St Louis, MONCT07473102Now EnrollingIRB Ready

Abdominal Aortic Aneurysm Clinical Trial in St Louis, MO

Access cutting-edge abdominal aortic aneurysm treatment through this clinical trial at a research site in St Louis. Study-provided care at no cost to qualified participants.

Sponsored by Washington University School of Medicine

Quick Self-Assessment

See if you qualify for this St Louis location

Preparing your pre-screening questions…

Expert Care in St Louis

Access abdominal aortic aneurysm specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related abdominal aortic aneurysm treatment provided free

Apply for This St Louis Location

Check if you qualify for this abdominal aortic aneurysm clinical trial in St Louis, MO

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to St Louis

    Convenient for MO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit St Louis site if eligible
  4. 4Begin participation

About This Abdominal Aortic Aneurysm Study in St Louis

A first-in-human evaluation of \[64Cu\]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoing surgery (WU and Yale), evaluate radiotracer pharmacodynamics and correlate PET imaging characteristics (WU) with ex vivo tissue measurements (Yale).

Sponsor: Washington University School of Medicine

Who Can Participate

Inclusion Criteria

Healthy Volunteers
No history of claustrophobia or other preventing condition that has previously or would interfere with completion of protocol-specified imaging sessions.
Able to comprehend and willing to follow instructions for the study procedures as called for by the protocol.
Capable of lying still and supine within the PET/CT scanner for \~1 hour and follow instructions for breathing protocol during the CT portion.
No illicit drug use or other inhaled drug use (including pharmacologic agents, recreational agents, or illicit drugs) within the past year.
No known history of cardiac, pulmonary, hepatic or renal disease or diabetes

Exclusion Criteria

Healthy Volunteers
Inability to receive and sign informed consent;
Pregnant (confirmed by urine pregnancy test) and/or breastfeeding
Patient with chronic renal disease whose glomerular filtration rate (GFR) is less than 30 mL/min/1.73 m2
Patients with an unstable clinical condition that in the opinion of the principal investigators or designee precludes participation in the study.
Is deemed likely to be unable to perform all research procedures for any reason, (e.g., subjects unable to lie still or inability to tolerate up to 60 minutes in a supine position with arms up during the PET imaging procedures due to chronic back/shoulder pain or arthritis as assessed by physical examination and medical history).
Currently using recreational drugs.
Body weight of \>300 lbs. (weight limit of the PET table).
Currently enrolled in another study using an investigational drug or underwent a study the last year involving investigational use of radiotracers or CT would confound results or with a radiation exposure when combined with this study would be deemed as excessive by the Sponsor-Investigator. Inclusion Criteria: Patients with AAA electively or semi-electively scheduled for surgical repair
Men or women 40-80 years of age
Willing and able to provide informed consent
Medically managed hypertension and hyperlipidemia
No history of claustrophobia or other preventing condition that has previously or would interfere with completion of protocol-specified imaging sessions
Able to comprehend and willing to follow instructions for the study procedures as called for by the protocol
Patients with AAA indicated for surgical repair (5.0 \[female\] - 5.5cm \[male\]), incidentally identified large(r) AAAs (\>5.5 or 6.0 cm), and rapidly expanding AAAs (\> 0.5 cm in 6 months or \> 1 cm in 12 months) per Guidelines of the Society for Vascular Surgery. Exclusion Criteria: Patients with AAA electively or semi-electively scheduled for surgical repair
Inability to receive and sign informed consent.
Currently enrolled in another study using an investigational drug
Pregnant (confirmed by urine pregnancy test) and/or breastfeeding
Patient with chronic renal disease whose GFR is less than 30 mL/min/1.73 m2
Documented allergy to iodinated contrast and/or shellfish
Patients with an unstable clinical condition that in the opinion of the principal investigators or designee precludes participation in the study.
Inability to tolerate 60 minutes in a supine position with arms down at sides, as necessary for PET/CT.
Other conditions such as symptomatic/recently treated coronary disease, cancer requiring oncologic management, or autoimmune/inflammatory diseases (e.g., rheumatoid arthritis or multiple sclerosis).
Non-AAA volunteers may not carry a diagnosis of aortoiliac occlusive disease, as documented by their treating vascular surgeon, as significantly progressed atherosclerotic disease may demonstrate exaggerated, associated MMP activity.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in St Louis?

Yes, this clinical trial (NCT07473102) has an active research site in St Louis, MO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Abdominal Aortic Aneurysm Treatment Options in St Louis, MO

If you're searching for abdominal aortic aneurysm treatment options in St Louis, MO, this clinical trial (NCT07473102) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our St Louis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced abdominal aortic aneurysm specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all abdominal aortic aneurysm clinical trials near you to find additional studies recruiting in your area.

More Heart Attack Trials in St Louis, MO

See all heart attack clinical trials recruiting in St Louis — not just this study.

Browse Heart Attack Trials in St Louis →

Browse More Trials by Condition

Heart Attack TrialsAortic Aneurysm TrialsInterstitial Cystitis TrialsMyocardial Infarction TrialsAll Conditions →

Ready to Join in St Louis?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · St Louis, MO