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NCT05813288RECRUITINGIRB Ready

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3)

(EXHALE-3)

Sponsored by Areteia Therapeutics

Quick Self-Assessment

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1 of 930 participants interested
0% interest

Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

The objective of this clinical study is to investigate the safety, tolerability, and efficacy of dexpramipexole in participants with inadequately controlled severe eosinophilic asthma.

Who Can Participate

Inclusion Criteria

Signed informed consent form and assent form, as appropriate. 2. Male or female โ‰ฅ12 years of age at Screening Visit 1. Asthma-related criteria 3. Documented physician diagnosis of asthma for โ‰ฅ12 months prior to Screening Visit 1. 4. Eosinophil count of โ‰ฅ0.30x10โน/L at Screening Visit 1. If the initial value is between 0.250x10โน/L to 0.299x10โน/L, then this may be repeated once at an unscheduled visit (prior to Screening Visit 2). 5. Treatment of asthma, participants must satisfy all the below (items a to c): 1. Participants who have received asthma controller medication with medium or high dose inhaled corticosteroids (ICS โ‰ฅ500 ฮผg/day fluticasone propionate dry powder formulation daily or clinically comparable, per GINA 2021) on a regular basis for at least 12 months prior to Screening Visit 1. 2. Documented treatment with a stable dose of either medium or high dose ICS for at least 3 months prior to Visit 1. The ICS may be contained within an ICS/long-

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

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Study Type

INTERVENTIONAL

๐Ÿ‘ฅ

Target Enrollment

930 participants

๐ŸŽ‚

Age Range

12 Years - 99 Years

โšง

Gender

ALL

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Sponsor

Areteia Therapeutics

Study Locations

Choose your preferred location or select flexible during enrollment

Unknown

Mobile

Alabama

Location available
View Mobile location page
Unknown

Chandler

Arizona

Location available
View Chandler location page
Unknown

Peoria

Arizona

Location available
View Peoria location page
Unknown

Surprise

Arizona

Location available
View Surprise location page
Unknown

Tucson

Arizona

Location available
View Tucson location page
Unknown

Little Rock

Arkansas

Location available
View Little Rock location page
Unknown

Canoga Park

California

Location available
View Canoga Park location page
Unknown

Inglewood

California

Location available
View Inglewood location page
Unknown

Laguna Niguel

California

Location available
View Laguna Niguel location page

๐Ÿ“ And 67 more locations available

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

Ready to Make a Difference?

Express your interest in this groundbreaking clinical trial

๐Ÿ”’ Secure ยท ๐Ÿฅ Expert Care

Looking for Severe Asthma Treatment in Mobile?

Join others in Alabama exploring innovative treatment options through clinical research

Severe Asthma Treatment Options in Mobile, Alabama

If you're searching for Severe Asthma treatment in Mobile, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Mobile, Chandler, Peoria and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Severe Asthma. All study-related care is provided at no cost to participants.

Local Sites
3 locations in Alabama
Now Enrolling
Up to 930 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Severe Asthma?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Severe Asthma

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Severe Asthma Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT05813288. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.