Aurora, CONCT07584226Now EnrollingIRB Ready

Advanced NRAS-Mutant Melanoma Clinical Trial in Aurora, CO

Access cutting-edge advanced nras-mutant melanoma treatment through this clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by Relay Therapeutics, Inc.

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Expert Care in Aurora

Access advanced nras-mutant melanoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related advanced nras-mutant melanoma treatment provided free

Apply for This Aurora Location

Check if you qualify for this advanced nras-mutant melanoma clinical trial in Aurora, CO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This Advanced NRAS-Mutant Melanoma Study in Aurora

This is a Phase 1 first-in-human, open-label multicenter study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of RLY-8161, an NRAS-selective inhibitor, in participants with advanced NRAS-mutant melanoma and other solid tumors.

Sponsor: Relay Therapeutics, Inc.

Who Can Participate

Inclusion Criteria

Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 1.
Histologically confirmed diagnosis of unresectable Stage III or IV melanoma or other solid tumor.
Disease is refractory to standard therapy (including targeted therapy), participant is intolerant of standard therapy, or participant has declined standard therapy.
Measurable disease per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1.
One or more documented primary oncogenic NRAS mutation(s).

Exclusion Criteria

Known activating KRAS, HRAS, or BRAF mutation or known alterations in other driver oncogenes.
Prior treatment with ERK, MEK, RAF, or RAS targeting agents or any agent whose mechanism of action is to inhibit the RAS-MAPK pathway.
For participants with melanoma: lactate dehydrogenase (LDH) \>2×ULN.
Central nervous system (CNS) metastases that are associated with progressive neurologic symptoms or require ongoing corticosteroids to control the CNS disease.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT07584226) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Advanced NRAS-Mutant Melanoma Treatment Options in Aurora, CO

If you're searching for advanced nras-mutant melanoma treatment options in Aurora, CO, this clinical trial (NCT07584226) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced advanced nras-mutant melanoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all advanced nras-mutant melanoma clinical trials near you to find additional studies recruiting in your area.

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Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Aurora, CO