Murray, UTNCT07558265Now EnrollingIRB Ready

Acute Hypoxic Respiratory Failure Clinical Trial in Murray, UT

Access cutting-edge acute hypoxic respiratory failure treatment through this clinical trial at a research site in Murray. Study-provided care at no cost to qualified participants.

Sponsored by Ohio State University

Quick Self-Assessment

See if you qualify for this Murray location

Preparing your pre-screening questions…

Expert Care in Murray

Access acute hypoxic respiratory failure specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related acute hypoxic respiratory failure treatment provided free

Apply for This Murray Location

Check if you qualify for this acute hypoxic respiratory failure clinical trial in Murray, UT

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Murray

    Convenient for UT residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Murray site if eligible
  4. 4Begin participation

About This Acute Hypoxic Respiratory Failure Study in Murray

The purpose of this clinical trial is to determine the best initial non-invasive respiratory support (NIRS) strategy for adults who present to the emergency department with acute hypoxemic respiratory failure, a condition in which blood oxygen levels are dangerously low and require urgent treatment. This study compares two commonly used non-invasive respiratory support strategies to evaluate their effectiveness and safety, based on important patient outcomes during hospitalization, including survival, the need for invasive mechanical ventilation, and the duration of respiratory support. Participants will be randomly assigned (with an equal chance) to receive one of the following treatments: * Non-Invasive Positive Pressure Ventilation (NIPPV): Oxygen delivered under pressure through a face mask. * High-Flow Nasal Oxygen (HFNO): Oxygen delivered at high-flow through a specially designed nasal cannula placed in the nostrils. Researchers will compare the two treatment strategies using a hierarchical assessment of major pulmonary outcomes, including: * Hospital survival * Days on mechanical ventilation * Duration of non-invasive respiratory support As part of the study, researchers will collect: * Blood and urine samples * Physiologic measurements (such as chest movement measured through sensors placed on the skin) * Information from participants' medical records

Sponsor: Ohio State University

Who Can Participate

Inclusion Criteria

Age ≥18 years
Presenting to the Emergency Department (ED) with Acute Hypoxemic Respiratory failure (AHRF), defined as:
\[(respiratory rate ≥25 breaths/min) AND (requiring ≥6 L/min of oxygen required to maintain SpO2 ≥90%), OR SpO2:FiO2 ratio\<250\] OR
Arrival at ED on prehospital Non-Invasive Respiratory Support (NIRS).
Clinical need for NIRS
Randomization ≤2 hours after identification of need for NIRS
Randomization ≤6 hours of ED arrival

Exclusion Criteria

Urgent need for intubation
Cardiac arrest
Respiratory arrest
Patient not located in the ED
Craniofacial anatomic features that prohibit either Non-Invasive Positive Pressure Ventilation (NIPPV) or High Flow Nasal Oxygen (HFNO) interface
Tracheostomy or laryngectomy stoma
Hemodynamic instability requiring \>0.2mcg/kg/min of norepinepherine (or equivalent) to maintain mean arterial pressure \>65mmHg
Pre-existing "do not resuscitate" or "do not intubate" order
Home use of non-invasive positive-pressure ventilation for respiratory support of a medical condition other than sleep apnea
Transferred from another Emergency Department
History of advanced chronic obstructive pulmonary disease
History of advanced heart failure
Presence of opt-out identification
Known or apparent pregnant
Previous enrollment in WINDSURFER
A patient-specific contraindication makes one assigned study intervention unsafe

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Murray?

Yes, this clinical trial (NCT07558265) has an active research site in Murray, UT that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Acute Hypoxic Respiratory Failure Treatment Options in Murray, UT

If you're searching for acute hypoxic respiratory failure treatment options in Murray, UT, this clinical trial (NCT07558265) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Murray research site is actively enrolling participants for this clinical trial. You'll receive care from experienced acute hypoxic respiratory failure specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all acute hypoxic respiratory failure clinical trials near you to find additional studies recruiting in your area.

More Rheumatoid Arthritis Trials in Murray, UT

See all rheumatoid arthritis clinical trials recruiting in Murray — not just this study.

Browse Rheumatoid Arthritis Trials in Murray →

Ready to Join in Murray?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Murray, UT