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NCT06302413 · Indiana University

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What this study is about

The goal of this clinical trial is to use a novel virtual reality intervention to test for effectiveness in reducing alcohol use and increasing abstinence, with concomitant increases in future self-identification, future time perspective, and delay-of-reward, in early recovering alcohol use disorder (AUD) persons.

View original scientific description

The goal of this clinical trial is to use a novel virtual reality intervention to test for efficacy in reducing alcohol use and increasing abstinence, with concomitant increases in future self-identification, future time perspective, and delay-of-reward, in early recovering alcohol use disorder (AUD) persons. The main question\[s\] this trial aims to answer are: Will the Virtual Reality (VR) intervention decrease the number of stimulant use days? Will the VR intervention produce longer abstinence periods during follow-up visits? Will the VR intervention increase alcohol abstinence rates? Will the VR intervention increase future self-identification? Will the VR intervention increase self-reported future time perspective? Will the VR intervention increase preference for delayed rewards in a laboratory delay discounting task on the study day? Will the VR intervention produce gains in the behavioral effects of future self-identification, future time perspective, and delayed rewards at the 30-day and 6-month follow-ups? Researchers will compare the experimental and control groups to see if there are differences in the results for the questions outlined above.

Interventions

DEVICE

Virtual Reality

They will receive a Virtual Reality Park experience, which is an empty park with no avatars. They will then have a Virtual Reality Avatar experience, where they will see an avatar resembling themselves in a park setting.

DEVICE

Virtual Reality

They will receive a Virtual Reality Park experience, which is an empty park with no avatars.

Primary outcome measures

Reduced Use of Drug Using Days

Time frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit

The Virtual Reality Avatar experience will reduce drug using days.

Increased Length of Abstinence

Time frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.

The Virtual Reality Avatar experience will increase the length of abstinence periods.

Increased (overall) Abstinence

Time frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.

The Virtual Reality Avatar experience will increase abstinence.

Future Self-identification with Future Self Continuity Questionnaire

Time frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit

The Virtual Reality Avatar experience will increase future self-identification.

Future Time Perspective with the Delayed Discounting Behavioral Task and Future Self Continuity Questionnaire

Time frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.

The Virtual Reality Avatar experience will increase future time perspective.

Delayed Reward Preference with the Delayed Discounting Behavioral Task

Time frame: Day 2-Study Day Visit; 30-day Follow-up Visit; 6-month Follow-up Visit.

The Virtual Reality Avatar experience will increase preference for delayed rewards.

Who can participate

This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.

Inclusion criteria

  • Abstinence between ≥14 days and ≤1 year
  • Verbal endorsement of commitment to recovery
  • Psychotropic drugs for SUD-comorbidity
  • Drug/alcohol abstinence ≥ 24 hours at the time of the study day visit
  • English comprehension

Exclusion criteria

  • Unstable medical disorders
  • Habitual drug use
  • Mu-opioid drugs
  • Smell/taste disorders
  • Unstable psychiatric conditions
  • Extravagant/elaborate face tattoos

Where

  • Indianapolis, Indiana

Collaborators

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Related conditions & keywords

Alcohol Use Disorder

Frequently asked questions

What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Data: ClinicalTrials.gov · synced May 4, 2026 · Source of record for eligibility and locations

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1 of 500 participants interested
0% interest

See if this study fits

A short prescreen based on this study's listed criteria. A coordinator confirms eligibility — this is not a medical assessment.

Preparing your pre-screening questions…

Study locations

Choose your preferred location, or select flexible during enrollment.

Available
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Virtual Participation

Participate from home

Remote participation via telemedicine and home visits

RECRUITING

Indianapolis

Indiana

Location available

Express your interest

Share your contact details and a study coordinator can follow up about screening.

Secure & Confidential

Your information is protected and will only be shared with the research team.

What participation can include

  • Study-related care provided by the research team
  • Close monitoring by medical professionals
  • Possible compensation for time and travel*
  • The option to withdraw at any time
  • Contributing to medical research that may help future patients

*Compensation varies by study. Confirm details with coordinator.

Typical next steps

  1. 1.Submit this form
  2. 2.Phone screening
  3. 3.In-person assessment if eligible
  4. 4.Begin participation

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Looking for Alcohol Use Disorder Treatment in Indianapolis?

Join others in Indiana exploring innovative treatment options through clinical research

Alcohol Use Disorder Treatment Options in Indianapolis, Indiana

If you're searching for Alcohol Use Disorder treatment in Indianapolis, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Indianapolis and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Alcohol Use Disorder. All study-related care is provided at no cost to participants.

Local Sites
1 locations in Indiana
Now Enrolling
Up to 500 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Alcohol Use Disorder?

Potential Benefits

  • Access to new treatment approaches before public availability
  • Close monitoring by experienced medical professionals
  • Study-related care provided at no cost
  • Contribute to medical research for Alcohol Use Disorder

What to Expect

  • Initial screening to determine eligibility
  • Regular check-ups and monitoring visits
  • Possible compensation for time and travel
  • You can withdraw at any time

Frequently Asked Questions About This Alcohol Use Disorder Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT06302413. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.