Orange, CANCT05566795Now EnrollingIRB Ready

Low-Grade Glioma Clinical Trial in Orange, CA

Access cutting-edge low-grade glioma treatment through this clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by Day One Biopharmaceuticals, Inc.

Quick Self-Assessment

See if you qualify for this Orange location

Preparing your pre-screening questions...

Expert Care in Orange

Access low-grade glioma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related low-grade glioma treatment provided free

Apply for This Orange Location

Check if you qualify for this low-grade glioma clinical trial in Orange, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Low-Grade Glioma Study in Orange

This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monotherapy versus standard of care (SoC) chemotherapy in participants with pediatric low-grade glioma (LGG) harboring an activating rapidly accelerated fibrosarcoma (RAF) alteration requiring first-line systemic therapy.

Sponsor: Day One Biopharmaceuticals, Inc.

Who Can Participate

Inclusion Criteria

Less than 25 years of age with LGG with known activating RAF alteration.
Histopathologic diagnosis of glioma or glioneuronal tumor.
At least one measurable lesion as defined by RANO criteria.
Meet indication for first-line systemic therapy.

Exclusion Criteria

Participant has any of the following tumor-histological findings: 1. Schwannoma 2. Subependymal giant cell astrocytoma (Tuberous Sclerosis) 3. Diffuse intrinsic pontine glioma, even if histologically diagnosed as World Health Organization (WHO) Grade I-II
Participant's tumor has additional pathogenic molecular alterations, including but not limited to a) isocitrate dehydrogenase (IDH) 1/2 mutation, b) Histone H3 mutation, and c) neurofibromatosis Type 1 (NF-1) loss of function alteration.
Known or suspected diagnosis of NF-1/ neurofibromatosis Type 2 (NF-2).
Prior or ongoing nonsurgical anticancer therapy for this indication (eg, chemotherapy, oral/IV targeted therapy) including radia

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT05566795) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Low-Grade Glioma Treatment Options in Orange, CA

If you're searching for low-grade glioma treatment options in Orange, CA, this clinical trial (NCT05566795) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this clinical trial. You'll receive care from experienced low-grade glioma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all low-grade glioma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Orange, CA