Boston, MANCT06292780Now EnrollingIRB Ready

AL Amyloidosis Clinical Trial in Boston, MA

Access cutting-edge al amyloidosis treatment through this phase 1/2 clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Regeneron Pharmaceuticals

Quick Self-Assessment

See if you qualify for this Boston location

Preparing your pre-screening questions…

Expert Care in Boston

Access al amyloidosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related al amyloidosis treatment provided free

Apply for This Boston Location

Check if you qualify for this al amyloidosis clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This AL Amyloidosis Study in Boston

This study is researching an experimental drug called linvoseltamab ("study drug"). This study is focused on patients who have AL amyloidosis that has returned or have failed other therapies and need to be treated again. The study consists of 2 phases (Phase 1 and Phase 2): * In Phase 1, linvoseltamab will be given to a small number of participants to study the side effects of the study drug and to determine the recommended doses of the study drug to be given to participants in Phase 2. * In

Sponsor: Regeneron Pharmaceuticals

Who Can Participate

Inclusion Criteria

Confirmed diagnosis of AL amyloidosis, as described in the protocol
Measurable disease as defined by serum difference between involved and uninvolved free light chains (dFLC) concentration, as described in the protocol
Previously treated after at least 1 prior therapy and requiring further treatment as assessed by the Investigator
N-terminal pro b-type natriuretic peptide (NT-proBNP) ≤8500 ng/L during screening
Adequate hepatic, hematologic, renal, and cardiac function, as described in the protocol
Eastern Cooperative Oncology Group (ECOG) performance score ≤2 at screening Key

Exclusion Criteria

History of other non-AL amyloidosis
Greater than 60% plasmacytosis on a bone marrow biopsy and/or aspirate during screening
Presence of lytic bone lesion(s) or extramedullary plasmacytoma on imaging during screening
Myocardial infarction within the past 6 months prior to the first screening visit
Known active infection requiring hospitalization or treatment with IV anti-infectives within 28 days of first administration of study drug NOTE: Other protocol defined inclusion/exclusion criteria apply

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT06292780) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

AL Amyloidosis Treatment Options in Boston, MA

If you're searching for al amyloidosis treatment options in Boston, MA, this clinical trial (NCT06292780) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced al amyloidosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all al amyloidosis clinical trials near you to find additional studies recruiting in your area.

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See all amyloidosis clinical trials recruiting in Boston — not just this study.

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