Boston, MANCT06709495Now EnrollingIRB Ready

Sarcoma Clinical Trial in Boston, MA

Access cutting-edge sarcoma treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by David S Shulman, MD

Quick Self-Assessment

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Expert Care in Boston

Access sarcoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related sarcoma treatment provided free

Apply for This Boston Location

Check if you qualify for this sarcoma clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Sarcoma Study in Boston

This research is being done to test a new drug called PEEL-224 in combination with two commercially available drugs, Vincristine and Temozolomide, and to determine how effective this combination of drugs is at treating Ewing Sarcoma (EWS) and Desmoplastic Small Round Cell Tumor (DSRCT), as well as multiple other kinds of sarcomas. The names of the study drugs and biological agents involved in this study are: * PEEL-224 (a type of Topoisomerase 1 inhibitor) * Vincristine (A type of vinca alkalo

Sponsor: David S Shulman, MD

Who Can Participate

Inclusion Criteria

-Patients in all cohorts must have relapsed or refractory disease after standard therapy. Inclusion Criteria Phase 1 (only) diagnosis requirements: -Patients must have:
Evaluable or measurable disease; and
Histologic diagnosis of sarcoma Inclusion Criteria Phase 2 (only) diagnosis requirements
EWS cohort: Patients must have:
RECIST measurable disease at study entry;
Histologic diagnosis consistent with Ewing sarcoma; and
Molecular evidence of a FET-ETS family translocation including but not limited to any of the following:
EWSR1::FLI1, EWSR1::ERG, EWSR1::ETV1, EWSR1::ETV4, EWSR1::FEV, FUS::FLI1, FUS::ERG
DSRCT cohort: Patients must have:
RECIST measurable disease at study entry;
Histologic diagnosis consistent with DSRCT; and
Molecular evidence of an EWSR1::WT1 fusion
Other sarcoma cohort: Patients must have:
RECIST evaluable or measurable disease; and
Histologic diagnosis of sarcoma. Patients with EWS or DSR

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT06709495) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Sarcoma Treatment Options in Boston, MA

If you're searching for sarcoma treatment options in Boston, MA, this clinical trial (NCT06709495) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced sarcoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all sarcoma clinical trials near you to find additional studies recruiting in your area.

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