Philadelphia)
75 participants
Abramson Cancer Center at Penn Medicine
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RecruitingNCT05551793

Regeneron AA Multicenter (Dupilumab)

This is a prospective, randomized, double blind, placebo-controlled clinical trial. The study will take place at 4 sites. This trial will enroll a total of 68 patients with moderate to severe AA (affe...

3 locations(Irvine, New York, Rochester)
68 participants
Emma Guttman
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RecruitingNCT05312671

Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer

This is a single arm, Phase II trial involving the use of atezolizumab plus platinum and etoposide for patients with locally advanced urothelial cancer. The primary goal of this trial is to assess the...

2 locations(Washington D.C., Baltimore)
63 participants
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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RecruitingNCT06673368

A Phase 2 Randomized Double-Blind, Parallel, Adaptive-Design, Clinical Trial to Evaluate the Safety and Efficacy of NRCT-101SR With NRCT-202XR Compared to NRCT-202XR Alone in Subjects With Attention-Deficit/Hyperactivity Disorder

A combination therapy of NRCT-101 with NRCT-202 is being developed for patients with ADHD....

5 locations(Maitland, Decatur, Savannah)
60 participants
Neurocentria, Inc.
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RecruitingNCT05137262

A Phase II Multicenter Study of Chemotherapy Versus Chemotherapy Plus Durvalumab (MEDI 4736) in Patients With Lymph Node Positive Urothelial Carcinoma of the Bladder

This is a phase II randomized study of standard of care (SOC) neo-adjuvant cisplatin chemotherapy (NAC) versus NAC plus durvalumab in patients with either clinical or pathologic intra-pelvic node-posi...

2 locations(Bloomington, Houston)
60 participants
M.D. Anderson Cancer Center
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RecruitingNCT06503614

A Trial of Durvalumab (MEDI4736) Plus Monalizumab in Non-Muscle-Invasive Bladder Cancer

This is a phase 2 open-label two cohort study of durvalumab plus monalizumab in patients with BCG-unresponsive or BCG-exposed CIS NMIBC. Arm A will enroll 43 participants who have cancer in situ (CIS)...

2 locations(New Brunswick, New York)
60 participants
John Sfakianos
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RecruitingNCT04305743

Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A

Currently, in clinical practice there has been no standardization in the number of injections a single dose of intradetrusor onabotulinumtoxin A is administered in. Given the increasing use of this tr...

2 locations(Washington D.C., Tampa)
60 participants
University of South Florida
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RecruitingNCT03317158

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

Upon successful screening and registration, enrollment to durvalumab monotherapy (cohort 1) will begin. If DLT criteria outlined in the protocol are exceeded with durvalumab monotherapy (cohort 1), th...

10 locations(Phoenix, Stanford, Chicago)
55 participants
Noah Hahn, M.D.
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RecruitingNCT07043972

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

The goal of this clinical trial is to learn if a chemotherapy combination called gemcitabine and carboplatin (GC) works to treat advanced urothelial cancer in people who have already been treated with...

2 locations(Philadelphia, Philadelphia)
55 participants
Fox Chase Cancer Center
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RecruitingNCT06394830

Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS)

This is an open-label study that will enroll participants with Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS). The study will assess PRN (as needed) dosing of up to 6 intravesical (via cathet...

5 locations(Tucson, Fresno, Tustin)
50 participants
Vaneltix Pharma, Inc.
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RecruitingNCT02934568

Ribociclib (LEE011) Rollover Study for Continued Access

This study is to allow continued use of ribociclib (LEE011) as single agent or in combination with other investigational treatments in patients benefitting from treatment in an eligible Novartis-spons...

10 locations(Birmingham, Boston, Ann Arbor)
50 participants
Novartis Pharmaceuticals
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RecruitingNCT06493370

Intravenous Ascorbate Plus Gemcitabine/Carboplatin: A Novel and Cost-Effective Alternative With Evident Efficacy in Patients With Muscle Invasive Bladder Cancer

This is a phase II, single arm, Simon two-stage design, trial, enrolling patients with cisplatin ineligible MIBC and/or those patients who decline cisplatin based NAC. Assess rates of pathologic down...

2 locations(Iowa City, Kansas City)
48 participants
University of Kansas Medical Center
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RecruitingNCT06809140

Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

Patients with MIBC will receive 3 cycles (C1-C3) of induction enfortumab vedotin plus pembrolizumab followed by restaging including MRI of the bladder, urine cytology, and cystoscopy with TURBT of any...

3 locations(Indianapolis, New York, Philadelphia)
47 participants
Matthew Galsky
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RecruitingNCT04458545

Clinical Trials of Multivalent Opioid Vaccine Components

Currently, abuse of prescription opioid analgesics and heroin is a serious problem in the U.S. Although several medications, including methadone, buprenorphine, and naltrexone, are available and effec...

2 locations(Eatontown, New York)
45 participants
New York State Psychiatric Institute
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RecruitingNCT03520491

A Study to Test the Safety of Immunotherapy With Nivolumab Alone or With Ipilimumab Before Surgery for Bladder Cancer Patients Who Are Not Suitable for Chemotherapy

The purpose of this study is to test if immunotherapy with nivolumab alone or in combination with ipilimumab is safe and does not delay the planned bladder cancer surgery. The investigators want to se...

7 locations(Basking Ridge, Middletown, Montvale)
45 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNCT03504163

Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]

The purpose of this study is to find out the effectiveness of pembrolizumab in combination with BCG as a first line therapy for participants with high grade T1 bladder cancer who are at "high risk" fo...

7 locations(Basking Ridge, Middletown, Montvale)
45 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNCT03914794

A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

This phase II trial studies how well Pemigatinib (an orally administered inhibitor of fibroblast growth factor receptors 1, 2, and 3) works in non-muscle invasive bladder cancer (NMIBC) patients with ...

6 locations(Washington D.C., Baltimore, Syracuse)
43 participants
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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RecruitingNCT04789044

Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)

The overall objective of this study is to determine the safety of PEG fusion when used with primary repair or reconstruction in patients with an acute upper extremity peripheral nerve injury. PEG is s...

7 locations(Baltimore, Baltimore, Bethesda)
40 participants
Major Extremity Trauma Research Consortium
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RecruitingNCT06637423

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)

The goal of the study is to learn about the safety of Sacituzumab Tirumotecan and if people can tolerate it when given in the bladder and find the highest dose that people can take without having cert...

10 locations(Bakersfield, Tampa, Chicago)
32 participants
Merck Sharp & Dohme LLC
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RecruitingNCT04701918

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

This research study is examining the effectiveness of pembrolizumab plus cryoablation or aveluma plus cryoablation on people with urothelial carcinoma, including bladder cancer, that has spread....

2 locations(Boston, Boston)
30 participants
Massachusetts General Hospital
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RecruitingNCT05756569

Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology

This phase II trial tests how well enfortumab vedotin (EV) and pembrolizumab works in treating patients with bladder cancer of variant histology (a group of less common types of bladder cancer) that h...

4 locations(Atlanta, Atlanta, Atlanta)
25 participants
Emory University
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RecruitingNCT06263153

Futibatinib in Combination With Durvalumab Prior to Cystectomy for the Treatment of Muscle-Invasive Bladder Cancer Patients Who Are Ineligible for Cisplatin-based Therapy

This phase II trial tests how well the combination of futibatinib and durvalumab given before cystectomy works in treating patients with muscle-invasive bladder cancer (MIBC) who are ineligible for ci...

3 locations(Ann Arbor, Cleveland, Columbus)
24 participants
Yuanquan Yang
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RecruitingNCT05239624

Enfortumab Vedotin and Pembrolizumab in People with Bladder Cancer

This study will test whether enfortumab vedotin combined with pembrolizumab is an effective treatment for people with bladder cancer (urothelial carcinoma) involving the lymph nodes who are going to h...

10 locations(Miami, Basking Ridge, Middletown)
23 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNCT06596291

Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization

This is a first-in-human, Phase 1b/2a, open-label, dose-escalation study of a single treatment course consisting of multiple intradetrusor injections of EG110A in male and female adult participants wi...

4 locations(Downey, Ann Arbor, Philadelphia)
16 participants
EG 427
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Top Cities for ADHD Clinical Trials

ADHD clinical trials are recruiting across 185 cities. Here are the cities with the most active studies:

About ADHD

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity that interferes with functioning. It affects both children and adults. Treatment includes behavioral therapy, stimulant and non-stimulant medications, and educational support.

Clinical trials are advancing new treatments for adhd. Currently, 73 studies are recruiting a combined 15,786 participants across the United States. Research is being conducted by 53 organizations including BicycleTx Limited, ECOG-ACRIN Cancer Research Group, Eli Lilly and Company and 50 others.

2026 ADHD Research Landscape

As of March 2026, the adhd clinical trial landscape includes 73 actively recruiting studies across 185 cities in the United States. These studies are collectively seeking 15,786 participants, with an average enrollment target of 216 per study.

Research is being led by 53 different organizations, including BicycleTx Limited, ECOG-ACRIN Cancer Research Group, Eli Lilly and Company, ImmunityBio, Inc., Janssen Research & Development, LLC, and 48 others. The large number of sponsors reflects significant research interest and investment in adhd treatment advancement.

Geographically, adhd trials are most concentrated in New York, New York (23 trials); Los Angeles, California (19 trials); Boston, Massachusetts (13 trials); Chicago, Illinois (12 trials); Little Rock, Arkansas (10 trials) and 7 other cities.

Featured ADHD Studies

Highlighted recruiting studies for adhd, selected by enrollment size and research scope.

RecruitingNCT06225596

Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

This is a global, multicenter, randomized, open-label study, with an adaptive design. The main objective of the study is to measure the efficacy and safety of BT8009 (zelenectide pevedotin) as monotherapy and in combination with pembrolizumab in participants with locally advanced or metastatic urothelial cancer (UC). The study includes a dose selection phase followed by an adaptive design continua...

Sponsor: BicycleTx Limited· 956 participants· 10 locations (Little Rock, Fullerton, Orange, San Francisco)
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RecruitingNCT05538663

Intravesical BCG vs GEMDOCE in NMIBC

The study hypothesis is that BCG naïve non-muscle invasive bladder cancer (NMIBC) patients treated with intravesical Gemcitabine + Docetaxel (GEMDOCE) will result in a non-inferior event-free survival (EFS) compared to standard treatment with intravesical BCG. The purpose of this study is to test whether Gemcitabine + Docetaxel is a better or worse treatment than the usual BCG therapy approach. Th...

Sponsor: ECOG-ACRIN Cancer Research Group· 870 participants· 10 locations (Birmingham, Fairbanks, Gilbert, Goodyear)
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RecruitingNCT06876649

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

The master protocol study J2N-MC-JZNY provides a framework to enable the evaluation of the long-term safety and efficacy of pirtobrutinib after completion of clinical studies evaluating pirtobrutinib. The clinical studies that will feed into this master protocol are referred to as originator studies. The master protocol will govern individual study-specific appendices (ISAs) that will represent pa...

Sponsor: Eli Lilly and Company· 787 participants· 10 locations (Miami, Sarasota, Atlanta, Chicago)
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Frequently Asked Questions About ADHD Clinical Trials

Are there adhd clinical trials near me?

Yes, there are 73 adhd clinical trials currently recruiting across 185+ cities in the United States, including New York, New York; Los Angeles, California; Boston, Massachusetts. Browse the studies above to find one at a location convenient for you.

How do I join a adhd clinical trial?

To join a adhd clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.

Are adhd clinical trials free?

Yes, participation in adhd clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.

What types of adhd treatments are being studied?

Current adhd clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 53 research organizations.

Is it safe to participate in adhd clinical trials?

Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.

Data updated March 2, 2026 from ClinicalTrials.gov

About This Data

Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.

Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.

Page reviewed by the HelloStudys Research Team · Last updated March 2, 2026 · Data from ClinicalTrials.gov