Jamaica Plain, MANCT06727331Now EnrollingIRB Ready

Alcohol Use Disorder Clinical Trial in Jamaica Plain, MA

Access cutting-edge alcohol use disorder treatment through this phase 2 clinical trial at a research site in Jamaica Plain. Study-provided care at no cost to qualified participants.

Sponsored by Brigham and Women's Hospital

Quick Self-Assessment

See if you qualify for this Jamaica Plain location

Preparing your pre-screening questions…

Expert Care in Jamaica Plain

Access alcohol use disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related alcohol use disorder treatment provided free

Apply for This Jamaica Plain Location

Check if you qualify for this alcohol use disorder clinical trial in Jamaica Plain, MA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Jamaica Plain

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Jamaica Plain site if eligible
  4. 4Begin participation

About This Alcohol Use Disorder Study in Jamaica Plain

This is a pilot, 4-week, double-blind, placebo-controlled, randomized trial of individuals with alcohol use disorder (AUD) to receive weekly injections of either tirzepatide (n=10) or matching placebo (n=10). The primary aim is to determine the effects of tirzepatide on cue-reactivity among individuals with AUD. The secondary aim is to assess the safety and preliminary efficacy of tirzepatide for AUD.

Sponsor: Brigham and Women's Hospital

Who Can Participate

Inclusion Criteria

English speaking adults aged 18 and above
Diagnosed with current DSM-5 alcohol use disorder
Willing and able to physically travel to BWH CCI outpatient facilities for study visits

Exclusion Criteria

CIWA score at screening ≥ 8.
Psychotic disorder, active suicidality or homicidality or any psychiatric condition that impair ability to provide informed consent
Any lifetime diagnosis of eating disorders including anorexia, bulimia, binge eating, or avoidant/restrictive food intake disorder
BMI\<23 mg/kg2
Current or lifetime diagnosis of Type 1 or Type 2 diabetes
Current (or within 30 days of enrollment) use of any anti-obesity medications or medications with glucose lowering properties (including GLP-1 analogues, sulfonylurea, insulin, metformin, thiazolidinediones, dipeptidyl peptidase-4 (DPP-IV) inhibitors, or sodium-glucose cotransporter-2 (SGLT-2) inhibitors)
Use of any GLP-1 agonist medications in the prior 3 months
Anticipating receipt of any other GLP-1 agonist medications during the trial
Personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
Current hypoglycemia as indicated by a blood sugar level of ≤70 mg/dL measured at the baseline visit
Calcitonin ≥ 50 ng/L
Triglycerides ≥500 mg/dL
Untreated cholelithiasis or gallbladder disease
Acute myocardial infarction, cerebrovascular accident (stroke), unstable angina, or congestive heart failure in the last 90 days
Uncontrolled hypertension at baseline, as indicated by an average blood pressure reading of \>180/110 after three successive readings
History of inflammatory bowel disease, bariatric surgery, pancreatitis, diabetic gastroparesis, or non-arteritic anterior ischemic optic neuropathy
Liver function test greater than 5 times upper normal limit
Renal impairment as indicated by eGFR of \<30
History of hypersensitivity or allergy to tirzepatide
Pregnant or breastfeeding
Anticipated to be enrolled in another clinical drug trial during participation in this trial
Any other reason or clinical condition that the investigators judge may interfere with study participation and/or be unsafe for a participant

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Jamaica Plain?

Yes, this clinical trial (NCT06727331) has an active research site in Jamaica Plain, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Alcohol Use Disorder Treatment Options in Jamaica Plain, MA

If you're searching for alcohol use disorder treatment options in Jamaica Plain, MA, this clinical trial (NCT06727331) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Jamaica Plain research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced alcohol use disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all alcohol use disorder clinical trials near you to find additional studies recruiting in your area.

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