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NCT07038200RECRUITINGIRB Ready

A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

(FORTITUDE-3)

Sponsored by Avidity Biosciences, Inc.

Quick Self-Assessment

See if you qualify and express your interest

Preparing your pre-screening questions...
๐Ÿ“Š
1 of 200 participants interested
1% interest

Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

A Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous AOC 1020 for the Treatment of Facioscapulohumeral Muscular Dystrophy (FSHD)

Who Can Participate

Inclusion Criteria

Clinical and genetic diagnosis of FSHD1 or FSHD2
Ability to walk independently at pre-specified walking speed (orthoses and ankle braces allowed) for at least 10 meters at screening
Adequate muscle strength based on QMT composite score

Exclusion Criteria

Breastfeeding, pregnancy, or intent to become pregnant during the study
Unwilling or unable to comply with contraceptive requirements
Abnormal lab values, conditions or diseases that would make the participant unsuitable for the study
Blood Pressure \> 140/90 mmHg at Screening
Treatment with another investigational drug or biological agent within 1 month of Screening or 5 half-lives of the drug, whichever is longer
Treatment with an oligonucleotide within 9 months of Screening

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

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Study Type

INTERVENTIONAL

๐Ÿ‘ฅ

Target Enrollment

200 participants

๐ŸŽ‚

Age Range

16 Years - 70 Years

โšง

Gender

ALL

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Sponsor

Avidity Biosciences, Inc.

Study Locations

Choose your preferred location or select flexible during enrollment

RECRUITING

Orange

California

Location available
View Orange location page
RECRUITING

Palo Alto

California

Location available
View Palo Alto location page
RECRUITING

Denver

Colorado

Location available
View Denver location page
RECRUITING

Gainesville

Florida

Location available
View Gainesville location page
RECRUITING

Iowa City

Iowa

Location available
View Iowa City location page
RECRUITING

Kansas City

Kansas

Location available
View Kansas City location page
RECRUITING

Baltimore

Maryland

Location available
View Baltimore location page
RECRUITING

Worcester

Massachusetts

Location available
View Worcester location page
RECRUITING

Rochester

New York

Location available
View Rochester location page

๐Ÿ“ And 5 more locations available

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

Ready to Make a Difference?

Express your interest in this groundbreaking clinical trial

๐Ÿ”’ Secure ยท ๐Ÿฅ Expert Care

Looking for Facioscapulohumeral Muscular Dystrophy Treatment in Orange?

Join others in California exploring innovative treatment options through clinical research

Facioscapulohumeral Muscular Dystrophy Treatment Options in Orange, California

If you're searching for Facioscapulohumeral Muscular Dystrophy treatment in Orange, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Orange, Palo Alto, Denver and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Facioscapulohumeral Muscular Dystrophy. All study-related care is provided at no cost to participants.

Local Sites
3 locations in California
Now Enrolling
Up to 200 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Facioscapulohumeral Muscular Dystrophy?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Facioscapulohumeral Muscular Dystrophy

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Facioscapulohumeral Muscular Dystrophy Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT07038200. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.