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NCT05049057RECRUITINGIRB Ready

Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI

Sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine

Quick Self-Assessment

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1 of 404 participants interested
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Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

This study aims to assess the effect and safety of erenumab compared to placebo for the treatment of acute posttraumatic headache (PTH) in military service members and civilians with mild traumatic brain injury (mTBI).

Who Can Participate

Inclusion Criteria

Male or female โ‰ฅ18 and โ‰ค50 years of age
mTBI from any cause including impact, rotational acceleration, blast, or a combination, has occurred within the prior 7 days
PTH has occurred within the prior 7 days
Able to provide informed consent
Likely to stay in the same geographical area for the duration of study
Has a personal health care provider for standard of care PTH and TBI, including education, diagnostic procedures including neuroimaging and treatment, as deemed clinically indicated by the health care provider

Exclusion Criteria

Sustained a moderate or severe TBI, rather than mTBI, indicated with at least 1 of the following associated with head injury: 1. abnormal structural imaging 2. loss of consciousness for \>30 minutes 3. alteration of consciousness/mental state for \>24 hours 3. post-traumatic amnesia for \>1 day
Participants with ongoing chronic migraine or other chronic daily headache disorders at the time of injury

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

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Study Type

INTERVENTIONAL

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Target Enrollment

404 participants

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Age Range

18 Years - 50 Years

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Gender

ALL

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Sponsor

Henry M. Jackson Foundation for the Advancement of Military Medicine

Study Locations

Choose your preferred location or select flexible during enrollment

RECRUITING

Fort Bragg

North Carolina

Location available
View Fort Bragg location page
NOT_YET_RECRUITING

Pittsburgh

Pennsylvania

Location available
View Pittsburgh location page
RECRUITING

El Paso

Texas

Location available
View El Paso location page
NOT_YET_RECRUITING

Tacoma

Washington

Location available
View Tacoma location page

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

Ready to Make a Difference?

Express your interest in this groundbreaking clinical trial

๐Ÿ”’ Secure ยท ๐Ÿฅ Expert Care

Looking for Post-Traumatic Headache Treatment in Fort Bragg?

Join others in North Carolina exploring innovative treatment options through clinical research

Post-Traumatic Headache Treatment Options in Fort Bragg, North Carolina

If you're searching for Post-Traumatic Headache treatment in Fort Bragg, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Fort Bragg, Pittsburgh, El Paso and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Post-Traumatic Headache. All study-related care is provided at no cost to participants.

Local Sites
3 locations in North Carolina
Now Enrolling
Up to 404 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Post-Traumatic Headache?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Post-Traumatic Headache

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Post-Traumatic Headache Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT05049057. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.