Fairfax, VANCT07723703Now EnrollingIRB Ready

Acute Myeloid Leukaemia Clinical Trial in Fairfax, VA

Access cutting-edge acute myeloid leukaemia treatment through this phase 1 clinical trial at a research site in Fairfax. Study-provided care at no cost to qualified participants.

Sponsored by Amphista Therapeutics Ltd

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Expert Care in Fairfax

Access acute myeloid leukaemia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related acute myeloid leukaemia treatment provided free

Apply for This Fairfax Location

Check if you qualify for this acute myeloid leukaemia clinical trial in Fairfax, VA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Fairfax

    Convenient for VA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Fairfax site if eligible
  4. 4Begin participation

About This Acute Myeloid Leukaemia Study in Fairfax

The purpose of the study is to assess the safety, pharmacokinetics, and preliminary efficacy of AMX-883 monotherapy in participants with acute myeloid leukaemia (AML) and high-risk myelodysplastic syndrome (MDS) and in combination with anticancer agents in participants with AML.

Sponsor: Amphista Therapeutics Ltd

Who Can Participate

Inclusion Criteria

Participants with relapsed or refractory AML who have failed all available standard therapies or relapsed or refractory high-risk MDS with BM blasts 10-19%
Eastern Cooperative Oncology Group (ECOG) performance status of 0-2
Adequate washout from prior therapies
Adequate kidney and liver function
Female participants of childbearing potential must use highly effective contraception, and male participants must agree to use barrier contraception and avoid sperm donation for at least 120 days after last dose
If enrolled in M1B: Participant must have no documented contraindication to treatment with posaconazole before start of treatment

Exclusion Criteria

Diagnosis of acute promyelocytic leukaemia or chronic myelogenous leukaemia in blast crisis
Clinically active central nervous system (CNS) leukaemia
Receiving immunosuppressive therapy post HSCT
History of another malignancy that is active, progressing, or has required systemic treatment within the past 2 years
Presence of \>Grade 1 active graft versus host disease within 4 weeks prior to C1D1
Significant cardiovascular disease
Family history of sudden cardiac death before 40 years of age or a family history of long QT syndrome
Clinically significant electrolyte imbalances (e.g., hypokalaemia, hypomagnesaemia, hypocalcaemia) that may contribute to QT interval prolongation
Clinically significant bradycardia (\<50 beats per minute) that is symptomatic or causes haemodynamic instability
Major surgery within 4 weeks prior to C1D1 or inadequate recovery from prior surgery
Uncontrolled intercurrent illness
Inability to fast, swallow, ingest, or absorb oral medication due to a pre-existing condition
History of interstitial lung disease or pneumonitis requiring systemic corticosteroid treatment
Requirement for medications with a known risk of Torsades de Pointes that cannot be discontinued prior to study treatment
Detectable human immunodeficiency virus (HIV) viral load
Known serologic status reflecting active hepatitis B or C infection
Active uncontrolled systemic fungal, bacterial, viral, or other infection or a condition predisposing to severe infection

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Fairfax?

Yes, this clinical trial (NCT07723703) has an active research site in Fairfax, VA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Acute Myeloid Leukaemia Treatment Options in Fairfax, VA

If you're searching for acute myeloid leukaemia treatment options in Fairfax, VA, this clinical trial (NCT07723703) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Fairfax research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced acute myeloid leukaemia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all acute myeloid leukaemia clinical trials near you to find additional studies recruiting in your area.

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