Orange, CANCT05267821Now EnrollingIRB Ready

Pediatric Sepsis Clinical Trial in Orange, CA

Access cutting-edge pediatric sepsis treatment through this clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by Nationwide Children's Hospital

Quick Self-Assessment

See if you qualify for this Orange location

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Expert Care in Orange

Access pediatric sepsis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related pediatric sepsis treatment provided free

Apply for This Orange Location

Check if you qualify for this pediatric sepsis clinical trial in Orange, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Pediatric Sepsis Study in Orange

The TRIPS study is a prospective, multi-center, double-blind, adaptively randomized, placebo-controlled clinical trial of the drug anakinra for reversal of moderate to severe hyperinflammation in children with sepsis-induced multiple organ dysfunction syndrome (MODS).

Sponsor: Nationwide Children's Hospital

Who Can Participate

Inclusion Criteria

≥ 40 weeks corrected gestational age to \< 18 years; AND
Admission to the PICU or CICU; AND
Onset of ≥ 2 new organ dysfunctions within the last 3 calendar days (compared to pre-sepsis baseline) as measured by the modified Proulx criteria; AND
Documented or suspected infection as the MODS inciting event.

Exclusion Criteria

Weight \<3kg; OR
Limitation of care order at the time of screening; OR
Patients at high likelihood of progression to brain death in opinion of the clinical team; OR
Moribund condition in which the patient is unlikely to survive the next 48 hours in opinion of the clinical team; OR
Current or prior diagnosis of hemophagocytic lymphohistiocytosis or macrophage activation syndrome; OR
Peripheral white blood cell count \< 1,000 cells/mm3 as the result of myeloablative therapy OR receipt of myeloablative therapy within the previous 14 days; OR
Known allergy to anakinra, or E. coli-derived products; OR
Known pregnancy; OR

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT05267821) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Pediatric Sepsis Treatment Options in Orange, CA

If you're searching for pediatric sepsis treatment options in Orange, CA, this clinical trial (NCT05267821) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this clinical trial. You'll receive care from experienced pediatric sepsis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all pediatric sepsis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Orange, CA