30 Pulmonary Embolism Clinical Trials in St Louis, MO (2026)

Q: How do I join a clinical trial in St Louis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you.

Recruiting Pulmonary Embolism Studies in St Louis

NCT03141021Recruiting

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

First, the investigators plan to use a retrospective analysis to determine the clinical landscape of neurofibromatosis (NF)1-associated malignant peripheral nerve sheath tumor (MPNST) and precursor le...

St Louis, MO1,050 participantsWashington University School of Medicine

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NCT04629014Recruiting

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

This study proposes to quantify and describe the quality of life of children with intestinal failure, and to identify the medical and socio-economic factors that impact this quality of life, using dat...

St Louis, MO750 participantsBoston Children's Hospital

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NCT06121011Recruiting

A Global Prospective Observational Registry of Patients With Pompe Disease

This is a global, multicenter, prospective, observational registry of patients with Pompe disease, including those with late-onset pompe disease (LOPD) and infantile-onset pompe disease (IOPD). Both u...

St Louis, MO500 participantsAmicus Therapeutics

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NCT06880770Recruiting

Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

This study will evaluate the efficacy and safety of plozasiran in approximately 140 adult participants with severe hypertriglyceridemia (SHTG) and history of at least two prior acute pancreatitis (AP)...

St Louis, MOPHASE3288 participantsArrowhead Pharmaceuticals

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NCT07265947Recruiting

Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial Carcinoma

A Phase 2A/B study of Dabogratinib (TYRA-300) in Low Grade Upper Tract Urothelial Carcinoma...

St Louis, MOPHASE2230 participantsTyra Biosciences, Inc

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NCT06777901Recruiting

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

The goal of this clinical trial is to learn if the Auryon Atherectomy System with balloon angioplasty safe and effective in treating lower limb blockages. The main question it aims to answer is: Is tr...

St Louis, MOPHASE4224 participantsAngiodynamics, Inc.

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NCT06023225Recruiting

Sex Hormones, Postoperative Pain and Opioid Use

Aim 1- To identify relationships between sex hormone levels and postoperative pain and opioid use. Aim 2: To determine whether the effects of testosterone on postoperative pain and opioid use are med...

St Louis, MO210 participantsWashington University School of Medicine

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NCT07293689Recruiting

PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

The goal of this observational study is to learn about how the doctor decides how long to cut t the esophageal muscle during Per-Oral Endoscopic Myotomy (POEM) in patients with difficulty swallowing d...

St Louis, MO200 participantsNorthwestern University

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NCT03546374Recruiting

Medtronic Terminate AF Study

The purpose of this study is to demonstrate the safety and effectiveness of the Cardioblate iRF and CryoFlex hand held devices for the treatment of non-paroxysmal atrial fibrillation (AF)....

St Louis, MONA160 participantsMedtronic Cardiac Surgery

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NCT07540897Recruiting

A Study to Evaluate the Efficacy, Safety and Tolerability of ALKS 2680 in Adults With Narcolepsy Type 1 (Brilliance NT1 - 304)

The purpose of this study is to measure decreases in daytime sleepiness, cataplexy (sudden loss of muscle tone), and disease symptoms in participants with NT1 when taking ALKS 2680 tablets compared wi...

St Louis, MOPHASE3150 participantsAlkermes, Inc.

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NCT06217302Recruiting

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Wheth...

St Louis, MOPHASE3150 participantsAlessandro Doria

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NCT03813407Recruiting

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

Sodium zirconium cyclosilicate has been shown to be effective and safe in adults for the treatment of hyperkalaemia, and therefore it is expected to be beneficial in children. This study will evaluate...

St Louis, MOPHASE3140 participantsAstraZeneca

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NCT06101303Recruiting

Endometriosis Pain

Aim 1. To determine the factors contributing to pain in patients with chronic pelvic pain with and without endometriosis Aim 2. To determine the changes following endometriosis lesion removal surgery ...

St Louis, MO120 participantsWashington University School of Medicine

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NCT05481879Recruiting

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

The primary purpose of the study is to evaluate the safety and tolerability of multiple intravenous (IV) doses of DYNE-101 administered to participants with Myotonic Dystrophy Type 1 (DM1). The study...

St Louis, MOPHASE1116 participantsDyne Therapeutics

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NCT06997588Recruiting

EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

This study is designed to demonstrate the efficacy and assess safety and tolerability of oral daily alpelisib in participants with PIK3CA-related overgrowth spectrum (PROS)....

St Louis, MOPHASE2104 participantsNovartis Pharmaceuticals

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NCT05088798Recruiting

Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism

The purpose of the study is to provide access to 18F-DOPA PET to patients at Washington University and assess the utility of 18F-DOPA PET/MRI as a preoperative tool to detect and localize focal lesion...

St Louis, MOPHASE2100 participantsWashington University School of Medicine

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NCT06949826Recruiting

Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery

Addictive full-agonist opioids, like oxycodone and hydrocodone, are often used to treat pain after surgery. However, these full-agonist opioids can be very addictive. After ankle fracture surgery, abo...

St Louis, MOPHASE4100 participantsJenna-Leigh Wilson

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NCT06812078Recruiting

A Study of TAK-360 in Adults With Idiopathic Hypersomnia

Idiopathic Hypersomnia (IH) is a condition where people feel extremely sleepy during the day, especially in the morning, even if they sleep a lot at night. They may have trouble waking up in the morni...

St Louis, MOPHASE296 participantsTakeda

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NCT07062588Recruiting

Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN)

This study will determine the effect of treatment of AGA2115 in adults with Type I, III, or IV osteogenesis imperfecta versus placebo....

St Louis, MOPHASE280 participantsAngitia Incorporated Limited

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NCT06057935Recruiting

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

The purpose of this study is to find out whether intraperitoneal or intravenous chemotherapy given after cytoreductive surgery and HIPEC are effective treatments for people with malignant peritoneal m...

St Louis, MOPHASE264 participantsMemorial Sloan Kettering Cancer Center

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NCT06503809Recruiting

Efficacy and Safety of a Ketogenic Diet in Type 1 Diabetes

Despite strong evidence that tight control of blood sugar reduces the risk of diabetes complications, most people with type 1 diabetes do not achieve recommended blood sugar targets. This randomized c...

St Louis, MONA58 participantsWashington University School of Medicine

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NCT05634369Recruiting

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

The purpose of this study is to determine if the addition of infusions of a type of immune cell called a "natural killer", or NK cell to the sarcoma chemotherapy regimen GEM/DOX (gemcitabine and docet...

St Louis, MOPHASE150 participantsNationwide Children's Hospital

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NCT07123155Recruiting

Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)

The purpose of this study is to evaluate the safety, pharmacodynamics (PD), and exploratory clinical efficacy of S-606001 in adult participants with LOPD as an add-on to ERT....

St Louis, MOPHASE245 participantsShionogi

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NCT06830096Recruiting

Role of KATP Channel Loss in Type 2 Diabetes

Insulin is a hormone that is made by β-cells in the pancreas and when released into the bloodstream helps control blood sugar levels. Insulin release is regulated by electrical activity in the β-cell ...

St Louis, MONA40 participantsWashington University School of Medicine

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NCT07278778Recruiting

Cancer Care Companion

This study invites parents of children with cancer to use an electronic health record (EHR)-based communication tool, called the Cancer Care Companion, and assess the acceptability, appropriateness, a...

St Louis, MONA40 participantsWashington University School of Medicine

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NCT07226453Recruiting

Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

This is a multi-site study of the pharmacodynamic effects and efficacy of metformin in children and young adults with recurrent or progressive Posterior Fossa Group A (PFA) ependymoma....

St Louis, MOPHASE230 participantsUniversity of California, San Francisco

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NCT06541847Recruiting

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

The trial will be an open label, single arm, phase 2 study in 20 participants. The study will assess the tolerability and efficacy of HLX-1502 in participants with NF1 16 years of age or older with pr...

St Louis, MOPHASE225 participantsHealx Limited

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NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

St Louis, MOPHASE120 participantsAdaptimmune

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NCT00567073Recruiting

Pompe Pregnancy Sub-Registry

This Sub-registry is a multicenter, international, longitudinal, observational, and voluntary program designed to track pregnancy outcomes for any pregnant woman enrolled in the Pompe Registry, regard...

St Louis, MO20 participantsGenzyme, a Sanofi Company

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NCT03988283Recruiting

Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors

The purpose of this research study is to learn about the safety and feasibility of giving a personalized DNA vaccine to people with central nervous system tumors that have returned or have been resist...

St Louis, MOPHASE17 participantsWashington University School of Medicine

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About Pulmonary Embolism Clinical Trials in St Louis

Pulmonary embolism (PE) is a blockage of an artery in the lungs, usually caused by blood clots that travel from the deep veins of the legs. It can be life-threatening and requires immediate medical attention. Treatment includes anticoagulants and in severe cases, thrombolytic therapy.

There are currently 30 pulmonary embolism clinical trials recruiting participants in St Louis, MO. These studies are seeking a combined 5,167 participants. Research is being sponsored by Washington University School of Medicine, Boston Children's Hospital, Amicus Therapeutics and 20 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Embolism Clinical Trials in St Louis — FAQ

Are there pulmonary embolism clinical trials in St Louis?

Yes, there are 30 pulmonary embolism clinical trials currently recruiting in St Louis, MO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in St Louis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.

Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.

What pulmonary embolism treatments are being tested?

The 30 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary embolism.

Data updated July 18, 2026 from ClinicalTrials.gov