25 Heart Attack Clinical Trials in St Louis, MO (2026)

Q: Are there heart attack clinical trials in St Louis?

Yes, there are 25 heart attack clinical trials currently recruiting in St Louis, MO.

Q: How do I join a clinical trial in St Louis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you.

Q: Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Heart Attack Studies in St Louis

NCT01522183Recruiting

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Post-marketing safety data on patients treated and untreated with eculizumab or ravulizumab....

St Louis, MO3,000 participantsAlexion Pharmaceuticals, Inc.

View Study Details

NCT05071144Recruiting

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

Creation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation, as well as patient-specific rods in pediatric spine de...

St Louis, MO700 participantsBoston Children's Hospital

View Study Details

NCT07115940Recruiting

Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well

SELECT LATE trial aims to evaluate if addition of endovascular thrombectomy to medical management in patients presenting with acute ischemic stroke and a proximal large vessel occlusion in the anterio...

St Louis, MONA408 participantsAmrou Sarraj

View Study Details

NCT05484115Recruiting

Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck

The HERCULES trial is a Randomized controlled clinical trial designed to prospectively compare endosuture aneurysm repair (ESAR) to standard endovascular aneurysm repair (EVAR) clinical outcomes in tr...

St Louis, MONA300 participantsRijnstate Hospital

View Study Details

NCT05462704Recruiting

Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy

Double blind, placebo controlled, multicenter randomized trial in pregnant women in the U.S. (N=300) to test the central hypothesis that IV iron in pregnant women with IDA (Hb\<11 g/dL and ferritin\<3...

St Louis, MOPHASE3300 participantsWomen and Infants Hospital of Rhode Island

View Study Details

NCT06880770Recruiting

Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

This study will evaluate the efficacy and safety of plozasiran in approximately 140 adult participants with severe hypertriglyceridemia (SHTG) and history of at least two prior acute pancreatitis (AP)...

St Louis, MOPHASE3288 participantsArrowhead Pharmaceuticals

View Study Details

NCT05654012Recruiting

Migraine in Adolescents

Aim 1. To identify psychophysical and neural factors predicting migraine onset in adolescents Aim 2a. To determine hormonal, psychophysical, and neural changes associated with migraine onset. Aim 2b...

St Louis, MONA250 participantsWashington University School of Medicine

View Study Details

NCT06226805Recruiting

Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

The purpose of this study is to evaluate the safety and tolerability of ascending doses (Part A) and selected doses (Part B) of BB-031 in acute ischemic stroke patients presenting within 24 hours of s...

St Louis, MOPHASE2228 participantsBasking Biosciences, Inc.

View Study Details

NCT06897930Recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

This is a Phase 1b/2, single-arm, open-label, multi-center, clinical study of AZD0120, a CD19/BCMA dual CAR T cell therapy, to evaluate the safety, tolerability, and efficacy in adult participants wit...

St Louis, MOPHASE1150 participantsAstraZeneca

View Study Details

NCT03813407Recruiting

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

Sodium zirconium cyclosilicate has been shown to be effective and safe in adults for the treatment of hyperkalaemia, and therefore it is expected to be beneficial in children. This study will evaluate...

St Louis, MOPHASE3140 participantsAstraZeneca

View Study Details

NCT05362773Recruiting

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

CP-MGD024-01 is a Phase 1, open-label, multi-center study of MGD024 as a single agent in participants with select blood cancers that have not responded to treatment with standard therapies or who have...

St Louis, MOPHASE1130 participantsMacroGenics

View Study Details

NCT06514794Recruiting

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

The T-RRex study evaluates the efficacy of WU-CART-007 for patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL) and to WU-CART-007 as a ther...

St Louis, MOPHASE2125 participantsWugen, Inc.

View Study Details

NCT06456463Recruiting

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

This study will be divided into 2 parts (Part 1 and Part 2). Part 1 will evaluate 2 doses of tagraxofusp (9 and 12 micrograms/kilogram/day \[μg/kg/day\]), used in combination with venetoclax and azaci...

St Louis, MOPHASE283 participantsStemline Therapeutics, Inc.

View Study Details

NCT06925542Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

This is a single-arm, open-label, multicenter, ascending dose Phase 1 study evaluating the safety and preliminary efficacy of CTX112 in adult subjects with refractory autoimmune diseases, including ac...

St Louis, MOPHASE180 participantsCRISPR Therapeutics

View Study Details

NCT05552755Recruiting

Evaluate REC-4881 in Patients With FAP

This is a multicenter, two-part trial in participants with Familial Adenomatous Polyposis (FAP)....

St Louis, MOPHASE167 participantsRecursion Pharmaceuticals Inc.

View Study Details

NCT07040904Recruiting

Mindfulness to Enhance Cognitive Health in Latino Older Adults

The primary objective of the proposed research is to investigate the promise and underlying mechanisms of mindfulness training as a preventative lifestyle intervention to enhance cognitive health in L...

St Louis, MONA60 participantsWashington University School of Medicine

View Study Details

NCT06985147Recruiting

A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

This open-label, multicenter, within-participant dose escalation study examining up to 2 dose levels of DISC-3405 will assess the safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics...

St Louis, MOPHASE260 participantsDisc Medicine, Inc

View Study Details

NCT07313592Recruiting

Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients

This is a prospective specimen collection study evaluating the feasibility of using the ChromoSeq® assay for upfront classification in a real-time clinical setting of pediatric and young adult acute l...

St Louis, MO60 participantsWashington University School of Medicine

View Study Details

NCT07089121Recruiting

Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders

Safety, tolerability and efficacy of Descarte-08 in children, adolescents and young adults with childhood-onset systemic lupus erythematosus, ANCA-associated vasculitis, juvenile myasthenia gravis, an...

St Louis, MOPHASE150 participantsCartesian Therapeutics

View Study Details

NCT06529731Recruiting

Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation

This phase 2 study aims to confirm the efficacy seen in the prior phase 1 trial, and further contribute to this effort through the collection of leukemia cells pre- and post- in vivo IFN-γ therapy. As...

St Louis, MOPHASE245 participantsSawa Ito, MD

View Study Details

NCT07137416Recruiting

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

This phase I trial tests the safety, side effects, and best dose of pidnarulex in combination with trastuzumab deruxtecan in treating patients with breast cancer and other solid tumors that express va...

St Louis, MOPHASE136 participantsNational Cancer Institute (NCI)

View Study Details

NCT07473102Recruiting

PET Imaging of MMP Activation in AAA: Clinical Component

A first-in-human evaluation of \[64Cu\]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoi...

St Louis, MOEARLY_PHASE128 participantsWashington University School of Medicine

View Study Details

NCT07295847Recruiting

A Study of AZD0120 in Autoimmune Diseases

This trial is a Phase 1b, open-label, multi-center, clinical study of AZD0120, a BCMA/CD19 dual targeting CAR+ T-cell therapy, to evaluate the safety and tolerability in adult participants with system...

St Louis, MOPHASE127 participantsAstraZeneca

View Study Details

NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

St Louis, MOPHASE120 participantsAdaptimmune

View Study Details

NCT06240754Recruiting

Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial

Study researchers think that a drug called enasidenib may help people with clonal cytopenia of undetermined significance (CCUS) because the drug blocks the mutated IDH2 protein, which may improve bloo...

St Louis, MOPHASE215 participantsWashington University School of Medicine

View Study Details

About Heart Attack Clinical Trials in St Louis

A heart attack (myocardial infarction) occurs when blood flow to part of the heart muscle is blocked, usually by a blood clot. It is a medical emergency requiring immediate treatment. Long-term management includes medications, lifestyle changes, and cardiac rehabilitation.

There are currently 25 heart attack clinical trials recruiting participants in St Louis, MO. These studies are seeking a combined 6,650 participants. Research is being sponsored by Alexion Pharmaceuticals, Inc., Boston Children's Hospital, Amrou Sarraj and 16 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Attack Clinical Trials in St Louis — FAQ

Are there heart attack clinical trials in St Louis?

Yes, there are 25 heart attack clinical trials currently recruiting in St Louis, MO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in St Louis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.

Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.

What heart attack treatments are being tested?

The 25 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for heart attack.

Data updated July 18, 2026 from ClinicalTrials.gov