Orange, CANCT06393712Now EnrollingIRB Ready

Cerebral Amyloid Angiopathy Clinical Trial in Orange, CA

Access cutting-edge cerebral amyloid angiopathy treatment through this clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by Alnylam Pharmaceuticals

Quick Self-Assessment

See if you qualify for this Orange location

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Expert Care in Orange

Access cerebral amyloid angiopathy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related cerebral amyloid angiopathy treatment provided free

Apply for This Orange Location

Check if you qualify for this cerebral amyloid angiopathy clinical trial in Orange, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Cerebral Amyloid Angiopathy Study in Orange

The purpose of the study is to evaluate the effect of ALN-APP on measures of CAA disease progression and to characterize the safety, tolerability, and pharmacodynamics (PD) of ALN-APP in adult patients with sporadic CAA (sCAA) and Dutch-type CAA (D-CAA). The study will be conducted over 2 periods: a 24-month double-blind treatment period and an optional 18-month open-label extension (OLE) period. The estimated duration of study participation, inclusive of screening, treatment, and additional saf

Sponsor: Alnylam Pharmaceuticals

Who Can Participate

Inclusion Criteria

(sporadic CAA patients):
Is 50 years or older
Has probable CAA per the Boston Criteria Version 2.0 Inclusion Criteria (Dutch-type CAA patients):
Is 30 years or older
Has known E693Q amyloid precursor protein (APP) gene mutation for Dutch-type CAA

Exclusion Criteria

Moderate or severe stage Alzheimer's disease (AD) or significant cognitive impairment (CI)
Has a history of previous clinical intracerebral hemorrhage (ICH) with onset less than 90 days prior to anticipated randomization in the study
Has alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \>3×upper limit of normal (ULN) at Screening
Has estimated glomerular filtration rate (eGFR) \<30 mL/min/1.73m\^2 at Screening
Has recently received an investigational agent
Has had treatment with amyloid-targeting antibody Note: other protocol defined inclusion / exclusion criteria apply

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT06393712) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Cerebral Amyloid Angiopathy Treatment Options in Orange, CA

If you're searching for cerebral amyloid angiopathy treatment options in Orange, CA, this clinical trial (NCT06393712) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this clinical trial. You'll receive care from experienced cerebral amyloid angiopathy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all cerebral amyloid angiopathy clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Orange, CA