Rochester, NYNCT06319872Now EnrollingIRB Ready

Alcohol Use Disorder Clinical Trial in Rochester, NY

Access cutting-edge alcohol use disorder treatment through this clinical trial at a research site in Rochester. Study-provided care at no cost to qualified participants.

Sponsored by University of Rochester

Quick Self-Assessment

See if you qualify for this Rochester location

Preparing your pre-screening questionsā€¦

Expert Care in Rochester

Access alcohol use disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related alcohol use disorder treatment provided free

Apply for This Rochester Location

Check if you qualify for this alcohol use disorder clinical trial in Rochester, NY

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Rochester

    Convenient for NY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Rochester site if eligible
  4. 4Begin participation

About This Alcohol Use Disorder Study in Rochester

Oral disulfiram (AntabuseĀ®) has been shown to improve image-forming vision in animal models with retinal degeneration due to its ability to decrease Retinoic Acid synthesis and consequently reduce hyperactivity in the inner retina. The investigator will aim to evaluate the impact of oral disulfiram on the vision of patients with retinal degeneration who are being treated with the drug in the management of their concurrent alcohol use disorder.

Sponsor: University of Rochester

Who Can Participate

Inclusion Criteria

All sexes, 18 years and older.
Participants must speak English, understand, and sign the informed consent document.
Stated willingness to comply with all study procedures and availability for the duration of the study.
In good general health as evidenced by medical history and with a clinical diagnosis of inherited retinal dystrophy or dry-AMD.
Best Corrected Visual Acuity (BCVA) of 20/20 (with constriction or other defects of Goldmann visual field) to Light Perception in the better eye.
Intact inner nuclear layer, inner plexiform, and ganglion cell layer on macular SD-OCT.
Ability to take oral medication and be willing to adhere to the disulfiram regimen.
Patients must have the diagnosis of alcohol use disorder provided by an addiction specialist and be a candidate for therapeutic use of disulfiram for that condition.
Patients must agree to refrain from all alcohol consumption for 180 days.
Any female participant of childbearing potential must have a negative urine pregnancy test at screening.
Any female participant of childbearing potential must have (or have a partner who has) had a surgical sterilization (vasectomy, hysterectomy, or tubal ligation), be completely abstinent from intercourse or must agree to practice two acceptable methods of contraception throughout the course of the study and for at least one week after disulfiram discontinuation. Acceptable methods of contraception include hormonal contraception (i.e., birth control pills, injected hormones, dermal patch, or vaginal ring); intrauterine device; barrier methods (diaphragm, condom) with spermicide.

Exclusion Criteria

A condition that, in the opinion of the investigator, would preclude participation in the study, e.g., cardiovascular disease, hepatitis.
Individuals with a history of diabetes mellitus.
Individuals with a history of psychosis.
Individuals with hypothyroidism.
Individuals with hypersensitivity to thiuram derivatives causing rubber contact dermatitis.
Those on anticoagulant therapy or other medications that may be affected by disulfiram.
Ophthalmic conditions with independent effect upon visual function (e.g. diabetic retinopathy, glaucoma, cataract, vitreous hemorrhage, retinal detachment, active intraocular inflammation or active infectious ocular diseases, choroidal neovascularization).
Patients with No Light Perception (NLP) in both eyes.
History of major ocular surgery within the prior 6 months or major ocular surgery anticipated within the next 6 months following randomization.
Exam evidence of severe external ocular infection, including conjunctivitis, chalazion, or substantial blepharitis
Participation in an investigational trial that involves treatment with any drug within 30 days of randomization that has not received regulatory approval at the time of study entry. Note: study participants cannot receive another investigational drug while participating in this study.
Known allergy or hypersensitivity to any component of the study drug.
For women of child-bearing potential: pregnant or lactating or intending to become pregnant within the next 12 months.
Participants who expect to move out of the area of the clinical center during the 8 months of the study

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Rochester?

Yes, this clinical trial (NCT06319872) has an active research site in Rochester, NY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Alcohol Use Disorder Treatment Options in Rochester, NY

If you're searching for alcohol use disorder treatment options in Rochester, NY, this clinical trial (NCT06319872) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Rochester research site is actively enrolling participants for this clinical trial. You'll receive care from experienced alcohol use disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all alcohol use disorder clinical trials near you to find additional studies recruiting in your area.

More Substance Use Disorder Trials in Rochester, NY

See all substance use disorder clinical trials recruiting in Rochester ā€” not just this study.

Browse Substance Use Disorder Trials in Rochester ā†’

Browse More Trials by Condition

Substance Use Disorder TrialsAll Conditions ā†’

Ready to Join in Rochester?

Take the first step toward participating in this groundbreaking clinical trial

Secure Ā· Expert Care Ā· Rochester, NY