Charlottesville, VANCT05141682Now EnrollingIRB Ready

T-cell Lymphocytic Leukemia Clinical Trial in Charlottesville, VA

Access cutting-edge t-cell lymphocytic leukemia treatment through this clinical trial at a research site in Charlottesville. Study-provided care at no cost to qualified participants.

Sponsored by Jonathan Brammer

Quick Self-Assessment

See if you qualify for this Charlottesville location

Preparing your pre-screening questions...

Expert Care in Charlottesville

Access t-cell lymphocytic leukemia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related t-cell lymphocytic leukemia treatment provided free

Apply for This Charlottesville Location

Check if you qualify for this t-cell lymphocytic leukemia clinical trial in Charlottesville, VA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Charlottesville

    Convenient for VA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charlottesville site if eligible
  4. 4Begin participation

About This T-cell Lymphocytic Leukemia Study in Charlottesville

This phase I/II trial studies the best dose, possible benefits and/or side effects of oral azacitidine in treating patients with T-cell large granular lymphocytic leukemia that has come back (relapsed) or has not responded to previous treatment (refractory). Chemotherapy drugs, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Sponsor: Jonathan Brammer

Who Can Participate

Inclusion Criteria

Age 18 or older
Diagnosis of T-LGLL defined as: CD3+CD8+ cell population \> 650/mm\^3 and the presence of a clonal T-cell receptor (within 1 month of diagnosis). This also includes patients with rare T-LGLL variants include CD4+ T-LGLL, and gamma/delta T-LGLL which can be CD4- and CD8, though patients still must have an LGL cell population \>500 cells/mm3 and the presence of a clonal T-cell receptor within 1 month of diagnosis or relapse. Note: patients with myelodysplastic syndrome (MDS)-like T-LGLL may be included with principal investigator (PI) approval even if CD3+CD8+ cell population is \< 650/mm\^3, though +TCR is required. Natural-killer (NK) large granular lymphocytic leukemia (LGL) is also permitted, provided there is a clonal NK-cell population noted with \> 500 cells/mm\^3
Failed at least one line of frontline therapy; off treatment for at least 14 days or 5 half-lives, whichever is longer
Require Treatment for T-LGLL (One or more required) *

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charlottesville?

Yes, this clinical trial (NCT05141682) has an active research site in Charlottesville, VA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

T-cell Lymphocytic Leukemia Treatment Options in Charlottesville, VA

If you're searching for t-cell lymphocytic leukemia treatment options in Charlottesville, VA, this clinical trial (NCT05141682) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charlottesville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced t-cell lymphocytic leukemia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all t-cell lymphocytic leukemia clinical trials near you to find additional studies recruiting in your area.

More Leukemia Trials in Charlottesville, VA

See all leukemia clinical trials recruiting in Charlottesville — not just this study.

Browse Leukemia Trials in Charlottesville

Ready to Join in Charlottesville?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Charlottesville, VA