St Louis, MO14 Active Studies

Pulmonary Embolism Clinical Trials in St Louis, MO

Find 14 actively recruiting pulmonary embolism clinical trials in St Louis, MO. Connect with local research sites and explore new treatment options.

14
Active Trials
14
Sponsors
1,753
Enrolling

Recruiting Pulmonary Embolism Studies in St Louis

RecruitingSt Louis, MONCT05018585

A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes

The objective of DIAGNODE-3 is to evaluate the efficacy and safety of three intranodal injections of 4 μg of Diamyd compared to placebo, along with oral Vitamin D supplementation, to preserve endogeno...

330 participants
Diamyd Medical AB
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RecruitingSt Louis, MONCT06789913

A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation

This is a 3-part Phase 2 randomized study evaluating the safety and efficacy of the mutant-selective PI3Kα inhibitor, RLY-2608, in adults and children with PIK3CA Related Overgrowth Spectrum (PROS) an...

277 participants
Relay Therapeutics, Inc.
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RecruitingSt Louis, MONCT06777901

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

The goal of this clinical trial is to learn if the Auryon Atherectomy System with balloon angioplasty safe and effective in treating lower limb blockages. The main question it aims to answer is: Is tr...

224 participants
Angiodynamics, Inc.
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RecruitingSt Louis, MONCT06056297

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

The purpose of this study is to demonstrate the efficacy and evaluate the safety and tolerability of mavorixafor in participants with congenital or acquired primary autoimmune and idiopathic chronic n...

150 participants
X4 Pharmaceuticals
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RecruitingSt Louis, MONCT06217302

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Wheth...

150 participants
Alessandro Doria
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RecruitingSt Louis, MONCT03813407

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

Sodium zirconium cyclosilicate has been shown to be effective and safe in adults for the treatment of hyperkalaemia, and therefore it is expected to be beneficial in children. This study will evaluate...

140 participants
AstraZeneca
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RecruitingSt Louis, MONCT06797869

A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy

This study will look at the effects of CagriSema in people with both type 2 diabetes and painful diabetic peripheral neuropathy, compared to placebo. Participants will either get an active medicine or...

134 participants
Novo Nordisk A/S
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RecruitingSt Louis, MONCT06340451

Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity

This multicenter, randomized, double-blind, sham-controlled study is designed to evaluate the efficacy and safety of the iovera° system in subjects with upper extremity spasticity. A total of approxim...

132 participants
Pacira Pharmaceuticals, Inc
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RecruitingSt Louis, MONCT06057935

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

The purpose of this study is to find out whether intraperitoneal or intravenous chemotherapy given after cytoreductive surgery and HIPEC are effective treatments for people with malignant peritoneal m...

64 participants
Memorial Sloan Kettering Cancer Center
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RecruitingSt Louis, MONCT05634369

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

The purpose of this study is to determine if the addition of infusions of a type of immune cell called a "natural killer", or NK cell to the sarcoma chemotherapy regimen GEM/DOX (gemcitabine and docet...

50 participants
Nationwide Children's Hospital
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RecruitingSt Louis, MONCT06812078

A Study of TAK-360 in Adults With Idiopathic Hypersomnia

Idiopathic Hypersomnia (IH) is a condition where people feel extremely sleepy during the day, especially in the morning, even if they sleep a lot at night. They may have trouble waking up in the morni...

40 participants
Takeda
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RecruitingSt Louis, MONCT03911505

ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD

This is a Phase 3, open-label, multicenter study to evaluate the safety, PK, efficacy, PD, and immunogenicity of Cipaglucosidase Alfa/Miglustat treatment in enzyme replacement therapy (ERT)-experience...

22 participants
Amicus Therapeutics
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RecruitingSt Louis, MONCT06541847

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

The trial will be an open label, single arm, phase 2 study in 20 participants. The study will assess the tolerability and efficacy of HLX-1502 in participants with NF1 16 years of age or older with pr...

20 participants
Healx Limited
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RecruitingSt Louis, MONCT05642455

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

20 participants
Adaptimmune
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About Pulmonary Embolism Clinical Trials in St Louis

Pulmonary embolism (PE) is a blockage of an artery in the lungs, usually caused by blood clots that travel from the deep veins of the legs. It can be life-threatening and requires immediate medical attention. Treatment includes anticoagulants and in severe cases, thrombolytic therapy.

There are currently 14 pulmonary embolism clinical trials recruiting participants in St Louis, MO. These studies are seeking a combined 1,753 participants. Research is being sponsored by Diamyd Medical AB, Relay Therapeutics, Inc., Angiodynamics, Inc. and 11 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Embolism Clinical Trials in St Louis — FAQ

Are there pulmonary embolism clinical trials in St Louis?

Yes, there are 14 pulmonary embolism clinical trials currently recruiting in St Louis, MO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in St Louis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.

Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.

What pulmonary embolism treatments are being tested?

The 14 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary embolism.

Data updated March 2, 2026 from ClinicalTrials.gov