Los Angeles, CANCT05987332Now EnrollingIRB Ready

Uveal Melanoma Clinical Trial in Los Angeles, CA

Access cutting-edge uveal melanoma treatment through this clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by IDEAYA Biosciences

Quick Self-Assessment

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Expert Care in Los Angeles

Access uveal melanoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related uveal melanoma treatment provided free

Apply for This Los Angeles Location

Check if you qualify for this uveal melanoma clinical trial in Los Angeles, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This Uveal Melanoma Study in Los Angeles

This is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotinib or investigator's choice of treatment (pembrolizumab, ipilimumab + nivolumab, or dacarbazine).

Sponsor: IDEAYA Biosciences

Who Can Participate

Inclusion Criteria

Histological or cytological confirmed Metastatic Uveal Melanoma
HLA-A\*02:01 negative
No prior systemic therapy in the metastatic or advanced setting or regional or liver-directed therapy. Ablations or surgical resection of oligometastatic disease, and neoadjuvant or adjuvant therapy is allowed
Measurable disease per RECIST 1.1
Able to be safely administered and absorb study therapy
ECOG performance status 0 or 1
Life expectancy of ≥3 months
Adequate organ function

Exclusion Criteria

Previous treatment with a PKC inhibitor (including prior treatment with IDE196), an inhibitor directly targeting MET, or an inhibitor directly targeting GNAQ/11
Concurrent malignant disease
AEs from prior anti-cancer therapy that have not resolved to Grade ≤1
Symptomatic or untreated central nervous system (CNS) metastases, or CNS metastases that require corticosteroids
High risk of syncope
Known AIDS related illness or active Hep B/C
Active adrenal ins

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT05987332) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Uveal Melanoma Treatment Options in Los Angeles, CA

If you're searching for uveal melanoma treatment options in Los Angeles, CA, this clinical trial (NCT05987332) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this clinical trial. You'll receive care from experienced uveal melanoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all uveal melanoma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Los Angeles, CA